BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

272 related articles for article (PubMed ID: 32931865)

  • 1. Simultaneous Targeting of RSK and AKT Efficiently Inhibits YB-1-Mediated Repair of Ionizing Radiation-Induced DNA Double-Strand Breaks in Breast Cancer Cells.
    Lettau K; Zips D; Toulany M
    Int J Radiat Oncol Biol Phys; 2021 Feb; 109(2):567-580. PubMed ID: 32931865
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Impact of oncogenic K-RAS on YB-1 phosphorylation induced by ionizing radiation.
    Toulany M; Schickfluss TA; Eicheler W; Kehlbach R; Schittek B; Rodemann HP
    Breast Cancer Res; 2011 Mar; 13(2):R28. PubMed ID: 21392397
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fisetin induces DNA double-strand break and interferes with the repair of radiation-induced damage to radiosensitize triple negative breast cancer cells.
    Khozooei S; Lettau K; Barletta F; Jost T; Rebholz S; Veerappan S; Franz-Wachtel M; Macek B; Iliakis G; Distel LV; Zips D; Toulany M
    J Exp Clin Cancer Res; 2022 Aug; 41(1):256. PubMed ID: 35989353
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fisetin overcomes non-targetability of mutated KRAS induced YB-1 signaling in colorectal cancer cells and improves radiosensitivity by blocking repair of radiation-induced DNA double-strand breaks.
    Khozooei S; Veerappan S; Bonzheim I; Singer S; Gani C; Toulany M
    Radiother Oncol; 2023 Nov; 188():109867. PubMed ID: 37634766
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stress-Induced Phosphorylation of Nuclear YB-1 Depends on Nuclear Trafficking of p90 Ribosomal S6 Kinase.
    Tiwari A; Rebholz S; Maier E; Dehghan Harati M; Zips D; Sers C; Rodemann HP; Toulany M
    Int J Mol Sci; 2018 Aug; 19(8):. PubMed ID: 30126195
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dual Targeting of Akt and mTORC1 Impairs Repair of DNA Double-Strand Breaks and Increases Radiation Sensitivity of Human Tumor Cells.
    Holler M; Grottke A; Mueck K; Manes J; Jücker M; Rodemann HP; Toulany M
    PLoS One; 2016; 11(5):e0154745. PubMed ID: 27137757
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair.
    Toulany M; Kehlbach R; Florczak U; Sak A; Wang S; Chen J; Lobrich M; Rodemann HP
    Mol Cancer Ther; 2008 Jul; 7(7):1772-81. PubMed ID: 18644989
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1).
    Reipas KM; Law JH; Couto N; Islam S; Li Y; Li H; Cherkasov A; Jung K; Cheema AS; Jones SJ; Hassell JA; Dunn SE
    Oncotarget; 2013 Feb; 4(2):329-45. PubMed ID: 23593654
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Blockage of epidermal growth factor receptor-phosphatidylinositol 3-kinase-AKT signaling increases radiosensitivity of K-RAS mutated human tumor cells in vitro by affecting DNA repair.
    Toulany M; Kasten-Pisula U; Brammer I; Wang S; Chen J; Dittmann K; Baumann M; Dikomey E; Rodemann HP
    Clin Cancer Res; 2006 Jul; 12(13):4119-26. PubMed ID: 16818713
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells.
    Stratford AL; Fry CJ; Desilets C; Davies AH; Cho YY; Li Y; Dong Z; Berquin IM; Roux PP; Dunn SE
    Breast Cancer Res; 2008; 10(6):R99. PubMed ID: 19036157
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting p90 ribosomal S6 kinase eliminates tumor-initiating cells by inactivating Y-box binding protein-1 in triple-negative breast cancers.
    Stratford AL; Reipas K; Hu K; Fotovati A; Brough R; Frankum J; Takhar M; Watson P; Ashworth A; Lord CJ; Lasham A; Print CG; Dunn SE
    Stem Cells; 2012 Jul; 30(7):1338-48. PubMed ID: 22674792
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A common Chk1-dependent phenotype of DNA double-strand break suppression in two distinct radioresistant cancer types.
    Dinkelborg PH; Wang M; Gheorghiu L; Gurski JM; Hong TS; Benes CH; Juric D; Jimenez RB; Borgmann K; Willers H
    Breast Cancer Res Treat; 2019 Apr; 174(3):605-613. PubMed ID: 30607635
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PI3K-Akt signaling regulates basal, but MAP-kinase signaling regulates radiation-induced XRCC1 expression in human tumor cells in vitro.
    Toulany M; Dittmann K; Fehrenbacher B; Schaller M; Baumann M; Rodemann HP
    DNA Repair (Amst); 2008 Oct; 7(10):1746-56. PubMed ID: 18678286
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 2-Methoxyestradiol-induced radiosensitization is independent of SOD but depends on inhibition of Akt and DNA-PKcs activities.
    Florczak U; Toulany M; Kehlbach R; Peter Rodemann H
    Radiother Oncol; 2009 Sep; 92(3):334-8. PubMed ID: 19589609
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting ribosomal S6 kinases/Y-box binding protein-1 signaling improves cellular sensitivity to taxane in prostate cancer.
    Shiota M; Itsumi M; Yokomizo A; Takeuchi A; Imada K; Kashiwagi E; Inokuchi J; Tatsugami K; Uchiumi T; Naito S
    Prostate; 2014 Jun; 74(8):829-38. PubMed ID: 24729449
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dual Targeting of Y-Box Binding Protein-1 and Akt Inhibits Proliferation and Enhances the Chemosensitivity of Colorectal Cancer Cells.
    Maier E; Attenberger F; Tiwari A; Lettau K; Rebholz S; Fehrenbacher B; Schaller M; Gani C; Toulany M
    Cancers (Basel); 2019 Apr; 11(4):. PubMed ID: 31010234
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA-PK inhibition by NU7441 sensitizes breast cancer cells to ionizing radiation and doxorubicin.
    Ciszewski WM; Tavecchio M; Dastych J; Curtin NJ
    Breast Cancer Res Treat; 2014 Jan; 143(1):47-55. PubMed ID: 24292814
    [TBL] [Abstract][Full Text] [Related]  

  • 18. BMS-345541 sensitizes MCF-7 breast cancer cells to ionizing radiation by selective inhibition of homologous recombinational repair of DNA double-strand breaks.
    Wu L; Shao L; Li M; Zheng J; Wang J; Feng W; Chang J; Wang Y; Hauer-Jensen M; Zhou D
    Radiat Res; 2013 Feb; 179(2):160-70. PubMed ID: 23259762
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Blocking Y-Box Binding Protein-1 through Simultaneous Targeting of PI3K and MAPK in Triple Negative Breast Cancers.
    Tiwari A; Iida M; Kosnopfel C; Abbariki M; Menegakis A; Fehrenbacher B; Maier J; Schaller M; Brucker SY; Wheeler DL; Harari PM; Rothbauer U; Schittek B; Zips D; Toulany M
    Cancers (Basel); 2020 Sep; 12(10):. PubMed ID: 33003386
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regorafenib sensitizes human breast cancer cells to radiation by inhibiting multiple kinases and inducing DNA damage.
    Mehta M; Griffith J; Panneerselvam J; Babu A; Mani J; Herman T; Ramesh R; Munshi A
    Int J Radiat Biol; 2021; 97(8):1109-1120. PubMed ID: 32052681
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.