BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 32946005)

  • 1. Solid state NMR assignments of a human λ-III immunoglobulin light chain amyloid fibril.
    Pradhan T; Annamalai K; Sarkar R; Hegenbart U; Schönland S; Fändrich M; Reif B
    Biomol NMR Assign; 2021 Apr; 15(1):9-16. PubMed ID: 32946005
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Seeded fibrils of the germline variant of human λ-III immunoglobulin light chain FOR005 have a similar core as patient fibrils with reduced stability.
    Pradhan T; Annamalai K; Sarkar R; Huhn S; Hegenbart U; Schönland S; Fändrich M; Reif B
    J Biol Chem; 2020 Dec; 295(52):18474-18484. PubMed ID: 33093170
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanistic insights into the aggregation pathway of the patient-derived immunoglobulin light chain variable domain protein FOR005.
    Pradhan T; Sarkar R; Meighen-Berger KM; Feige MJ; Zacharias M; Reif B
    Nat Commun; 2023 Jun; 14(1):3755. PubMed ID: 37353525
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Solid-state NMR chemical shift assignments for AL-09 V
    Piehl DW; Blancas-Mejía LM; Ramirez-Alvarado M; Rienstra CM
    Biomol NMR Assign; 2017 Apr; 11(1):45-50. PubMed ID: 27771830
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Fatal amyloid formation in a patient's antibody light chain is caused by a single point mutation.
    Kazman P; Vielberg MT; Pulido Cendales MD; Hunziger L; Weber B; Hegenbart U; Zacharias M; Köhler R; Schönland S; Groll M; Buchner J
    Elife; 2020 Mar; 9():. PubMed ID: 32151314
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light-chain amyloidosis.
    Brumshtein B; Esswein SR; Sawaya MR; Rosenberg G; Ly AT; Landau M; Eisenberg DS
    J Biol Chem; 2018 Dec; 293(51):19659-19671. PubMed ID: 30355736
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular mechanism of amyloidogenic mutations in hypervariable regions of antibody light chains.
    Rottenaicher GJ; Weber B; Rührnößl F; Kazman P; Absmeier RM; Hitzenberger M; Zacharias M; Buchner J
    J Biol Chem; 2021; 296():100334. PubMed ID: 33508322
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient.
    Swuec P; Lavatelli F; Tasaki M; Paissoni C; Rognoni P; Maritan M; Brambilla F; Milani P; Mauri P; Camilloni C; Palladini G; Merlini G; Ricagno S; Bolognesi M
    Nat Commun; 2019 Mar; 10(1):1269. PubMed ID: 30894521
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cryo-EM reveals structural breaks in a patient-derived amyloid fibril from systemic AL amyloidosis.
    Radamaker L; Baur J; Huhn S; Haupt C; Hegenbart U; Schönland S; Bansal A; Schmidt M; Fändrich M
    Nat Commun; 2021 Feb; 12(1):875. PubMed ID: 33558536
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A Substantial Structural Conversion of the Native Monomer Leads to in-Register Parallel Amyloid Fibril Formation in Light-Chain Amyloidosis.
    Lecoq L; Wiegand T; Rodriguez-Alvarez FJ; Cadalbert R; Herrera GA; Del Pozo-Yauner L; Meier BH; Böckmann A
    Chembiochem; 2019 Apr; 20(8):1027-1031. PubMed ID: 30565364
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cryo-EM structure of a light chain-derived amyloid fibril from a patient with systemic AL amyloidosis.
    Radamaker L; Lin YH; Annamalai K; Huhn S; Hegenbart U; Schönland SO; Fritz G; Schmidt M; Fändrich M
    Nat Commun; 2019 Mar; 10(1):1103. PubMed ID: 30894526
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Partially folded intermediates as critical precursors of light chain amyloid fibrils and amorphous aggregates.
    Khurana R; Gillespie JR; Talapatra A; Minert LJ; Ionescu-Zanetti C; Millett I; Fink AL
    Biochemistry; 2001 Mar; 40(12):3525-35. PubMed ID: 11297418
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Kinetic control in protein folding for light chain amyloidosis and the differential effects of somatic mutations.
    Blancas-Mejía LM; Tischer A; Thompson JR; Tai J; Wang L; Auton M; Ramirez-Alvarado M
    J Mol Biol; 2014 Jan; 426(2):347-61. PubMed ID: 24157440
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Coexistence of protein AA and immunoglobulin light-chain fragments in amyloid fibrils.
    Westermark P; Natvig JB; Anders RF; Sletten K; Husby G
    Scand J Immunol; 1976; 5(1-2):31-6. PubMed ID: 57640
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential effects on light chain amyloid formation depend on mutations and type of glycosaminoglycans.
    Blancas-Mejía LM; Hammernik J; Marin-Argany M; Ramirez-Alvarado M
    J Biol Chem; 2015 Feb; 290(8):4953-4965. PubMed ID: 25538238
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutations in specific structural regions of immunoglobulin light chains are associated with free light chain levels in patients with AL amyloidosis.
    Poshusta TL; Sikkink LA; Leung N; Clark RJ; Dispenzieri A; Ramirez-Alvarado M
    PLoS One; 2009; 4(4):e5169. PubMed ID: 19365555
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mass spectrometry characterization of light chain fragmentation sites in cardiac AL amyloidosis: insights into the timing of proteolysis.
    Lavatelli F; Mazzini G; Ricagno S; Iavarone F; Rognoni P; Milani P; Nuvolone M; Swuec P; Caminito S; Tasaki M; Chaves-Sanjuan A; Urbani A; Merlini G; Palladini G
    J Biol Chem; 2020 Dec; 295(49):16572-16584. PubMed ID: 32952127
    [TBL] [Abstract][Full Text] [Related]  

  • 18. (1)H, (15)N and (13)C resonance assignments for 3rC and 3rCWP: amyloidogenic variants of imunoglobulin λ 3 light-chain.
    Gil-Rodríguez P; Amero C
    Biomol NMR Assign; 2015 Apr; 9(1):139-42. PubMed ID: 24816896
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis.
    Karimi-Farsijani S; Pfeiffer PB; Banerjee S; Baur J; Kuhn L; Kupfer N; Hegenbart U; Schönland SO; Wiese S; Haupt C; Schmidt M; Fändrich M
    Nat Commun; 2024 Jun; 15(1):5121. PubMed ID: 38879609
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A constant domain mutation in a patient-derived antibody light chain reveals principles of AL amyloidosis.
    Rottenaicher GJ; Absmeier RM; Meier L; Zacharias M; Buchner J
    Commun Biol; 2023 Feb; 6(1):209. PubMed ID: 36823438
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.