BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 32947020)

  • 1. Perlecan, a modular instructive proteoglycan with diverse functional properties.
    Melrose J
    Int J Biochem Cell Biol; 2020 Nov; 128():105849. PubMed ID: 32947020
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Perlecan, A Multi-Functional, Cell-Instructive, Matrix-Stabilizing Proteoglycan With Roles in Tissue Development Has Relevance to Connective Tissue Repair and Regeneration.
    Hayes AJ; Farrugia BL; Biose IJ; Bix GJ; Melrose J
    Front Cell Dev Biol; 2022; 10():856261. PubMed ID: 35433700
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Endorepellin, the angiostatic module of perlecan, interacts with both the α2β1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism.
    Goyal A; Pal N; Concannon M; Paul M; Doran M; Poluzzi C; Sekiguchi K; Whitelock JM; Neill T; Iozzo RV
    J Biol Chem; 2011 Jul; 286(29):25947-62. PubMed ID: 21596751
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Endorepellin laminin-like globular 1/2 domains bind Ig3-5 of vascular endothelial growth factor (VEGF) receptor 2 and block pro-angiogenic signaling by VEGFA in endothelial cells.
    Willis CD; Poluzzi C; Mongiat M; Iozzo RV
    FEBS J; 2013 May; 280(10):2271-84. PubMed ID: 23374253
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Endorepellin evokes autophagy in endothelial cells.
    Poluzzi C; Casulli J; Goyal A; Mercer TJ; Neill T; Iozzo RV
    J Biol Chem; 2014 Jun; 289(23):16114-28. PubMed ID: 24737315
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Border patrol: insights into the unique role of perlecan/heparan sulfate proteoglycan 2 at cell and tissue borders.
    Farach-Carson MC; Warren CR; Harrington DA; Carson DD
    Matrix Biol; 2014 Feb; 34():64-79. PubMed ID: 24001398
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mast cells produce novel shorter forms of perlecan that contain functional endorepellin: a role in angiogenesis and wound healing.
    Jung M; Lord MS; Cheng B; Lyons JG; Alkhouri H; Hughes JM; McCarthy SJ; Iozzo RV; Whitelock JM
    J Biol Chem; 2013 Feb; 288(5):3289-304. PubMed ID: 23235151
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin.
    Bix G; Fu J; Gonzalez EM; Macro L; Barker A; Campbell S; Zutter MM; Santoro SA; Kim JK; Höök M; Reed CC; Iozzo RV
    J Cell Biol; 2004 Jul; 166(1):97-109. PubMed ID: 15240572
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.
    Nakamura K; Ikeuchi T; Nara K; Rhodes CS; Zhang P; Chiba Y; Kazuno S; Miura Y; Ago T; Arikawa-Hirasawa E; Mukouyama YS; Yamada Y
    J Cell Biol; 2019 Oct; 218(10):3506-3525. PubMed ID: 31541017
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A current view of perlecan in physiology and pathology: A mosaic of functions.
    Gubbiotti MA; Neill T; Iozzo RV
    Matrix Biol; 2017 Jan; 57-58():285-298. PubMed ID: 27613501
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Recombinant Domain V of Human Perlecan Is a Bioactive Vascular Proteoglycan.
    Rnjak-Kovacina J; Tang F; Lin X; Whitelock JM; Lord MS
    Biotechnol J; 2017 Dec; 12(12):. PubMed ID: 28846206
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling.
    Lord MS; Chuang CY; Melrose J; Davies MJ; Iozzo RV; Whitelock JM
    Matrix Biol; 2014 Apr; 35():112-22. PubMed ID: 24509440
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Perlecan/Hspg2 deficiency alters the pericellular space of the lacunocanalicular system surrounding osteocytic processes in cortical bone.
    Thompson WR; Modla S; Grindel BJ; Czymmek KJ; Kirn-Safran CB; Wang L; Duncan RL; Farach-Carson MC
    J Bone Miner Res; 2011 Mar; 26(3):618-29. PubMed ID: 20814969
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Perlecan in Pericellular Mechanosensory Cell-Matrix Communication, Extracellular Matrix Stabilisation and Mechanoregulation of Load-Bearing Connective Tissues.
    Guilak F; Hayes AJ; Melrose J
    Int J Mol Sci; 2021 Mar; 22(5):. PubMed ID: 33800241
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The ovine newborn and human foetal intervertebral disc contain perlecan and aggrecan variably substituted with native 7D4 CS sulphation motif: spatiotemporal immunolocalisation and co-distribution with Notch-1 in the human foetal disc.
    Shu C; Hughes C; Smith SM; Smith MM; Hayes A; Caterson B; Little CB; Melrose J
    Glycoconj J; 2013 Oct; 30(7):717-25. PubMed ID: 23756834
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Perlecan Domain V Inhibits Amyloid-β Induced Activation of the α2β1 Integrin-Mediated Neurotoxic Signaling Cascade.
    Parham CL; Shaw C; Auckland LD; Dickeson SK; Griswold-Prenner I; Bix G
    J Alzheimers Dis; 2016 Oct; 54(4):1629-1647. PubMed ID: 27636841
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pentosan Polysulfate, a Semisynthetic Heparinoid Disease-Modifying Osteoarthritic Drug with Roles in Intervertebral Disc Repair Biology Emulating the Stem Cell Instructive and Tissue Reparative Properties of Heparan Sulfate.
    Smith MM; Hayes AJ; Melrose J
    Stem Cells Dev; 2022 Aug; 31(15-16):406-430. PubMed ID: 35102748
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Matrilysin/MMP-7 Cleavage of Perlecan/HSPG2 Complexed with Semaphorin 3A Supports FAK-Mediated Stromal Invasion by Prostate Cancer Cells.
    Grindel BJ; Martinez JR; Tellman TV; Harrington DA; Zafar H; Nakhleh L; Chung LW; Farach-Carson MC
    Sci Rep; 2018 May; 8(1):7262. PubMed ID: 29740048
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The role of perlecan and endorepellin in the control of tumor angiogenesis and endothelial cell autophagy.
    Douglass S; Goyal A; Iozzo RV
    Connect Tissue Res; 2015; 56(5):381-91. PubMed ID: 26181327
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Matrilysin/matrix metalloproteinase-7(MMP7) cleavage of perlecan/HSPG2 creates a molecular switch to alter prostate cancer cell behavior.
    Grindel BJ; Martinez JR; Pennington CL; Muldoon M; Stave J; Chung LW; Farach-Carson MC
    Matrix Biol; 2014 Jun; 36():64-76. PubMed ID: 24833109
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.