These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 32956454)

  • 1. HRI depletion cooperates with pharmacologic inducers to elevate fetal hemoglobin and reduce sickle cell formation.
    Peslak SA; Khandros E; Huang P; Lan X; Geronimo CL; Grevet JD; Abdulmalik O; Zhang Z; Giardine BM; Keller CA; Shi J; Hardison RC; Blobel GA
    Blood Adv; 2020 Sep; 4(18):4560-4572. PubMed ID: 32956454
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells.
    Grevet JD; Lan X; Hamagami N; Edwards CR; Sankaranarayanan L; Ji X; Bhardwaj SK; Face CJ; Posocco DF; Abdulmalik O; Keller CA; Giardine B; Sidoli S; Garcia BA; Chou ST; Liebhaber SA; Hardison RC; Shi J; Blobel GA
    Science; 2018 Jul; 361(6399):285-290. PubMed ID: 30026227
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Understanding heterogeneity of fetal hemoglobin induction through comparative analysis of F and A erythroblasts.
    Khandros E; Huang P; Peslak SA; Sharma M; Abdulmalik O; Giardine BM; Zhang Z; Keller CA; Hardison RC; Blobel GA
    Blood; 2020 May; 135(22):1957-1968. PubMed ID: 32268371
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cells.
    Moutouh-de Parseval LA; Verhelle D; Glezer E; Jensen-Pergakes K; Ferguson GD; Corral LG; Morris CL; Muller G; Brady H; Chan K
    J Clin Invest; 2008 Jan; 118(1):248-58. PubMed ID: 18064299
    [TBL] [Abstract][Full Text] [Related]  

  • 5. EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.
    Renneville A; Van Galen P; Canver MC; McConkey M; Krill-Burger JM; Dorfman DM; Holson EB; Bernstein BE; Orkin SH; Bauer DE; Ebert BL
    Blood; 2015 Oct; 126(16):1930-9. PubMed ID: 26320100
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metformin induces FOXO3-dependent fetal hemoglobin production in human primary erythroid cells.
    Zhang Y; Paikari A; Sumazin P; Ginter Summarell CC; Crosby JR; Boerwinkle E; Weiss MJ; Sheehan VA
    Blood; 2018 Jul; 132(3):321-333. PubMed ID: 29884740
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells.
    Lan X; Khandros E; Huang P; Peslak SA; Bhardwaj SK; Grevet JD; Abdulmalik O; Wang H; Keller CA; Giardine B; Baeza J; Duffner ER; El Demerdash O; Wu XS; Vakoc CR; Garcia BA; Hardison RC; Shi J; Blobel GA
    Blood Adv; 2019 May; 3(10):1586-1597. PubMed ID: 31126914
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The proinflammatory cytokine GM-CSF downregulates fetal hemoglobin expression by attenuating the cAMP-dependent pathway in sickle cell disease.
    Ikuta T; Adekile AD; Gutsaeva DR; Parkerson JB; Yerigenahally SD; Clair B; Kutlar A; Odo N; Head CA
    Blood Cells Mol Dis; 2011 Dec; 47(4):235-42. PubMed ID: 21945571
    [TBL] [Abstract][Full Text] [Related]  

  • 9. UNC0638 induces high levels of fetal hemoglobin expression in β-thalassemia/HbE erythroid progenitor cells.
    Nualkaew T; Khamphikham P; Pongpaksupasin P; Kaewsakulthong W; Songdej D; Paiboonsukwong K; Sripichai O; Engel JD; Hongeng S; Fucharoen S; Jearawiriyapaisarn N
    Ann Hematol; 2020 Sep; 99(9):2027-2036. PubMed ID: 32567028
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Conjugate prodrug AN-233 induces fetal hemoglobin expression in sickle erythroid progenitors and β-YAC transgenic mice.
    Oseghale AR; Zhu X; Li B; Peterson KR; Nudelman A; Rephaeli A; Xu H; Pace BS
    Blood Cells Mol Dis; 2019 Nov; 79():102345. PubMed ID: 31351219
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Forced chromatin looping raises fetal hemoglobin in adult sickle cells to higher levels than pharmacologic inducers.
    Breda L; Motta I; Lourenco S; Gemmo C; Deng W; Rupon JW; Abdulmalik OY; Manwani D; Blobel GA; Rivella S
    Blood; 2016 Aug; 128(8):1139-43. PubMed ID: 27405777
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Induction of fetal hemoglobin in the treatment of sickle cell disease.
    Fathallah H; Atweh GF
    Hematology Am Soc Hematol Educ Program; 2006; ():58-62. PubMed ID: 17124041
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Spectrum of fetal hemoglobin responses in sickle cell patients treated with hydroxyurea: the National Institutes of Health experience.
    Rodgers GP
    Semin Oncol; 1992 Jun; 19(3 Suppl 9):67-73. PubMed ID: 1379375
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Computational identification of potential modulators of heme-regulated inhibitor (HRI) for pharmacological intervention against sickle cell disease.
    Owoloye AJ; Olubode SO; Ogunleye A; Idowu ET; Oyebola KM
    Res Sq; 2023 Dec; ():. PubMed ID: 38168168
    [TBL] [Abstract][Full Text] [Related]  

  • 15. New Synthetic Isoxazole Derivatives Acting as Potent Inducers of Fetal Hemoglobin in Erythroid Precursor Cells Isolated from β-Thalassemic Patients.
    Zuccato C; Cosenza LC; Tupini C; Finotti A; Sacchetti G; Simoni D; Gambari R; Lampronti I
    Molecules; 2023 Dec; 29(1):. PubMed ID: 38202591
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enhanced fetal hemoglobin production by phenylacetate and 4-phenylbutyrate in erythroid precursors derived from normal donors and patients with sickle cell anemia and beta-thalassemia.
    Fibach E; Prasanna P; Rodgers GP; Samid D
    Blood; 1993 Oct; 82(7):2203-9. PubMed ID: 7691251
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Potent and orally active purine-based fetal hemoglobin inducers for treating β-thalassemia and sickle cell disease.
    Lai ZS; Yeh TK; Chou YC; Hsu T; Lu CT; Kung FC; Hsieh MY; Lin CH; Chen CT; James Shen CK; Jiaang WT
    Eur J Med Chem; 2021 Jan; 209():112938. PubMed ID: 33109398
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genetic modifiers of HbF and response to hydroxyurea in sickle cell disease.
    Green NS; Barral S
    Pediatr Blood Cancer; 2011 Feb; 56(2):177-81. PubMed ID: 20830771
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro induction of fetal hemoglobin in human erythroid progenitor cells.
    Ho JA; Pickens CV; Gamcsik MP; Colvin OM; Ware RE
    Exp Hematol; 2003 Jul; 31(7):586-91. PubMed ID: 12842703
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification and characterization of RBM12 as a novel regulator of fetal hemoglobin expression.
    Wakabayashi A; Kihiu M; Sharma M; Thrasher AJ; Saari MS; Quesnel-Vallières M; Abdulmalik O; Peslak SA; Khandros E; Keller CA; Giardine BM; Barash Y; Hardison RC; Shi J; Blobel GA
    Blood Adv; 2022 Dec; 6(23):5956-5968. PubMed ID: 35622975
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.