BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

308 related articles for article (PubMed ID: 32958755)

  • 1. The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution.
    Ballhausen A; Przybilla MJ; Jendrusch M; Haupt S; Pfaffendorf E; Seidler F; Witt J; Hernandez Sanchez A; Urban K; Draxlbauer M; Krausert S; Ahadova A; Kalteis MS; Pfuderer PL; Heid D; Stichel D; Gebert J; Bonsack M; Schott S; Bläker H; Seppälä T; Mecklin JP; Ten Broeke S; Nielsen M; Heuveline V; Krzykalla J; Benner A; Riemer AB; von Knebel Doeberitz M; Kloor M
    Nat Commun; 2020 Sep; 11(1):4740. PubMed ID: 32958755
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Immune Biology of Microsatellite-Unstable Cancer.
    Kloor M; von Knebel Doeberitz M
    Trends Cancer; 2016 Mar; 2(3):121-133. PubMed ID: 28741532
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Immunogenic peptides generated by frameshift mutations in DNA mismatch repair-deficient cancer cells.
    Schwitalle Y; Linnebacher M; Ripberger E; Gebert J; von Knebel Doeberitz M
    Cancer Immun; 2004 Nov; 4():14. PubMed ID: 15563124
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Shared Immunogenic Poly-Epitope Frameshift Mutations in Microsatellite Unstable Tumors.
    Roudko V; Bozkus CC; Orfanelli T; McClain CB; Carr C; O'Donnell T; Chakraborty L; Samstein R; Huang KL; Blank SV; Greenbaum B; Bhardwaj N
    Cell; 2020 Dec; 183(6):1634-1649.e17. PubMed ID: 33259803
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Opportunities for immunotherapy in microsatellite instable colorectal cancer.
    Westdorp H; Fennemann FL; Weren RD; Bisseling TM; Ligtenberg MJ; Figdor CG; Schreibelt G; Hoogerbrugge N; Wimmers F; de Vries IJ
    Cancer Immunol Immunother; 2016 Oct; 65(10):1249-59. PubMed ID: 27060000
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Genetic Vaccine Encoding Shared Cancer Neoantigens to Treat Tumors with Microsatellite Instability.
    Leoni G; D'Alise AM; Cotugno G; Langone F; Garzia I; De Lucia M; Fichera I; Vitale R; Bignone V; Tucci FG; Mori F; Leuzzi A; Di Matteo E; Troise F; Abbate A; Merone R; Ruzza V; Diodoro MG; Yadav M; Gordon-Alonso M; Vanhaver C; Panigada M; Soprana E; Siccardi A; Folgori A; Colloca S; van der Bruggen P; Nicosia A; Lahm A; Catanese MT; Scarselli E
    Cancer Res; 2020 Sep; 80(18):3972-3982. PubMed ID: 32690723
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Recurrent Frameshift Neoantigen Vaccine Elicits Protective Immunity With Reduced Tumor Burden and Improved Overall Survival in a Lynch Syndrome Mouse Model.
    Gebert J; Gelincik O; Oezcan-Wahlbrink M; Marshall JD; Hernandez-Sanchez A; Urban K; Long M; Cortes E; Tosti E; Katzenmaier EM; Song Y; Elsaadi A; Deng N; Vilar E; Fuchs V; Nelius N; Yuan YP; Ahadova A; Sei S; Shoemaker RH; Umar A; Wei L; Liu S; Bork P; Edelmann W; von Knebel Doeberitz M; Lipkin SM; Kloor M
    Gastroenterology; 2021 Oct; 161(4):1288-1302.e13. PubMed ID: 34224739
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A Frameshift Peptide Neoantigen-Based Vaccine for Mismatch Repair-Deficient Cancers: A Phase I/IIa Clinical Trial.
    Kloor M; Reuschenbach M; Pauligk C; Karbach J; Rafiyan MR; Al-Batran SE; Tariverdian M; Jäger E; von Knebel Doeberitz M
    Clin Cancer Res; 2020 Sep; 26(17):4503-4510. PubMed ID: 32540851
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Frameshift mutations of human gastrin receptor gene (hGARE) in gastrointestinal cancers with microsatellite instability.
    Laghi L; Ranzani GN; Bianchi P; Mori A; Heinimann K; Orbetegli O; Spaudo MR; Luinetti O; Francisconi S; Roncalli M; Solcia E; Malesci A
    Lab Invest; 2002 Mar; 82(3):265-71. PubMed ID: 11896205
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Frameshift-derived neoantigens constitute immunotherapeutic targets for patients with microsatellite-instable haematological malignancies: frameshift peptides for treating MSI+ blood cancers.
    Maletzki C; Schmidt F; Dirks WG; Schmitt M; Linnebacher M
    Eur J Cancer; 2013 Jul; 49(11):2587-95. PubMed ID: 23561850
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Detection of coding microsatellite frameshift mutations in DNA mismatch repair-deficient mouse intestinal tumors.
    Woerner SM; Tosti E; Yuan YP; Kloor M; Bork P; Edelmann W; Gebert J
    Mol Carcinog; 2015 Nov; 54(11):1376-86. PubMed ID: 25213383
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The putative tumor suppressor AIM2 is frequently affected by different genetic alterations in microsatellite unstable colon cancers.
    Woerner SM; Kloor M; Schwitalle Y; Youmans H; Doeberitz Mv; Gebert J; Dihlmann S
    Genes Chromosomes Cancer; 2007 Dec; 46(12):1080-9. PubMed ID: 17726700
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Frameshift peptide-derived T-cell epitopes: a source of novel tumor-specific antigens.
    Linnebacher M; Gebert J; Rudy W; Woerner S; Yuan YP; Bork P; von Knebel Doeberitz M
    Int J Cancer; 2001 Jul; 93(1):6-11. PubMed ID: 11391614
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Lack of HLA class II antigen expression in microsatellite unstable colorectal carcinomas is caused by mutations in HLA class II regulatory genes.
    Michel S; Linnebacher M; Alcaniz J; Voss M; Wagner R; Dippold W; Becker C; von Knebel Doeberitz M; Ferrone S; Kloor M
    Int J Cancer; 2010 Aug; 127(4):889-98. PubMed ID: 20013806
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genomic Landscape of Lynch Syndrome Colorectal Neoplasia Identifies Shared Mutated Neoantigens for Immunoprevention.
    Bolivar AM; Duzagac F; Deng N; Reyes-Uribe L; Chang K; Wu W; Bowen CM; Taggart MW; Thirumurthi S; Lynch PM; You YN; Rodriguez-Pascual J; Lipkin SM; Kopetz S; Scheet P; Lizee GA; Reuben A; Sinha KM; Vilar E
    Gastroenterology; 2024 May; 166(5):787-801.e11. PubMed ID: 38244726
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tumor-specific immunological recognition of frameshift-mutated peptides in colon cancer with microsatellite instability.
    Ishikawa T; Fujita T; Suzuki Y; Okabe S; Yuasa Y; Iwai T; Kawakami Y
    Cancer Res; 2003 Sep; 63(17):5564-72. PubMed ID: 14500396
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Beta2-microglobulin mutations in microsatellite unstable colorectal tumors.
    Kloor M; Michel S; Buckowitz B; Rüschoff J; Büttner R; Holinski-Feder E; Dippold W; Wagner R; Tariverdian M; Benner A; Schwitalle Y; Kuchenbuch B; von Knebel Doeberitz M
    Int J Cancer; 2007 Jul; 121(2):454-8. PubMed ID: 17373663
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An MSI tumor specific frameshift mutation in a coding microsatellite of MSH3 encodes for HLA-A0201-restricted CD8+ cytotoxic T cell epitopes.
    Garbe Y; Maletzki C; Linnebacher M
    PLoS One; 2011; 6(11):e26517. PubMed ID: 22110587
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of the immune escape phenotype of human gastric cancers with and without high-frequency microsatellite instability.
    Hirata T; Yamamoto H; Taniguchi H; Horiuchi S; Oki M; Adachi Y; Imai K; Shinomura Y
    J Pathol; 2007 Apr; 211(5):516-523. PubMed ID: 17318812
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TGFBR2-dependent alterations of exosomal cargo and functions in DNA mismatch repair-deficient HCT116 colorectal cancer cells.
    Fricke F; Lee J; Michalak M; Warnken U; Hausser I; Suarez-Carmona M; Halama N; Schnölzer M; Kopitz J; Gebert J
    Cell Commun Signal; 2017 Apr; 15(1):14. PubMed ID: 28376875
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.