BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 32961238)

  • 1. Resolving Liquid-Liquid Phase Separation for a Peptide Fused Monoclonal Antibody by Formulation Optimization.
    Qi W; Alekseychyk L; Nuanmanee N; Temel DB; Jann V; Treuheit M; Razinkov V
    J Pharm Sci; 2021 Feb; 110(2):738-745. PubMed ID: 32961238
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Process optimization and protein engineering mitigated manufacturing challenges of a monoclonal antibody with liquid-liquid phase separation issue by disrupting inter-molecule electrostatic interactions.
    Du Q; Damschroder M; Pabst TM; Hunter AK; Wang WK; Luo H
    MAbs; 2019; 11(4):789-802. PubMed ID: 30913985
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Elucidating the weak protein-protein interaction mechanisms behind the liquid-liquid phase separation of a mAb solution by different types of additives.
    Wu G; Wang S; Tian Z; Zhang N; Sheng H; Dai W; Qian F
    Eur J Pharm Biopharm; 2017 Nov; 120():1-8. PubMed ID: 28754261
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effect of Excipients on Liquid-Liquid Phase Separation and Aggregation in Dual Variable Domain Immunoglobulin Protein Solutions.
    Raut AS; Kalonia DS
    Mol Pharm; 2016 Mar; 13(3):774-83. PubMed ID: 26756795
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Therapeutic Antibody Engineering To Improve Viscosity and Phase Separation Guided by Crystal Structure.
    Chow CK; Allan BW; Chai Q; Atwell S; Lu J
    Mol Pharm; 2016 Mar; 13(3):915-23. PubMed ID: 26849155
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Adenosine Triphosphate-Induced Rapid Liquid-Liquid Phase Separation of a Model IgG1 mAb.
    Tian Z; Qian F
    Mol Pharm; 2021 Jan; 18(1):267-274. PubMed ID: 33307701
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Suppression of Electrostatic Mediated Antibody Liquid-Liquid Phase Separation by Charged and Noncharged Preferentially Excluded Excipients.
    Banks DD; Cordia JF
    Mol Pharm; 2021 Mar; 18(3):1285-1292. PubMed ID: 33555888
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmaceutical Perspective on Opalescence and Liquid-Liquid Phase Separation in Protein Solutions.
    Raut AS; Kalonia DS
    Mol Pharm; 2016 May; 13(5):1431-44. PubMed ID: 27017836
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quantitative evaluation of colloidal stability of antibody solutions using PEG-induced liquid-liquid phase separation.
    Wang Y; Latypov RF; Lomakin A; Meyer JA; Kerwin BA; Vunnum S; Benedek GB
    Mol Pharm; 2014 May; 11(5):1391-402. PubMed ID: 24679215
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Investigating Liquid-Liquid Phase Separation of a Monoclonal Antibody Using Solution-State NMR Spectroscopy: Effect of Arg·Glu and Arg·HCl.
    Kheddo P; Bramham JE; Dearman RJ; Uddin S; van der Walle CF; Golovanov AP
    Mol Pharm; 2017 Aug; 14(8):2852-2860. PubMed ID: 28614662
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stability of a high-concentration monoclonal antibody solution produced by liquid-liquid phase separation.
    Bramham JE; Davies SA; Podmore A; Golovanov AP
    MAbs; 2021; 13(1):1940666. PubMed ID: 34225583
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Liquid-liquid phase separation causes high turbidity and pressure during low pH elution process in Protein A chromatography.
    Luo H; Lee N; Wang X; Li Y; Schmelzer A; Hunter AK; Pabst T; Wang WK
    J Chromatogr A; 2017 Mar; 1488():57-67. PubMed ID: 28159365
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Studying Excipient Modulated Physical Stability and Viscosity of Monoclonal Antibody Formulations Using Small-Angle Scattering.
    Xu AY; Castellanos MM; Mattison K; Krueger S; Curtis JE
    Mol Pharm; 2019 Oct; 16(10):4319-4338. PubMed ID: 31487466
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Liquid-Liquid Phase Separation in a Dual Variable Domain Immunoglobulin Protein Solution: Effect of Formulation Factors and Protein-Protein Interactions.
    Raut AS; Kalonia DS
    Mol Pharm; 2015 Sep; 12(9):3261-71. PubMed ID: 26237070
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Liquid-liquid phase separation of a monoclonal antibody at low ionic strength: Influence of anion charge and concentration.
    Reiche K; Hartl J; Blume A; Garidel P
    Biophys Chem; 2017 Jan; 220():7-19. PubMed ID: 27838577
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Relationship between Protein-Protein Interactions and Liquid-Liquid Phase Separation for Monoclonal Antibodies.
    Sibanda N; Shanmugam RK; Curtis R
    Mol Pharm; 2023 May; 20(5):2662-2674. PubMed ID: 37039349
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prediction of Liquid-Liquid Phase Separation at the Dissolving Drug Salt Particle Surface.
    Uekusa T; Sugano K
    Mol Pharm; 2023 Jun; 20(6):3140-3149. PubMed ID: 37183369
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comprehensive Regulation of Liquid-Liquid Phase Separation of Polypeptides.
    Wang Y; Xiang D; Chen S; Yang G
    Molecules; 2023 Sep; 28(18):. PubMed ID: 37764485
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Liquid-liquid phase separation of tau protein: The crucial role of electrostatic interactions.
    Boyko S; Qi X; Chen TH; Surewicz K; Surewicz WK
    J Biol Chem; 2019 Jul; 294(29):11054-11059. PubMed ID: 31097543
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Liquid-liquid phase transition of protein aqueous solutions isothermally induced by protein cross-linking.
    Wang Y; Annunziata O
    Langmuir; 2008 Mar; 24(6):2799-807. PubMed ID: 18229962
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.