BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 32961751)

  • 1. FRET-Based Sorting of Live Cells Reveals Shifted Balance between PLK1 and CDK1 Activities During Checkpoint Recovery.
    Lafranchi L; Müllers E; Rutishauser D; Lindqvist A
    Cells; 2020 Sep; 9(9):. PubMed ID: 32961751
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage.
    Tsvetkov L; Stern DF
    Cell Cycle; 2005 Jan; 4(1):166-71. PubMed ID: 15611664
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A predictive mathematical model of the DNA damage G2 checkpoint.
    Kesseler KJ; Blinov ML; Elston TC; Kaufmann WK; Simpson DA
    J Theor Biol; 2013 Mar; 320():159-69. PubMed ID: 23266715
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PLK1 Activation in Late G2 Sets Up Commitment to Mitosis.
    Gheghiani L; Loew D; Lombard B; Mansfeld J; Gavet O
    Cell Rep; 2017 Jun; 19(10):2060-2073. PubMed ID: 28591578
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ATR enforces the topoisomerase II-dependent G2 checkpoint through inhibition of Plk1 kinase.
    Deming PB; Flores KG; Downes CS; Paules RS; Kaufmann WK
    J Biol Chem; 2002 Sep; 277(39):36832-8. PubMed ID: 12147700
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sequential Cdk1 and Plk1 phosphorylation of protein tyrosine phosphatase 1B promotes mitotic cell death.
    O'Donovan DS; MacFhearraigh S; Whitfield J; Swigart LB; Evan GI; Mc Gee MM
    Cell Death Dis; 2013 Jan; 4(1):e468. PubMed ID: 23348582
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The auto-ubiquitylation of E3 ubiquitin-protein ligase Chfr at G2 phase is required for accumulation of polo-like kinase 1 and mitotic entry in mammalian cells.
    Kim JS; Park YY; Park SY; Cho H; Kang D; Cho H
    J Biol Chem; 2011 Sep; 286(35):30615-30623. PubMed ID: 21768102
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint.
    van Vugt MA; Gardino AK; Linding R; Ostheimer GJ; Reinhardt HC; Ong SE; Tan CS; Miao H; Keezer SM; Li J; Pawson T; Lewis TA; Carr SA; Smerdon SJ; Brummelkamp TR; Yaffe MB
    PLoS Biol; 2010 Jan; 8(1):e1000287. PubMed ID: 20126263
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitotic DNA damage response: Polo-like kinase-1 is dephosphorylated through ATM-Chk1 pathway.
    Lee HJ; Hwang HI; Jang YJ
    Cell Cycle; 2010 Jun; 9(12):2389-98. PubMed ID: 20581453
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tubulin-binding agents down-regulate matrix metalloproteinase-2 and -9 in human hormone-refractory prostate cancer cells – a critical role of Cdk1 in mitotic entry.
    Chang WL; Yu CC; Chen CS; Guh JH
    Biochem Pharmacol; 2015 Mar; 94(1):12-21. PubMed ID: 25615907
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mitotic entry: The interplay between Cdk1, Plk1 and Bora.
    Parrilla A; Cirillo L; Thomas Y; Gotta M; Pintard L; Santamaria A
    Cell Cycle; 2016 Dec; 15(23):3177-3182. PubMed ID: 27831827
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA Replication Determines Timing of Mitosis by Restricting CDK1 and PLK1 Activation.
    Lemmens B; Hegarat N; Akopyan K; Sala-Gaston J; Bartek J; Hochegger H; Lindqvist A
    Mol Cell; 2018 Jul; 71(1):117-128.e3. PubMed ID: 30008317
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Polo-like kinase 1 inhibits DNA damage response during mitosis.
    Benada J; Burdová K; Lidak T; von Morgen P; Macurek L
    Cell Cycle; 2015; 14(2):219-31. PubMed ID: 25607646
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.
    Lossaint G; Besnard E; Fisher D; Piette J; Dulić V
    Oncogene; 2011 Oct; 30(41):4261-74. PubMed ID: 21532626
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of Polo-like kinase 1 during the DNA damage response is mediated through loss of Aurora A recruitment by Bora.
    Bruinsma W; Aprelia M; García-Santisteban I; Kool J; Xu YJ; Medema RH
    Oncogene; 2017 Mar; 36(13):1840-1848. PubMed ID: 27721411
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PLK1 targets CtIP to promote microhomology-mediated end joining.
    Wang H; Qiu Z; Liu B; Wu Y; Ren J; Liu Y; Zhao Y; Wang Y; Hao S; Li Z; Peng B; Xu X
    Nucleic Acids Res; 2018 Nov; 46(20):10724-10739. PubMed ID: 30202980
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cdk1 activity is required for mitotic activation of aurora A during G2/M transition of human cells.
    Van Horn RD; Chu S; Fan L; Yin T; Du J; Beckmann R; Mader M; Zhu G; Toth J; Blanchard K; Ye XS
    J Biol Chem; 2010 Jul; 285(28):21849-57. PubMed ID: 20444701
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chk1 instability is coupled to mitotic cell death of p53-deficient cells in response to virus-induced DNA damage signaling.
    Jurvansuu J; Fragkos M; Ingemarsdotter C; Beard P
    J Mol Biol; 2007 Sep; 372(2):397-406. PubMed ID: 17663993
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase.
    Yim H; Erikson RL
    Proc Natl Acad Sci U S A; 2010 Nov; 107(46):19742-7. PubMed ID: 21041660
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Integrated computational model of cell cycle and checkpoint reveals different essential roles of Aurora-A and Plk1 in mitotic entry.
    Zou J; Luo SD; Wei YQ; Yang SY
    Mol Biosyst; 2011 Jan; 7(1):169-79. PubMed ID: 20978655
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.