These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 32966073)

  • 1. Radical SAM Enzyme Spore Photoproduct Lyase: Properties of the Ω Organometallic Intermediate and Identification of Stable Protein Radicals Formed during Substrate-Free Turnover.
    Pagnier A; Yang H; Jodts RJ; James CD; Shepard EM; Impano S; Broderick WE; Hoffman BM; Broderick JB
    J Am Chem Soc; 2020 Oct; 142(43):18652-18660. PubMed ID: 32966073
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ENDOR Spectroscopy Reveals the "Free" 5'-Deoxyadenosyl Radical in a Radical SAM Enzyme Active Site Actually is Chaperoned by Close Interaction with the Methionine-Bound [4Fe-4S]
    Yang H; Ho MB; Lundahl MN; Mosquera MA; Broderick WE; Broderick JB; Hoffman BM
    J Am Chem Soc; 2024 Feb; 146(6):3710-3720. PubMed ID: 38308759
    [No Abstract]   [Full Text] [Related]  

  • 3. Paradigm Shift for Radical S-Adenosyl-l-methionine Reactions: The Organometallic Intermediate Ω Is Central to Catalysis.
    Byer AS; Yang H; McDaniel EC; Kathiresan V; Impano S; Pagnier A; Watts H; Denler C; Vagstad AL; Piel J; Duschene KS; Shepard EM; Shields TP; Scott LG; Lilla EA; Yokoyama K; Broderick WE; Hoffman BM; Broderick JB
    J Am Chem Soc; 2018 Jul; 140(28):8634-8638. PubMed ID: 29954180
    [TBL] [Abstract][Full Text] [Related]  

  • 4.
    Lundahl MN; Sarksian R; Yang H; Jodts RJ; Pagnier A; Smith DF; Mosquera MA; van der Donk WA; Hoffman BM; Broderick WE; Broderick JB
    J Am Chem Soc; 2022 Mar; 144(11):5087-5098. PubMed ID: 35258967
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanism of Radical Initiation in the Radical S-Adenosyl-l-methionine Superfamily.
    Broderick WE; Hoffman BM; Broderick JB
    Acc Chem Res; 2018 Nov; 51(11):2611-2619. PubMed ID: 30346729
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanism of Radical Initiation in the Radical SAM Enzyme Superfamily.
    Hoffman BM; Broderick WE; Broderick JB
    Annu Rev Biochem; 2023 Jun; 92():333-349. PubMed ID: 37018846
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Radical SAM enzymes: Nature's choice for radical reactions.
    Broderick JB; Broderick WE; Hoffman BM
    FEBS Lett; 2023 Jan; 597(1):92-101. PubMed ID: 36251330
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Active-Site Controlled, Jahn-Teller Enabled Regioselectivity in Reductive S-C Bond Cleavage of
    Impano S; Yang H; Jodts RJ; Pagnier A; Swimley R; McDaniel EC; Shepard EM; Broderick WE; Broderick JB; Hoffman BM
    J Am Chem Soc; 2021 Jan; 143(1):335-348. PubMed ID: 33372786
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pyruvate formate-lyase activating enzyme: The catalytically active 5'-deoxyadenosyl radical caught in the act of H-atom abstraction.
    Lundahl MN; Yang H; Broderick WE; Hoffman BM; Broderick JB
    Proc Natl Acad Sci U S A; 2023 Nov; 120(47):e2314696120. PubMed ID: 37956301
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Photoinduced Electron Transfer in a Radical SAM Enzyme Generates an
    Yang H; Impano S; Shepard EM; James CD; Broderick WE; Broderick JB; Hoffman BM
    J Am Chem Soc; 2019 Oct; 141(40):16117-16124. PubMed ID: 31509404
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanistic studies of the radical SAM enzyme spore photoproduct lyase (SPL).
    Li L
    Biochim Biophys Acta; 2012 Nov; 1824(11):1264-77. PubMed ID: 22197590
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Substrate-Dependent Cleavage Site Selection by Unconventional Radical S-Adenosylmethionine Enzymes in Diphthamide Biosynthesis.
    Dong M; Horitani M; Dzikovski B; Freed JH; Ealick SE; Hoffman BM; Lin H
    J Am Chem Soc; 2017 Apr; 139(16):5680-5683. PubMed ID: 28383907
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Elusive 5'-Deoxyadenosyl Radical: Captured and Characterized by Electron Paramagnetic Resonance and Electron Nuclear Double Resonance Spectroscopies.
    Yang H; McDaniel EC; Impano S; Byer AS; Jodts RJ; Yokoyama K; Broderick WE; Broderick JB; Hoffman BM
    J Am Chem Soc; 2019 Jul; 141(30):12139-12146. PubMed ID: 31274303
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Why Nature Uses Radical SAM Enzymes so Widely: Electron Nuclear Double Resonance Studies of Lysine 2,3-Aminomutase Show the 5'-dAdo• "Free Radical" Is Never Free.
    Horitani M; Byer AS; Shisler KA; Chandra T; Broderick JB; Hoffman BM
    J Am Chem Soc; 2015 Jun; 137(22):7111-21. PubMed ID: 25923449
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Radical SAM catalysis via an organometallic intermediate with an Fe-[5'-C]-deoxyadenosyl bond.
    Horitani M; Shisler K; Broderick WE; Hutcheson RU; Duschene KS; Marts AR; Hoffman BM; Broderick JB
    Science; 2016 May; 352(6287):822-5. PubMed ID: 27174986
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization by ENDOR Spectroscopy of the Iron-Alkyl Bond in a Synthetic Counterpart of Organometallic Intermediates in Radical SAM Enzymes.
    Ho MB; Jodts RJ; Kim Y; McSkimming A; Suess DLM; Hoffman BM
    J Am Chem Soc; 2022 Sep; 144(38):17642-17650. PubMed ID: 36108299
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Coordination and mechanism of reversible cleavage of S-adenosylmethionine by the [4Fe-4S] center in lysine 2,3-aminomutase.
    Chen D; Walsby C; Hoffman BM; Frey PA
    J Am Chem Soc; 2003 Oct; 125(39):11788-9. PubMed ID: 14505379
    [TBL] [Abstract][Full Text] [Related]  

  • 18.
    Impano S; Yang H; Shepard EM; Swimley R; Pagnier A; Broderick WE; Hoffman BM; Broderick JB
    Angew Chem Int Ed Engl; 2021 Feb; 60(9):4666-4672. PubMed ID: 33935588
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanism of Reduction of an Aminyl Radical Intermediate in the Radical SAM GTP 3',8-Cyclase MoaA.
    Pang H; Walker LM; Silakov A; Zhang P; Yang W; Elliott SJ; Yokoyama K
    J Am Chem Soc; 2021 Sep; 143(34):13835-13844. PubMed ID: 34423974
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hydrogen transfer in SAM-mediated enzymatic radical reactions.
    Hioe J; Zipse H
    Chemistry; 2012 Dec; 18(51):16463-72. PubMed ID: 23139189
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.