These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

438 related articles for article (PubMed ID: 32968789)

  • 1. Variant-specific changes in persistent or resurgent sodium current in SCN8A-related epilepsy patient-derived neurons.
    Tidball AM; Lopez-Santiago LF; Yuan Y; Glenn TW; Margolis JL; Clayton Walker J; Kilbane EG; Miller CA; Martina Bebin E; Scott Perry M; Isom LL; Parent JM
    Brain; 2020 Oct; 143(10):3025-3040. PubMed ID: 32968789
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Aberrant Sodium Channel Currents and Hyperexcitability of Medial Entorhinal Cortex Neurons in a Mouse Model of
    Ottolini M; Barker BS; Gaykema RP; Meisler MH; Patel MK
    J Neurosci; 2017 Aug; 37(32):7643-7655. PubMed ID: 28676574
    [No Abstract]   [Full Text] [Related]  

  • 3. Prax330 reduces persistent and resurgent sodium channel currents and neuronal hyperexcitability of subiculum neurons in a mouse model of SCN8A epileptic encephalopathy.
    Wengert ER; Saga AU; Panchal PS; Barker BS; Patel MK
    Neuropharmacology; 2019 Nov; 158():107699. PubMed ID: 31278928
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The novel sodium channel modulator GS-458967 (GS967) is an effective treatment in a mouse model of SCN8A encephalopathy.
    Baker EM; Thompson CH; Hawkins NA; Wagnon JL; Wengert ER; Patel MK; George AL; Meisler MH; Kearney JA
    Epilepsia; 2018 Jun; 59(6):1166-1176. PubMed ID: 29782051
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Somatostatin-Positive Interneurons Contribute to Seizures in
    Wengert ER; Miralles RM; Wedgwood KCA; Wagley PK; Strohm SM; Panchal PS; Idrissi AM; Wenker IC; Thompson JA; Gaykema RP; Patel MK
    J Neurosci; 2021 Nov; 41(44):9257-9273. PubMed ID: 34544834
    [No Abstract]   [Full Text] [Related]  

  • 6. Neuronal hyperexcitability in a mouse model of
    Lopez-Santiago LF; Yuan Y; Wagnon JL; Hull JM; Frasier CR; O'Malley HA; Meisler MH; Isom LL
    Proc Natl Acad Sci U S A; 2017 Feb; 114(9):2383-2388. PubMed ID: 28193882
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NBI-921352, a first-in-class, Na
    Johnson JP; Focken T; Khakh K; Tari PK; Dube C; Goodchild SJ; Andrez JC; Bankar G; Bogucki D; Burford K; Chang E; Chowdhury S; Dean R; de Boer G; Decker S; Dehnhardt C; Feng M; Gong W; Grimwood M; Hasan A; Hussainkhel A; Jia Q; Lee S; Li J; Lin S; Lindgren A; Lofstrand V; Mezeyova J; Namdari R; Nelkenbrecher K; Shuart NG; Sojo L; Sun S; Taron M; Waldbrook M; Weeratunge D; Wesolowski S; Williams A; Wilson M; Xie Z; Yoo R; Young C; Zenova A; Zhang W; Cutts AJ; Sherrington RP; Pimstone SN; Winquist R; Cohen CJ; Empfield JR
    Elife; 2022 Mar; 11():. PubMed ID: 35234610
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Distinct functional alterations in SCN8A epilepsy mutant channels.
    Pan Y; Cummins TR
    J Physiol; 2020 Jan; 598(2):381-401. PubMed ID: 31715021
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Complex biophysical changes and reduced neuronal firing in an SCN8A variant associated with developmental delay and epilepsy.
    Quinn S; Zhang N; Fenton TA; Brusel M; Muruganandam P; Peleg Y; Giladi M; Haitin Y; Lerche H; Bassan H; Liu Y; Ben-Shalom R; Rubinstein M
    Biochim Biophys Acta Mol Basis Dis; 2024 Jun; 1870(5):167127. PubMed ID: 38519006
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel de novo mutation of SCN8A (Nav1.6) with enhanced channel activation in a child with epileptic encephalopathy.
    Estacion M; O'Brien JE; Conravey A; Hammer MF; Waxman SG; Dib-Hajj SD; Meisler MH
    Neurobiol Dis; 2014 Sep; 69():117-23. PubMed ID: 24874546
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Aberrant epilepsy-associated mutant Nav1.6 sodium channel activity can be targeted with cannabidiol.
    Patel RR; Barbosa C; Brustovetsky T; Brustovetsky N; Cummins TR
    Brain; 2016 Aug; 139(Pt 8):2164-81. PubMed ID: 27267376
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phenotypic and genetic spectrum of SCN8A-related disorders, treatment options, and outcomes.
    Gardella E; Møller RS
    Epilepsia; 2019 Dec; 60 Suppl 3():S77-S85. PubMed ID: 31904124
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genotype-phenotype correlations in SCN8A-related disorders reveal prognostic and therapeutic implications.
    Johannesen KM; Liu Y; Koko M; Gjerulfsen CE; Sonnenberg L; Schubert J; Fenger CD; Eltokhi A; Rannap M; Koch NA; Lauxmann S; Krüger J; Kegele J; Canafoglia L; Franceschetti S; Mayer T; Rebstock J; Zacher P; Ruf S; Alber M; Sterbova K; Lassuthová P; Vlckova M; Lemke JR; Platzer K; Krey I; Heine C; Wieczorek D; Kroell-Seger J; Lund C; Klein KM; Au PYB; Rho JM; Ho AW; Masnada S; Veggiotti P; Giordano L; Accorsi P; Hoei-Hansen CE; Striano P; Zara F; Verhelst H; Verhoeven JS; Braakman HMH; van der Zwaag B; Harder AVE; Brilstra E; Pendziwiat M; Lebon S; Vaccarezza M; Le NM; Christensen J; Grønborg S; Scherer SW; Howe J; Fazeli W; Howell KB; Leventer R; Stutterd C; Walsh S; Gerard M; Gerard B; Matricardi S; Bonardi CM; Sartori S; Berger A; Hoffman-Zacharska D; Mastrangelo M; Darra F; Vøllo A; Motazacker MM; Lakeman P; Nizon M; Betzler C; Altuzarra C; Caume R; Roubertie A; Gélisse P; Marini C; Guerrini R; Bilan F; Tibussek D; Koch-Hogrebe M; Perry MS; Ichikawa S; Dadali E; Sharkov A; Mishina I; Abramov M; Kanivets I; Korostelev S; Kutsev S; Wain KE; Eisenhauer N; Wagner M; Savatt JM; Müller-Schlüter K; Bassan H; Borovikov A; Nassogne MC; Destrée A; Schoonjans AS; Meuwissen M; Buzatu M; Jansen A; Scalais E; Srivastava S; Tan WH; Olson HE; Loddenkemper T; Poduri A; Helbig KL; Helbig I; Fitzgerald MP; Goldberg EM; Roser T; Borggraefe I; Brünger T; May P; Lal D; Lederer D; Rubboli G; Heyne HO; Lesca G; Hedrich UBS; Benda J; Gardella E; Lerche H; Møller RS
    Brain; 2022 Sep; 145(9):2991-3009. PubMed ID: 34431999
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Remarkable Phenytoin Sensitivity in 4 Children with SCN8A-related Epilepsy: A Molecular Neuropharmacological Approach.
    Boerma RS; Braun KP; van den Broek MP; van Berkestijn FM; Swinkels ME; Hagebeuk EO; Lindhout D; van Kempen M; Boon M; Nicolai J; de Kovel CG; Brilstra EH; Koeleman BP
    Neurotherapeutics; 2016 Jan; 13(1):192-7. PubMed ID: 26252990
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hyperexcitability and Pharmacological Responsiveness of Cortical Neurons Derived from Human iPSCs Carrying Epilepsy-Associated Sodium Channel Nav1.2-L1342P Genetic Variant.
    Que Z; Olivero-Acosta MI; Zhang J; Eaton M; Tukker AM; Chen X; Wu J; Xie J; Xiao T; Wettschurack K; Yunis L; Shafer JM; Schaber JA; Rochet JC; Bowman AB; Yuan C; Huang Z; Hu CD; Trader DJ; Skarnes WC; Yang Y
    J Neurosci; 2021 Dec; 41(49):10194-10208. PubMed ID: 34716231
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The SCN8A encephalopathy mutation p.Ile1327Val displays elevated sensitivity to the anticonvulsant phenytoin.
    Barker BS; Ottolini M; Wagnon JL; Hollander RM; Meisler MH; Patel MK
    Epilepsia; 2016 Sep; 57(9):1458-66. PubMed ID: 27375106
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The absence of resurgent sodium current in mouse spinal neurons.
    Pan F; Beam KG
    Brain Res; 1999 Dec; 849(1-2):162-8. PubMed ID: 10592298
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biallelic inherited SCN8A variants, a rare cause of SCN8A-related developmental and epileptic encephalopathy.
    Wengert ER; Tronhjem CE; Wagnon JL; Johannesen KM; Petit H; Krey I; Saga AU; Panchal PS; Strohm SM; Lange J; Kamphausen SB; Rubboli G; Lemke JR; Gardella E; Patel MK; Meisler MH; Møller RS
    Epilepsia; 2019 Nov; 60(11):2277-2285. PubMed ID: 31625145
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phenotypic and genetic spectrum in Chinese children with SCN8A-related disorders.
    Hu C; Luo T; Wang Y
    Seizure; 2022 Feb; 95():38-49. PubMed ID: 34979445
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Genetic and clinical features of SCN8A developmental and epileptic encephalopathy.
    Kim HJ; Yang D; Kim SH; Kim B; Kim HD; Lee JS; Choi JR; Lee ST; Kang HC
    Epilepsy Res; 2019 Dec; 158():106222. PubMed ID: 31675620
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.