These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 32969649)

  • 1. Improved Accuracy for Modeling PROTAC-Mediated Ternary Complex Formation and Targeted Protein Degradation
    Drummond ML; Henry A; Li H; Williams CI
    J Chem Inf Model; 2020 Oct; 60(10):5234-5254. PubMed ID: 32969649
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PRosettaC: Rosetta Based Modeling of PROTAC Mediated Ternary Complexes.
    Zaidman D; Prilusky J; London N
    J Chem Inf Model; 2020 Oct; 60(10):4894-4903. PubMed ID: 32976709
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rationalizing PROTAC-Mediated Ternary Complex Formation Using Rosetta.
    Bai N; Miller SA; Andrianov GV; Yates M; Kirubakaran P; Karanicolas J
    J Chem Inf Model; 2021 Mar; 61(3):1368-1382. PubMed ID: 33625214
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In Silico Modeling of PROTAC-Mediated Ternary Complexes: Validation and Application.
    Drummond ML; Williams CI
    J Chem Inf Model; 2019 Apr; 59(4):1634-1644. PubMed ID: 30714732
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Integrative Modeling of PROTAC-Mediated Ternary Complexes.
    Weng G; Li D; Kang Y; Hou T
    J Med Chem; 2021 Nov; 64(21):16271-16281. PubMed ID: 34709816
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystallization of VHL-based PROTAC-induced ternary complexes.
    Wijaya AJ; Farnaby W; Ciulli A
    Methods Enzymol; 2023; 681():241-263. PubMed ID: 36764760
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Kinetic Detection of E3:PROTAC:Target Ternary Complexes Using NanoBRET Technology in Live Cells.
    Mahan SD; Riching KM; Urh M; Daniels DL
    Methods Mol Biol; 2021; 2365():151-171. PubMed ID: 34432243
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PROTAC-Design-Evaluator (PRODE): An Advanced Method for In-Silico PROTAC Design.
    A S BG; Agrawal D; Kulkarni NM; Vetrivel R; Gurram K
    ACS Omega; 2024 Mar; 9(11):12611-12621. PubMed ID: 38524483
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization.
    Schwalm MP; Krämer A; Dölle A; Weckesser J; Yu X; Jin J; Saxena K; Knapp S
    Cell Chem Biol; 2023 Jul; 30(7):753-765.e8. PubMed ID: 37354907
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Benchmarking Methods for PROTAC Ternary Complex Structure Prediction.
    Rovers E; Schapira M
    J Chem Inf Model; 2024 Aug; 64(15):6162-6173. PubMed ID: 39087481
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In Silico Modeling and Scoring of PROTAC-Mediated Ternary Complex Poses.
    Liao J; Nie X; Unarta IC; Ericksen SS; Tang W
    J Med Chem; 2022 Apr; 65(8):6116-6132. PubMed ID: 35412837
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SPR-Measured Dissociation Kinetics of PROTAC Ternary Complexes Influence Target Degradation Rate.
    Roy MJ; Winkler S; Hughes SJ; Whitworth C; Galant M; Farnaby W; Rumpel K; Ciulli A
    ACS Chem Biol; 2019 Mar; 14(3):361-368. PubMed ID: 30721025
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An In Vitro Pull-down Assay of the E3 Ligase:PROTAC:Substrate Ternary Complex to Identify Effective PROTACs.
    Bondeson DP; Smith BE; Buhimschi AD
    Methods Mol Biol; 2021; 2365():135-150. PubMed ID: 34432242
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Monitoring and deciphering protein degradation pathways inside cells.
    Daniels DL; Riching KM; Urh M
    Drug Discov Today Technol; 2019 Apr; 31():61-68. PubMed ID: 31200861
    [TBL] [Abstract][Full Text] [Related]  

  • 15. High Accuracy Prediction of PROTAC Complex Structures.
    Ignatov M; Jindal A; Kotelnikov S; Beglov D; Posternak G; Tang X; Maisonneuve P; Poda G; Batey RA; Sicheri F; Whitty A; Tonge PJ; Vajda S; Kozakov D
    J Am Chem Soc; 2023 Apr; 145(13):7123-7135. PubMed ID: 36961978
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Importance of Three-Body Problems and Protein-Protein Interactions in Proteolysis-Targeting Chimera Modeling: Insights from Molecular Dynamics Simulations.
    Li W; Zhang J; Guo L; Wang Q
    J Chem Inf Model; 2022 Feb; 62(3):523-532. PubMed ID: 35084845
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Uncovering the Kinetic Characteristics and Degradation Preference of PROTAC Systems with Advanced Theoretical Analyses.
    Tang R; Wang Z; Xiang S; Wang L; Yu Y; Wang Q; Deng Q; Hou T; Sun H
    JACS Au; 2023 Jun; 3(6):1775-1789. PubMed ID: 37388700
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Computational methods and key considerations for in silico design of proteolysis targeting chimera (PROTACs).
    Abbas A; Ye F
    Int J Biol Macromol; 2024 Oct; 277(Pt 4):134293. PubMed ID: 39084437
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanistic and Structural Features of PROTAC Ternary Complexes.
    Casement R; Bond A; Craigon C; Ciulli A
    Methods Mol Biol; 2021; 2365():79-113. PubMed ID: 34432240
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase.
    Smith BE; Wang SL; Jaime-Figueroa S; Harbin A; Wang J; Hamman BD; Crews CM
    Nat Commun; 2019 Jan; 10(1):131. PubMed ID: 30631068
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.