144 related articles for article (PubMed ID: 32989257)
1. Increased baseline RASGRP1 signals enhance stem cell fitness during native hematopoiesis.
Karra L; Romero-Moya D; Ksionda O; Krush M; Gu Z; Mues M; Depeille P; Mullighan C; Roose JP
Oncogene; 2020 Nov; 39(45):6920-6934. PubMed ID: 32989257
[TBL] [Abstract][Full Text] [Related]
2. RasGRP1 overexpression in T-ALL increases basal nucleotide exchange on Ras rendering the Ras/PI3K/Akt pathway responsive to protumorigenic cytokines.
Ksionda O; Melton AA; Bache J; Tenhagen M; Bakker J; Harvey R; Winter SS; Rubio I; Roose JP
Oncogene; 2016 Jul; 35(28):3658-68. PubMed ID: 26549032
[TBL] [Abstract][Full Text] [Related]
3. Investigating increased hematopoietic stem cell fitness in a novel mouse model.
Karra L; Roose JP
Small GTPases; 2022 Jan; 13(1):7-13. PubMed ID: 33517841
[TBL] [Abstract][Full Text] [Related]
4. Nras Q61R/+ and Kras-/- cooperate to downregulate Rasgrp1 and promote lympho-myeloid leukemia in early T-cell precursors.
Wen Z; Yun G; Hebert A; Kong G; Ranheim EA; Finn R; Rajagoplan A; Li S; Zhou Y; Yu M; Damnernsawad A; Roose JP; Coon JJ; Wen R; Wang D; Zhang J
Blood; 2021 Jun; 137(23):3259-3271. PubMed ID: 33512434
[TBL] [Abstract][Full Text] [Related]
5. Dysregulated RasGRP1 responds to cytokine receptor input in T cell leukemogenesis.
Hartzell C; Ksionda O; Lemmens E; Coakley K; Yang M; Dail M; Harvey RC; Govern C; Bakker J; Lenstra TL; Ammon K; Boeter A; Winter SS; Loh M; Shannon K; Chakraborty AK; Wabl M; Roose JP
Sci Signal; 2013 Mar; 6(268):ra21. PubMed ID: 23532335
[TBL] [Abstract][Full Text] [Related]
6. Distinct oncogenic Ras signals characterized by profound differences in flux through the RasGDP/RasGTP cycle.
Mues M; Roose JP
Small GTPases; 2017 Jan; 8(1):20-25. PubMed ID: 27159504
[TBL] [Abstract][Full Text] [Related]
7. Aberrant expression of RasGRP1 cooperates with gain-of-function NOTCH1 mutations in T-cell leukemogenesis.
Oki T; Kitaura J; Watanabe-Okochi N; Nishimura K; Maehara A; Uchida T; Komeno Y; Nakahara F; Harada Y; Sonoki T; Harada H; Kitamura T
Leukemia; 2012 May; 26(5):1038-45. PubMed ID: 22116551
[TBL] [Abstract][Full Text] [Related]
8. Oncogenic Kras initiates leukemia in hematopoietic stem cells.
Sabnis AJ; Cheung LS; Dail M; Kang HC; Santaguida M; Hermiston ML; Passegué E; Shannon K; Braun BS
PLoS Biol; 2009 Mar; 7(3):e59. PubMed ID: 19296721
[TBL] [Abstract][Full Text] [Related]
9. Distinct requirements of hematopoietic stem cell activity and Nras G12D signaling in different cell types during leukemogenesis.
Wang J; Liu Y; Tan LX; Lo JC; Du J; Ryu MJ; Ranheim EA; Zhang J
Cell Cycle; 2011 Sep; 10(17):2836-9. PubMed ID: 21857161
[TBL] [Abstract][Full Text] [Related]
10. A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells.
Roose JP; Mollenauer M; Gupta VA; Stone J; Weiss A
Mol Cell Biol; 2005 Jun; 25(11):4426-41. PubMed ID: 15899849
[TBL] [Abstract][Full Text] [Related]
11. Loss of Dnmt3a and endogenous Kras(G12D/+) cooperate to regulate hematopoietic stem and progenitor cell functions in leukemogenesis.
Chang YI; You X; Kong G; Ranheim EA; Wang J; Du J; Liu Y; Zhou Y; Ryu MJ; Zhang J
Leukemia; 2015 Sep; 29(9):1847-56. PubMed ID: 25801914
[TBL] [Abstract][Full Text] [Related]
12. Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus.
Li Q; Haigis KM; McDaniel A; Harding-Theobald E; Kogan SC; Akagi K; Wong JC; Braun BS; Wolff L; Jacks T; Shannon K
Blood; 2011 Feb; 117(6):2022-32. PubMed ID: 21163920
[TBL] [Abstract][Full Text] [Related]
13. The transcription factor Gfi1 regulates G-CSF signaling and neutrophil development through the Ras activator RasGRP1.
de la Luz Sierra M; Sakakibara S; Gasperini P; Salvucci O; Jiang K; McCormick PJ; Segarra M; Stone J; Maric D; Zhu J; Qian X; Lowy DR; Tosato G
Blood; 2010 May; 115(19):3970-9. PubMed ID: 20203268
[TBL] [Abstract][Full Text] [Related]
14. RasGRP1 and RasGRP3 Are Required for Efficient Generation of Early Thymic Progenitors.
Golec DP; Henao Caviedes LM; Baldwin TA
J Immunol; 2016 Sep; 197(5):1743-53. PubMed ID: 27465532
[TBL] [Abstract][Full Text] [Related]
15. Aberrant Notch Signaling in the Bone Marrow Microenvironment of Acute Lymphoid Leukemia Suppresses Osteoblast-Mediated Support of Hematopoietic Niche Function.
Wang W; Zimmerman G; Huang X; Yu S; Myers J; Wang Y; Moreton S; Nthale J; Awadallah A; Beck R; Xin W; Wald D; Huang AY; Zhou L
Cancer Res; 2016 Mar; 76(6):1641-52. PubMed ID: 26801976
[TBL] [Abstract][Full Text] [Related]
16. BRD2 induces drug resistance through activation of the RasGRP1/Ras/ERK signaling pathway in adult T-cell lymphoblastic lymphoma.
Tian XP; Cai J; Ma SY; Fang Y; Huang HQ; Lin TY; Rao HL; Li M; Xia ZJ; Kang TB; Xie D; Cai QQ
Cancer Commun (Lond); 2020 Jun; 40(6):245-259. PubMed ID: 32459053
[TBL] [Abstract][Full Text] [Related]
17. Lhx2 expression in hematopoietic progenitor/stem cells in vivo causes a chronic myeloproliferative disorder and altered globin expression.
Richter K; Pinto do O P; Hägglund AC; Wahlin A; Carlsson L
Haematologica; 2003 Dec; 88(12):1336-47. PubMed ID: 14687986
[TBL] [Abstract][Full Text] [Related]
18. Hematopoietic abnormalities in mice deficient in gp130-mediated STAT signaling.
Jenkins BJ; Quilici C; Roberts AW; Grail D; Dunn AR; Ernst M
Exp Hematol; 2002 Nov; 30(11):1248-56. PubMed ID: 12423677
[TBL] [Abstract][Full Text] [Related]
19. Rasgrp1 mutation increases naive T-cell CD44 expression and drives mTOR-dependent accumulation of Helios⁺ T cells and autoantibodies.
Daley SR; Coakley KM; Hu DY; Randall KL; Jenne CN; Limnander A; Myers DR; Polakos NK; Enders A; Roots C; Balakishnan B; Miosge LA; Sjollema G; Bertram EM; Field MA; Shao Y; Andrews TD; Whittle B; Barnes SW; Walker JR; Cyster JG; Goodnow CC; Roose JP
Elife; 2013 Dec; 2():e01020. PubMed ID: 24336796
[TBL] [Abstract][Full Text] [Related]
20. Single cell proteomics characterization of bone marrow hematopoiesis with distinct Ras pathway lesions.
Karra L; Finger AM; Shechtman L; Krush M; Huang RM; Prinz M; Tennvooren I; Bahl K; Hysienaj L; Gonzalez PG; Combes AJ; Gonzalez H; Argüello RJ; Spitzer MH; Roose JP
bioRxiv; 2023 Dec; ():. PubMed ID: 38187679
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
