BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 32992343)

  • 1. VAV1 mutations contribute to development of T-cell neoplasms in mice.
    Fukumoto K; Sakata-Yanagimoto M; Fujisawa M; Sakamoto T; Miyoshi H; Suehara Y; Nguyen TB; Suma S; Yanagimoto S; Shiraishi Y; Chiba K; Bouska A; Kataoka K; Ogawa S; Iqbal J; Ohshima K; Chiba S
    Blood; 2020 Dec; 136(26):3018-3032. PubMed ID: 32992343
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma.
    Cortes JR; Filip I; Albero R; Patiño-Galindo JA; Quinn SA; Lin WW; Laurent AP; Shih BB; Brown JA; Cooke AJ; Mackey A; Einson J; Zairis S; Rivas-Delgado A; Laginestra MA; Pileri S; Campo E; Bhagat G; Ferrando AA; Rabadan R; Palomero T
    Cell Rep; 2022 Apr; 39(3):110695. PubMed ID: 35443168
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis.
    Robles-Valero J; Fernández-Nevado L; Lorenzo-Martín LF; Cuadrado M; Fernández-Pisonero I; Rodríguez-Fdez S; Astorga-Simón EN; Abad A; Caloto R; Bustelo XR
    EMBO J; 2021 Nov; 40(22):e108125. PubMed ID: 34617326
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The fusion oncogene VAV1-MYO1F triggers aberrant T-cell receptor signaling in vivo and drives peripheral T-cell lymphoma in mice.
    Morrish E; Wartewig T; Kratzert A; Rosenbaum M; Steiger K; Ruland J
    Eur J Immunol; 2023 Mar; 53(3):e2250147. PubMed ID: 36541400
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activating mutations and translocations in the guanine exchange factor VAV1 in peripheral T-cell lymphomas.
    Abate F; da Silva-Almeida AC; Zairis S; Robles-Valero J; Couronne L; Khiabanian H; Quinn SA; Kim MY; Laginestra MA; Kim C; Fiore D; Bhagat G; Piris MA; Campo E; Lossos IS; Bernard OA; Inghirami G; Pileri S; Bustelo XR; Rabadan R; Ferrando AA; Palomero T
    Proc Natl Acad Sci U S A; 2017 Jan; 114(4):764-769. PubMed ID: 28062691
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutation of Vav1 adaptor region reveals a new oncogenic activation.
    Razanadrakoto L; Cormier F; Laurienté V; Dondi E; Gardano L; Katzav S; Guittat L; Varin-Blank N
    Oncotarget; 2015 Feb; 6(4):2524-37. PubMed ID: 25426554
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of the spectrum of trivalent VAV1-mutation-driven tumours using a gene-edited mouse model.
    Robles-Valero J; Fernández-Nevado L; Cuadrado M; Lorenzo-Martín LF; Fernández-Pisonero I; Abad A; Redín E; Montuenga L; Martín-Zanca D; Bigas A; Mallo M; Dosil M; Bustelo XR
    Mol Oncol; 2022 Oct; 16(19):3533-3553. PubMed ID: 35895495
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Genetic alterations in new category of Peripheral T-cell lymphoma, not otherwise specified].
    Fukumoto K
    Rinsho Ketsueki; 2022; 63(12):1657-1667. PubMed ID: 36653140
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Unraveling the Oncogenic Potential of VAV1 in Human Cancer: Lessons from Mouse Models.
    Shalom B; Salaymeh Y; Risling M; Katzav S
    Cells; 2023 Apr; 12(9):. PubMed ID: 37174676
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Oncogenic Vav1 induces Rac-dependent apoptosis via inhibition of Bcl-2 family proteins and collaborates with p53 deficiency to promote hematopoietic progenitor cell proliferation.
    Gu Y; Siefring JE; Wang L; Chae HD; Bailey JR; Zheng Y
    Oncogene; 2006 Jun; 25(28):3963-72. PubMed ID: 16474842
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tyrosine residues at the carboxyl terminus of Vav1 play an important role in regulation of its biological activity.
    Lazer G; Pe'er L; Farago M; Machida K; Mayer BJ; Katzav S
    J Biol Chem; 2010 Jul; 285(30):23075-85. PubMed ID: 20457609
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Vav1 fine tunes p53 control of apoptosis versus proliferation in breast cancer.
    Sebban S; Farago M; Gashai D; Ilan L; Pikarsky E; Ben-Porath I; Katzav S
    PLoS One; 2013; 8(1):e54321. PubMed ID: 23342133
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of RHOA-VAV1 signaling in angioimmunoblastic T-cell lymphoma.
    Fujisawa M; Sakata-Yanagimoto M; Nishizawa S; Komori D; Gershon P; Kiryu M; Tanzima S; Fukumoto K; Enami T; Muratani M; Yoshida K; Ogawa S; Matsue K; Nakamura N; Takeuchi K; Izutsu K; Fujimoto K; Teshima T; Miyoshi H; Gaulard P; Ohshima K; Chiba S
    Leukemia; 2018 Mar; 32(3):694-702. PubMed ID: 28832024
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The association of Sam68 with Vav1 contributes to tumorigenesis.
    Lazer G; Pe'er L; Schapira V; Richard S; Katzav S
    Cell Signal; 2007 Dec; 19(12):2479-86. PubMed ID: 17855053
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Osteopontin is an oncogenic Vav1- but not wild-type Vav1-responsive gene: implications for fibroblast transformation.
    Schapira V; Lazer G; Katzav S
    Cancer Res; 2006 Jun; 66(12):6183-91. PubMed ID: 16778192
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Vav1 and mutant K-Ras synergize in the early development of pancreatic ductal adenocarcinoma in mice.
    Salaymeh Y; Farago M; Sebban S; Shalom B; Pikarsky E; Katzav S
    Life Sci Alliance; 2020 May; 3(5):. PubMed ID: 32277014
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Function of the nucleotide exchange activity of vav1 in T cell development and activation.
    Saveliev A; Vanes L; Ksionda O; Rapley J; Smerdon SJ; Rittinger K; Tybulewicz VL
    Sci Signal; 2009 Dec; 2(101):ra83. PubMed ID: 20009105
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The N-terminal 20-amino acid region of guanine nucleotide exchange factor Vav1 plays a distinguished role in T cell receptor-mediated calcium signaling.
    Li SY; Du MJ; Wan YJ; Lan B; Liu YH; Yang Y; Zhang CZ; Cao Y
    J Biol Chem; 2013 Feb; 288(6):3777-85. PubMed ID: 23271736
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The use of knockout mice reveals a synergistic role of the Vav1 and Rasgrf2 gene deficiencies in lymphomagenesis and metastasis.
    Ruiz S; Santos E; Bustelo XR
    PLoS One; 2009 Dec; 4(12):e8229. PubMed ID: 20011522
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Guanine nucleotide exchange factor Vav1 regulates perivascular homing and bone marrow retention of hematopoietic stem and progenitor cells.
    Sanchez-Aguilera A; Lee YJ; Lo Celso C; Ferraro F; Brumme K; Mondal S; Kim C; Dorrance A; Luo HR; Scadden DT; Williams DA
    Proc Natl Acad Sci U S A; 2011 Jun; 108(23):9607-12. PubMed ID: 21606370
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.