BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

322 related articles for article (PubMed ID: 32992716)

  • 1. Presenilin-2 and Calcium Handling: Molecules, Organelles, Cells and Brain Networks.
    Pizzo P; Basso E; Filadi R; Greotti E; Leparulo A; Pendin D; Redolfi N; Rossini M; Vajente N; Pozzan T; Fasolato C
    Cells; 2020 Sep; 9(10):. PubMed ID: 32992716
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Familial Alzheimer's disease-linked presenilin mutants and intracellular Ca
    Greotti E; Capitanio P; Wong A; Pozzan T; Pizzo P; Pendin D
    Cell Calcium; 2019 May; 79():44-56. PubMed ID: 30822648
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Calcium Signaling and Mitochondrial Function in Presenilin 2 Knock-Out Mice: Looking for Any Loss-of-Function Phenotype Related to Alzheimer's Disease.
    Rossi A; Galla L; Gomiero C; Zentilin L; Giacca M; Giorgio V; Calì T; Pozzan T; Greotti E; Pizzo P
    Cells; 2021 Jan; 10(2):. PubMed ID: 33494218
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Intracellular Calcium Dysregulation by the Alzheimer's Disease-Linked Protein Presenilin 2.
    Galla L; Redolfi N; Pozzan T; Pizzo P; Greotti E
    Int J Mol Sci; 2020 Jan; 21(3):. PubMed ID: 31991578
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Familial Alzheimer's disease presenilin-2 mutants affect Ca
    Pendin D; Fasolato C; Basso E; Filadi R; Greotti E; Galla L; Gomiero C; Leparulo A; Redolfi N; Scremin E; Vajente N; Pozzan T; Pizzo P
    Aging Clin Exp Res; 2021 Jun; 33(6):1705-1708. PubMed ID: 31606858
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loosening ER-Mitochondria Coupling by the Expression of the Presenilin 2 Loop Domain.
    Rossini M; García-Casas P; Filadi R; Pizzo P
    Cells; 2021 Aug; 10(8):. PubMed ID: 34440738
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Presenilin Is Essential for ApoE Secretion, a Novel Role of Presenilin Involved in Alzheimer's Disease Pathogenesis.
    Islam S; Sun Y; Gao Y; Nakamura T; Noorani AA; Li T; Wong PC; Kimura N; Matsubara E; Kasuga K; Ikeuchi T; Tomita T; Zou K; Michikawa M
    J Neurosci; 2022 Feb; 42(8):1574-1586. PubMed ID: 34987110
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thapsigargin affects presenilin-2 but not presenilin-1 regulation in SK-N-BE cells.
    Rivabene R; Visentin S; Piscopo P; De Nuccio C; Crestini A; Svetoni F; Rosa P; Confaloni A
    Exp Biol Med (Maywood); 2014 Feb; 239(2):213-24. PubMed ID: 24363250
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Attenuated presenilin-1 endoproteolysis enhances store-operated calcium currents in neuronal cells.
    Ryazantseva M; Skobeleva K; Glushankova L; Kaznacheyeva E
    J Neurochem; 2016 Mar; 136(5):1085-95. PubMed ID: 26678016
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels.
    Zatti G; Burgo A; Giacomello M; Barbiero L; Ghidoni R; Sinigaglia G; Florean C; Bagnoli S; Binetti G; Sorbi S; Pizzo P; Fasolato C
    Cell Calcium; 2006 Jun; 39(6):539-50. PubMed ID: 16620965
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Generation of Abeta38 and Abeta42 is independently and differentially affected by familial Alzheimer disease-associated presenilin mutations and gamma-secretase modulation.
    Page RM; Baumann K; Tomioka M; Pérez-Revuelta BI; Fukumori A; Jacobsen H; Flohr A; Luebbers T; Ozmen L; Steiner H; Haass C
    J Biol Chem; 2008 Jan; 283(2):677-83. PubMed ID: 17962197
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pathological activity of familial Alzheimer's disease-associated mutant presenilin can be executed by six different gamma-secretase complexes.
    Shirotani K; Tomioka M; Kremmer E; Haass C; Steiner H
    Neurobiol Dis; 2007 Jul; 27(1):102-7. PubMed ID: 17560791
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Quantitative comparison of presenilin protein expression reveals greater activity of PS2-γ-secretase.
    Eccles MK; Main N; Carlessi R; Armstrong AM; Sabale M; Roberts-Mok B; Tirnitz-Parker JEE; Agostino M; Groth D; Fraser PE; Verdile G
    FASEB J; 2024 Jan; 38(1):e23396. PubMed ID: 38156414
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PSEN2 (presenilin 2) mutants linked to familial Alzheimer disease impair autophagy by altering Ca
    Fedeli C; Filadi R; Rossi A; Mammucari C; Pizzo P
    Autophagy; 2019 Dec; 15(12):2044-2062. PubMed ID: 30892128
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Conformational Models of APP Processing by Gamma Secretase Based on Analysis of Pathogenic Mutations.
    Kim M; Bezprozvanny I
    Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34948396
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Alzheimer's disease-linked mutations in presenilin-1 result in a drastic loss of activity in purified γ-secretase complexes.
    Cacquevel M; Aeschbach L; Houacine J; Fraering PC
    PLoS One; 2012; 7(4):e35133. PubMed ID: 22529981
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pen2 and presenilin-1 modulate the dynamic equilibrium of presenilin-1 and presenilin-2 gamma-secretase complexes.
    Placanica L; Tarassishin L; Yang G; Peethumnongsin E; Kim SH; Zheng H; Sisodia SS; Li YM
    J Biol Chem; 2009 Jan; 284(5):2967-2977. PubMed ID: 19036728
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Familial Alzheimer's disease-associated presenilin 1 mutants promote γ-secretase cleavage of STIM1 to impair store-operated Ca2+ entry.
    Tong BC; Lee CS; Cheng WH; Lai KO; Foskett JK; Cheung KH
    Sci Signal; 2016 Sep; 9(444):ra89. PubMed ID: 27601731
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Different transmembrane domains determine the specificity and efficiency of the cleavage activity of the γ-secretase subunit presenilin.
    Schmidt FC; Fitz K; Feilen LP; Okochi M; Steiner H; Langosch D
    J Biol Chem; 2023 May; 299(5):104626. PubMed ID: 36944398
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations.
    Tu H; Nelson O; Bezprozvanny A; Wang Z; Lee SF; Hao YH; Serneels L; De Strooper B; Yu G; Bezprozvanny I
    Cell; 2006 Sep; 126(5):981-93. PubMed ID: 16959576
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.