BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 33003585)

  • 1. Exploiting Chromosomal Instability of PTEN-Deficient Triple-Negative Breast Cancer Cell Lines for the Sensitization against PARP1 Inhibition in a Replication-Dependent Manner.
    Rieckhoff J; Meyer F; Classen S; Zielinski A; Riepen B; Wikman H; Petersen C; Rothkamm K; Borgmann K; Parplys AC
    Cancers (Basel); 2020 Sep; 12(10):. PubMed ID: 33003585
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), enhances anti-tumor effects of the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib in triple-negative breast cancer cells.
    Min A; Im SA; Kim DK; Song SH; Kim HJ; Lee KH; Kim TY; Han SW; Oh DY; Kim TY; O'Connor MJ; Bang YJ
    Breast Cancer Res; 2015 Mar; 17():33. PubMed ID: 25888415
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Using next-generation sequencing to redefine BRCAness in triple-negative breast cancer.
    Lin PH; Chen M; Tsai LW; Lo C; Yen TC; Huang TY; Chen CK; Fan SC; Kuo SH; Huang CS
    Cancer Sci; 2020 Apr; 111(4):1375-1384. PubMed ID: 31958182
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The oncoprotein DEK affects the outcome of PARP1/2 inhibition during mild replication stress.
    Ganz M; Vogel C; Czada C; Jörke V; Gwosch EC; Kleiner R; Pierzynska-Mach A; Zanacchi FC; Diaspro A; Kappes F; Bürkle A; Ferrando-May E
    PLoS One; 2019; 14(8):e0213130. PubMed ID: 31408463
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Co-targeting poly(ADP-ribose) polymerase (PARP) and histone deacetylase (HDAC) in triple-negative breast cancer: Higher synergism in BRCA mutated cells.
    Marijon H; Lee DH; Ding L; Sun H; Gery S; de Gramont A; Koeffler HP
    Biomed Pharmacother; 2018 Mar; 99():543-551. PubMed ID: 29902865
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MicroRNA-498 promotes proliferation and migration by targeting the tumor suppressor PTEN in breast cancer cells.
    Chai C; Wu H; Wang B; Eisenstat DD; Leng RP
    Carcinogenesis; 2018 Sep; 39(9):1185-1196. PubMed ID: 29985991
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer.
    Al-Ejeh F; Simpson PT; Sanus JM; Klein K; Kalimutho M; Shi W; Miranda M; Kutasovic J; Raghavendra A; Madore J; Reid L; Krause L; Chenevix-Trench G; Lakhani SR; Khanna KK
    Oncogenesis; 2014 Apr; 3(4):e100. PubMed ID: 24752235
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Correlation Between PARP1 and BRCA1 in AR Positive Triple-negative Breast Cancer.
    Luo J; Jin J; Yang F; Sun Z; Zhang W; Shi Y; Xu J; Guan X
    Int J Biol Sci; 2016; 12(12):1500-1510. PubMed ID: 27994514
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Upregulation of Poly (ADP-Ribose) Polymerase-1 (PARP1) in Triple-Negative Breast Cancer and Other Primary Human Tumor Types.
    Ossovskaya V; Koo IC; Kaldjian EP; Alvares C; Sherman BM
    Genes Cancer; 2010 Aug; 1(8):812-21. PubMed ID: 21779467
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Treatment of PTEN-Null Breast Cancer by a Synthetic Lethal Approach Involving PARP1 Gene Silencing.
    Asai T; Yokota M; Isomura H; Koide H; Sakurai N; Okamoto A; Ando H; Dewa T; Oku N
    J Pharm Sci; 2023 Jul; 112(7):1908-1914. PubMed ID: 36828124
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting ataxia telangiectasia-mutated- and Rad3-related kinase (ATR) in PTEN-deficient breast cancers for personalized therapy.
    Al-Subhi N; Ali R; Abdel-Fatah T; Moseley PM; Chan SYT; Green AR; Ellis IO; Rakha EA; Madhusudan S
    Breast Cancer Res Treat; 2018 Jun; 169(2):277-286. PubMed ID: 29396668
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Triptolide interferes with XRCC1/PARP1-mediated DNA repair and confers sensitization of triple-negative breast cancer cells to cisplatin.
    Zhang Z; Sun C; Zhang L; Chi X; Ji J; Gao X; Wang Y; Zhao Z; Liu L; Cao X; Yang Y; Mao W
    Biomed Pharmacother; 2019 Jan; 109():1541-1546. PubMed ID: 30551406
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BRCA Gene Mutations and Poly(ADP-Ribose) Polymerase Inhibitors in Triple-Negative Breast Cancer.
    Okuma HS; Yonemori K
    Adv Exp Med Biol; 2017; 1026():271-286. PubMed ID: 29282689
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Class I histone deacetylase inhibitor suppresses vasculogenic mimicry by enhancing the expression of tumor suppressor and anti-angiogenesis genes in aggressive human TNBC cells.
    Maiti A; Qi Q; Peng X; Yan L; Takabe K; Hait NC
    Int J Oncol; 2019 Jul; 55(1):116-130. PubMed ID: 31059004
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of BRCA1-like triple-negative breast cancers by quantitative multiplex-ligation-dependent probe amplification (MLPA) analysis of BRCA1-associated chromosomal regions: a validation study.
    Gross E; van Tinteren H; Li Z; Raab S; Meul C; Avril S; Laddach N; Aubele M; Propping C; Gkazepis A; Schmitt M; Meindl A; Nederlof PM; Kiechle M; Lips EH
    BMC Cancer; 2016 Oct; 16(1):811. PubMed ID: 27756336
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A subgroup of microRNAs defines PTEN-deficient, triple-negative breast cancer patients with poorest prognosis and alterations in RB1, MYC, and Wnt signaling.
    Wang DY; Gendoo DMA; Ben-David Y; Woodgett JR; Zacksenhaus E
    Breast Cancer Res; 2019 Jan; 21(1):18. PubMed ID: 30704524
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel crosstalk between BRCA1 and poly (ADP-ribose) polymerase 1 in breast cancer.
    Li D; Bi FF; Chen NN; Cao JM; Sun WP; Zhou YM; Li CY; Yang Q
    Cell Cycle; 2014; 13(21):3442-9. PubMed ID: 25485588
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MUC1-C Integrates Chromatin Remodeling and PARP1 Activity in the DNA Damage Response of Triple-Negative Breast Cancer Cells.
    Yamamoto M; Jin C; Hata T; Yasumizu Y; Zhang Y; Hong D; Maeda T; Miyo M; Hiraki M; Suzuki Y; Hinohara K; Rajabi H; Kufe D
    Cancer Res; 2019 Apr; 79(8):2031-2041. PubMed ID: 30824588
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PTEN regulates RPA1 and protects DNA replication forks.
    Wang G; Li Y; Wang P; Liang H; Cui M; Zhu M; Guo L; Su Q; Sun Y; McNutt MA; Yin Y
    Cell Res; 2015 Nov; 25(11):1189-204. PubMed ID: 26403191
    [TBL] [Abstract][Full Text] [Related]  

  • 20. INPP4B and PTEN Loss Leads to PI-3,4-P2 Accumulation and Inhibition of PI3K in TNBC.
    Reed DE; Shokat KM
    Mol Cancer Res; 2017 Jun; 15(6):765-775. PubMed ID: 28196852
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.