124 related articles for article (PubMed ID: 33006903)
21. Integrative genomic analyses on GLI1: positive regulation of GLI1 by Hedgehog-GLI, TGFbeta-Smads, and RTK-PI3K-AKT signals, and negative regulation of GLI1 by Notch-CSL-HES/HEY, and GPCR-Gs-PKA signals.
Katoh Y; Katoh M
Int J Oncol; 2009 Jul; 35(1):187-92. PubMed ID: 19513567
[TBL] [Abstract][Full Text] [Related]
22. Targeting GLI proteins in human cancer by small molecules (WO2014116651 A1): a patent evaluation.
Hadden MK
Expert Opin Ther Pat; 2015 May; 25(5):613-7. PubMed ID: 25772316
[TBL] [Abstract][Full Text] [Related]
23. Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors.
Infante P; Mori M; Alfonsi R; Ghirga F; Aiello F; Toscano S; Ingallina C; Siler M; Cucchi D; Po A; Miele E; D'Amico D; Canettieri G; De Smaele E; Ferretti E; Screpanti I; Uccello Barretta G; Botta M; Botta B; Gulino A; Di Marcotullio L
EMBO J; 2015 Jan; 34(2):200-17. PubMed ID: 25476449
[TBL] [Abstract][Full Text] [Related]
24. Structure-based virtual screening identifies an 8-hydroxyquinoline as a small molecule GLI1 inhibitor.
Dash RC; Wen J; Zaino AM; Morel SR; Chau LQ; Wechsler-Reya RJ; Hadden MK
Mol Ther Oncolytics; 2021 Mar; 20():265-276. PubMed ID: 33614910
[TBL] [Abstract][Full Text] [Related]
25. PI3K/Akt/mTOR and Ras/Raf/MEK/ERK signaling pathways inhibitors as anticancer agents: Structural and pharmacological perspectives.
Asati V; Mahapatra DK; Bharti SK
Eur J Med Chem; 2016 Feb; 109():314-41. PubMed ID: 26807863
[TBL] [Abstract][Full Text] [Related]
26. Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression.
Tang CM; Lee TE; Syed SA; Burgoyne AM; Leonard SY; Gao F; Chan JC; Shi E; Chmielecki J; Morosini D; Wang K; Ross JS; Kendrick ML; Bardsley MR; Siena M; Mao J; Harismendy O; Ordog T; Sicklick JK
Oncotarget; 2016 Nov; 7(48):78226-78241. PubMed ID: 27793025
[TBL] [Abstract][Full Text] [Related]
27. Aberrant activation of hedgehog signaling promotes cell proliferation via the transcriptional activation of forkhead Box M1 in colorectal cancer cells.
Wang D; Hu G; Du Y; Zhang C; Lu Q; Lv N; Luo S
J Exp Clin Cancer Res; 2017 Feb; 36(1):23. PubMed ID: 28148279
[TBL] [Abstract][Full Text] [Related]
28. Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.
Stecca B; Mas C; Clement V; Zbinden M; Correa R; Piguet V; Beermann F; Ruiz i Altaba A
Proc Natl Acad Sci U S A; 2007 Apr; 104(14):5895-900. PubMed ID: 17392427
[TBL] [Abstract][Full Text] [Related]
29. Cross-talk between GLI transcription factors and FOXC1 promotes T-cell acute lymphoblastic leukemia dissemination.
Tosello V; Bongiovanni D; Liu J; Pan Q; Yan KK; Saccomani V; Van Trimpont M; Pizzi M; Mazzoni M; Dei Tos AP; Amadori A; Zanovello P; Van Vlierberghe P; Yu J; Piovan E
Leukemia; 2021 Apr; 35(4):984-1000. PubMed ID: 32733009
[TBL] [Abstract][Full Text] [Related]
30. GLI1 Blockade Potentiates the Antitumor Activity of PI3K Antagonists in Lung Squamous Cell Carcinoma.
Kasiri S; Shao C; Chen B; Wilson AN; Yenerall P; Timmons BC; Girard L; Tian H; Behrens C; Wistuba II; Gazdar AF; Kim J
Cancer Res; 2017 Aug; 77(16):4448-4459. PubMed ID: 28652248
[TBL] [Abstract][Full Text] [Related]
31. Nanoquinacrine induced apoptosis in cervical cancer stem cells through the inhibition of hedgehog-GLI1 cascade: Role of GLI-1.
Nayak A; Satapathy SR; Das D; Siddharth S; Tripathi N; Bharatam PV; Kundu C
Sci Rep; 2016 Feb; 6():20600. PubMed ID: 26846872
[TBL] [Abstract][Full Text] [Related]
32. Hedgehog signaling and the Gli code in stem cells, cancer, and metastases.
Ruiz i Altaba A
Sci Signal; 2011 Nov; 4(200):pt9. PubMed ID: 22114144
[TBL] [Abstract][Full Text] [Related]
33. Targeting hedgehog signaling pathway in pediatric tumors: in vitro evaluation of SMO and GLI inhibitors.
Arnhold V; Boos J; Lanvers-Kaminsky C
Cancer Chemother Pharmacol; 2016 Mar; 77(3):495-505. PubMed ID: 26781311
[TBL] [Abstract][Full Text] [Related]
34. Hedgehog signalling mediates drug resistance through targeting TAP1 in hepatocellular carcinoma.
Zhou XT; Ding J; Li HY; Zuo JL; Ge SY; Jia HL; Wu J
J Cell Mol Med; 2020 Apr; 24(7):4298-4311. PubMed ID: 32108992
[TBL] [Abstract][Full Text] [Related]
35. Crosstalk between Hedgehog pathway and the glucocorticoid receptor pathway as a basis for combination therapy in T-cell acute lymphoblastic leukemia.
Bongiovanni D; Tosello V; Saccomani V; Dalla Santa S; Amadori A; Zanovello P; Piovan E
Oncogene; 2020 Oct; 39(42):6544-6555. PubMed ID: 32917954
[TBL] [Abstract][Full Text] [Related]
36. ErbB2 signaling activates the Hedgehog pathway via PI3K-Akt in human esophageal adenocarcinoma: identification of novel targets for concerted therapy concepts.
Kebenko M; Drenckhan A; Gros SJ; Jücker M; Grabinski N; Ewald F; Grottke A; Schultze A; Izbicki JR; Bokemeyer C; Wellbrock J; Fiedler W
Cell Signal; 2015 Feb; 27(2):373-81. PubMed ID: 25435423
[TBL] [Abstract][Full Text] [Related]
37. Recent development of targeted approaches for the treatment of breast cancer.
Maruthanila VL; Elancheran R; Kunnumakkara AB; Kabilan S; Kotoky J
Breast Cancer; 2017 Mar; 24(2):191-219. PubMed ID: 27796923
[TBL] [Abstract][Full Text] [Related]
38. GLI1-mediated regulation of side population is responsible for drug resistance in gastric cancer.
Yu B; Gu D; Zhang X; Li J; Liu B; Xie J
Oncotarget; 2017 Apr; 8(16):27412-27427. PubMed ID: 28404967
[TBL] [Abstract][Full Text] [Related]
39. Targeting the PI3K/AKT pathway via GLI1 inhibition enhanced the drug sensitivity of acute myeloid leukemia cells.
Liang H; Zheng QL; Fang P; Zhang J; Zhang T; Liu W; Guo M; Robinson CL; Chen SB; Chen XP; Chen FP; Zeng H
Sci Rep; 2017 Jan; 7():40361. PubMed ID: 28098170
[TBL] [Abstract][Full Text] [Related]
40. Up-regulation of GLI1 in vincristine-resistant rhabdomyosarcoma and Ewing sarcoma.
Yoon JW; Lamm M; Chandler C; Iannaccone P; Walterhouse D
BMC Cancer; 2020 Jun; 20(1):511. PubMed ID: 32493277
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]