These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 33016117)

  • 1. Recent advances in the development of elastase inhibitors.
    Donarska B; Z Łączkowski K
    Future Med Chem; 2020 Oct; 12(20):1809-1813. PubMed ID: 33016117
    [No Abstract]   [Full Text] [Related]  

  • 2. Design, synthesis, and in vitro evaluation of inhibitors of human leukocyte elastase based on a functionalized cyclic sulfamide scaffold.
    Zhong J; Gan X; Alliston KR; Groutas WC
    Bioorg Med Chem; 2004 Feb; 12(3):589-93. PubMed ID: 14738969
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and optimization of 2-pyridin-3-yl-benzo[d][1,3]oxazin-4-one based inhibitors of human neutrophil elastase.
    Shreder KR; Cajica J; Du L; Fraser A; Hu Y; Kohno Y; Lin EC; Liu SJ; Okerberg E; Pham L; Wu J; Kozarich JW
    Bioorg Med Chem Lett; 2009 Aug; 19(16):4743-6. PubMed ID: 19577470
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Isoxazol-5(2H)-one: a new scaffold for potent human neutrophil elastase (HNE) inhibitors.
    Vergelli C; Schepetkin IA; Crocetti L; Iacovone A; Giovannoni MP; Guerrini G; Khlebnikov AI; Ciattini S; Ciciani G; Quinn MT
    J Enzyme Inhib Med Chem; 2017 Dec; 32(1):821-831. PubMed ID: 28612630
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Neutrophil elastase inhibitors: recent advances in the development of mechanism-based and nonelectrophilic inhibitors.
    Sjö P
    Future Med Chem; 2012 Apr; 4(5):651-60. PubMed ID: 22458683
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of human leukocyte elastase by brunsvicamides a-C: cyanobacterial cyclic peptides.
    Sisay MT; Hautmann S; Mehner C; König GM; Bajorath J; Gütschow M
    ChemMedChem; 2009 Sep; 4(9):1425-9. PubMed ID: 19569166
    [No Abstract]   [Full Text] [Related]  

  • 7. Exploration of nitrogen heterocycle scaffolds for the development of potent human neutrophil elastase inhibitors.
    Cantini N; Khlebnikov AI; Crocetti L; Schepetkin IA; Floresta G; Guerrini G; Vergelli C; Bartolucci G; Quinn MT; Giovannoni MP
    Bioorg Med Chem; 2021 Jan; 29():115836. PubMed ID: 33218895
    [TBL] [Abstract][Full Text] [Related]  

  • 8. N-Acyl and N-sulfonyloxazolidine-2,4-diones are pseudo-irreversible inhibitors of serine proteases.
    Santana AB; Lucas SD; Gonçalves LM; Correia HF; Cardote TA; Guedes RC; Iley J; Moreira R
    Bioorg Med Chem Lett; 2012 Jun; 22(12):3993-7. PubMed ID: 22595175
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase.
    Zheng Q; Woehl JL; Kitamura S; Santos-Martins D; Smedley CJ; Li G; Forli S; Moses JE; Wolan DW; Sharpless KB
    Proc Natl Acad Sci U S A; 2019 Sep; 116(38):18808-18814. PubMed ID: 31484779
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inactivation of human neutrophil elastase by 1,2,5-thiadiazolidin-3-one 1,1 dioxide-based sulfonamides.
    Li Y; Yang Q; Dou D; Alliston KR; Groutas WC
    Bioorg Med Chem; 2008 Jan; 16(2):692-8. PubMed ID: 17976994
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and mechanism of action of novel thiocarbamate inhibitors of human leukocyte elastase.
    Li-Pan ZS; Joshi HV; Digenis GA
    J Enzyme Inhib; 2000; 15(1):63-77. PubMed ID: 10850955
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 1,5,6,7-Tetrahydro-4H-indazol-4-ones as human neutrophil elastase (HNE) inhibitors.
    Cantini N; Crocetti L; Guerrini G; Vergelli C; Schepetkin IA; Pallecchi M; Bartolucci G; Quinn MT; Teodori E; Giovannoni MP
    Bioorg Med Chem Lett; 2021 Nov; 52():128380. PubMed ID: 34563669
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanism-based inhibitors of serine proteases with high selectivity through optimization of S' subsite binding.
    Li Y; Dou D; He G; Lushington GH; Groutas WC
    Bioorg Med Chem; 2009 May; 17(10):3536-42. PubMed ID: 19394830
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphonic pseudopeptides as human neutrophil elastase inhibitors--a combinatorial approach.
    Sieńczyk M; Podgórski D; Błażejewska A; Kulbacka J; Saczko J; Oleksyszyn J
    Bioorg Med Chem; 2011 Feb; 19(3):1277-84. PubMed ID: 21216608
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Natural Phenolics as Inhibitors of the Human Neutrophil Elastase (HNE) Release: An Overview of Natural Anti-inflammatory Discoveries during Recent Years.
    Saleem M; Nazir M; Hussain H; Tousif MI; Elsebai MF; Riaz N; Akhtar N
    Antiinflamm Antiallergy Agents Med Chem; 2018; 17(2):70-94. PubMed ID: 30198444
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Proline-based macrocyclic inhibitors of the hepatitis C virus: stereoselective synthesis and biological activity.
    Chen KX; Njoroge FG; Vibulbhan B; Prongay A; Pichardo J; Madison V; Buevich A; Chan TM
    Angew Chem Int Ed Engl; 2005 Nov; 44(43):7024-8. PubMed ID: 16211639
    [No Abstract]   [Full Text] [Related]  

  • 17. Natural compounds as inhibitors of human neutrophil elastase.
    Siedle B; Hrenn A; Merfort I
    Planta Med; 2007 May; 73(5):401-20. PubMed ID: 17447201
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel locust (Schistocerca gregaria) serine protease inhibitor with a high affinity for neutrophil elastase.
    Brillard-Bourdet M; Hamdaoui A; Hajjar E; Boudier C; Reuter N; Ehret-Sabatier L; Bieth JG; Gauthier F
    Biochem J; 2006 Dec; 400(3):467-76. PubMed ID: 16839309
    [TBL] [Abstract][Full Text] [Related]  

  • 19. X-ray snapshot of the mechanism of inactivation of human neutrophil elastase by 1,2,5-thiadiazolidin-3-one 1,1-dioxide derivatives.
    Huang W; Yamamoto Y; Li Y; Dou D; Alliston KR; Hanzlik RP; Williams TD; Groutas WC
    J Med Chem; 2008 Apr; 51(7):2003-8. PubMed ID: 18318470
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Leucine-phenylalanine dipeptide-based N-mesyloxysuccinimides: synthesis of all four stereoisomers and their assay against serine proteases.
    Abell AD; Oldham MD
    Bioorg Med Chem Lett; 1999 Feb; 9(3):497-500. PubMed ID: 10091709
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.