BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

218 related articles for article (PubMed ID: 33022452)

  • 1. Mesenchyme-specific loss of Dot1L histone methyltransferase leads to skeletal dysplasia phenotype in mice.
    Sutter PA; Karki S; Crawley I; Singh V; Bernt KM; Rowe DW; Crocker SJ; Bayarsaihan D; Guzzo RM
    Bone; 2021 Jan; 142():115677. PubMed ID: 33022452
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeted disruption of the histone lysine 79 methyltransferase Dot1L in nephron progenitors causes congenital renal dysplasia.
    Wang F; Ngo J; Li Y; Liu H; Chen CH; Saifudeen Z; Sequeira-Lopez MLS; El-Dahr SS
    Epigenetics; 2021 Nov; 16(11):1235-1250. PubMed ID: 33315499
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Role of
    Jo SY; Domowicz MS; Henry JG; Schwartz NB
    JBMR Plus; 2020 Feb; 4(2):e10254. PubMed ID: 32083237
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Increased susceptibility to develop spontaneous and post-traumatic osteoarthritis in Dot1l-deficient mice.
    Cornelis FMF; de Roover A; Storms L; Hens A; Lories RJ; Monteagudo S
    Osteoarthritis Cartilage; 2019 Mar; 27(3):513-525. PubMed ID: 30513362
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Single-cell transcriptomics defines Dot1L interacting partners and downstream target genes in the mouse molar dental pulp.
    Guzzo R; Enkhmandakh B; Becker T; Joshi P; Robson P; Vijaykumar A; Mina M; Shin DG; Bayarsaihan D
    Int J Dev Biol; 2022; 66(7-8-9):391-400. PubMed ID: 36942693
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential Methylation of H3K79 Reveals DOT1L Target Genes and Function in the Cerebellum In Vivo.
    Bovio PP; Franz H; Heidrich S; Rauleac T; Kilpert F; Manke T; Vogel T
    Mol Neurobiol; 2019 Jun; 56(6):4273-4287. PubMed ID: 30302725
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ESET histone methyltransferase is essential to hypertrophic differentiation of growth plate chondrocytes and formation of epiphyseal plates.
    Yang L; Lawson KA; Teteak CJ; Zou J; Hacquebord J; Patterson D; Ghatan AC; Mei Q; Zielinska-Kwiatkowska A; Bain SD; Fernandes RJ; Chansky HA
    Dev Biol; 2013 Aug; 380(1):99-110. PubMed ID: 23652029
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer.
    Yang L; Lei Q; Li L; Yang J; Dong Z; Cui H
    Clin Epigenetics; 2019 Dec; 11(1):199. PubMed ID: 31888761
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor.
    FitzGerald J; Moureau S; Drogaris P; O'Connell E; Abshiru N; Verreault A; Thibault P; Grenon M; Lowndes NF
    PLoS One; 2011 Feb; 6(2):e14714. PubMed ID: 21383990
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differentiation and localization of interneurons in the developing spinal cord depends on DOT1L expression.
    Gray de Cristoforis A; Ferrari F; Clotman F; Vogel T
    Mol Brain; 2020 May; 13(1):85. PubMed ID: 32471461
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The disruptor of telomeric silencing 1-like (DOT1L) promotes peritoneal fibrosis through the upregulation and activation of protein tyrosine kinases.
    Tao M; Shi Y; Chen H; Li J; Wang Y; Ma X; Du L; Wang Y; Yang X; Hu Y; Zhou X; Zhong Q; Yan D; Qiu A; Zhuang S; Liu N
    Mol Biomed; 2024 Jan; 5(1):3. PubMed ID: 38172378
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Conditional Deletion of Indian Hedgehog in Limb Mesenchyme Results in Complete Loss of Growth Plate Formation but Allows Mature Osteoblast Differentiation.
    Amano K; Densmore MJ; Lanske B
    J Bone Miner Res; 2015 Dec; 30(12):2262-72. PubMed ID: 26094741
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting of histone methyltransferase DOT1L plays a dual role in chemosensitization of retinoblastoma cells and enhances the efficacy of chemotherapy.
    Mao Y; Sun Y; Wu Z; Zheng J; Zhang J; Zeng J; Lee C; Kim JK
    Cell Death Dis; 2021 Dec; 12(12):1141. PubMed ID: 34887387
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure.
    Jones B; Su H; Bhat A; Lei H; Bajko J; Hevi S; Baltus GA; Kadam S; Zhai H; Valdez R; Gonzalo S; Zhang Y; Li E; Chen T
    PLoS Genet; 2008 Sep; 4(9):e1000190. PubMed ID: 18787701
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Maternal DOT1L is dispensable for mouse development.
    Liao J; Szabó PE
    Sci Rep; 2020 Nov; 10(1):20636. PubMed ID: 33244015
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Histone Methyltransferase DOT1L Is Essential for Humoral Immune Responses.
    Kealy L; Di Pietro A; Hailes L; Scheer S; Dalit L; Groom JR; Zaph C; Good-Jacobson KL
    Cell Rep; 2020 Dec; 33(11):108504. PubMed ID: 33326791
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Histone methyltransferase Dot1L plays a role in postembryonic development in Xenopus tropicalis.
    Wen L; Fu L; Guo X; Chen Y; Shi YB
    FASEB J; 2015 Feb; 29(2):385-93. PubMed ID: 25366346
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.
    Jo SY; Granowicz EM; Maillard I; Thomas D; Hess JL
    Blood; 2011 May; 117(18):4759-68. PubMed ID: 21398221
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.
    Chen CW; Koche RP; Sinha AU; Deshpande AJ; Zhu N; Eng R; Doench JG; Xu H; Chu SH; Qi J; Wang X; Delaney C; Bernt KM; Root DE; Hahn WC; Bradner JE; Armstrong SA
    Nat Med; 2015 Apr; 21(4):335-43. PubMed ID: 25822366
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Prognostic and therapeutic value of disruptor of telomeric silencing-1-like (DOT1L) expression in patients with ovarian cancer.
    Zhang X; Liu D; Li M; Cao C; Wan D; Xi B; Li W; Tan J; Wang J; Wu Z; Ma D; Gao Q
    J Hematol Oncol; 2017 Jan; 10(1):29. PubMed ID: 28114995
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.