BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

284 related articles for article (PubMed ID: 33023230)

  • 1. The Roles of SPOP in DNA Damage Response and DNA Replication.
    Maekawa M; Higashiyama S
    Int J Mol Sci; 2020 Oct; 21(19):. PubMed ID: 33023230
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Destruction of DDIT3/CHOP protein by wild-type SPOP but not prostate cancer-associated mutants.
    Zhang P; Gao K; Tang Y; Jin X; An J; Yu H; Wang H; Zhang Y; Wang D; Huang H; Yu L; Wang C
    Hum Mutat; 2014 Sep; 35(9):1142-51. PubMed ID: 24990631
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Endometrial cancer-associated mutants of SPOP are defective in regulating estrogen receptor-α protein turnover.
    Zhang P; Gao K; Jin X; Ma J; Peng J; Wumaier R; Tang Y; Zhang Y; An J; Yan Q; Dong Y; Huang H; Yu L; Wang C
    Cell Death Dis; 2015 Mar; 6(3):e1687. PubMed ID: 25766326
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors.
    Janouskova H; El Tekle G; Bellini E; Udeshi ND; Rinaldi A; Ulbricht A; Bernasocchi T; Civenni G; Losa M; Svinkina T; Bielski CM; Kryukov GV; Cascione L; Napoli S; Enchev RI; Mutch DG; Carney ME; Berchuck A; Winterhoff BJN; Broaddus RR; Schraml P; Moch H; Bertoni F; Catapano CV; Peter M; Carr SA; Garraway LA; Wild PJ; Theurillat JP
    Nat Med; 2017 Sep; 23(9):1046-1054. PubMed ID: 28805821
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The emerging role of speckle-type POZ protein (SPOP) in cancer development.
    Mani RS
    Drug Discov Today; 2014 Sep; 19(9):1498-502. PubMed ID: 25058385
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SPOP is essential for DNA replication licensing through maintaining translation of CDT1 and CDC6 in HaCaT cells.
    Sanada S; Maekawa M; Tate S; Nakaoka H; Fujisawa Y; Sayama K; Higashiyama S
    Biochem Biophys Res Commun; 2023 Apr; 651():30-38. PubMed ID: 36791496
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SPOP is essential for DNA-protein cross-link repair in prostate cancer cells: SPOP-dependent removal of topoisomerase 2A from the topoisomerase 2A-DNA cleavage complex.
    Watanabe R; Maekawa M; Hieda M; Taguchi T; Miura N; Kikugawa T; Saika T; Higashiyama S
    Mol Biol Cell; 2020 Mar; 31(6):478-490. PubMed ID: 31967940
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover.
    Geng C; He B; Xu L; Barbieri CE; Eedunuri VK; Chew SA; Zimmermann M; Bond R; Shou J; Li C; Blattner M; Lonard DM; Demichelis F; Coarfa C; Rubin MA; Zhou P; O'Malley BW; Mitsiades N
    Proc Natl Acad Sci U S A; 2013 Apr; 110(17):6997-7002. PubMed ID: 23559371
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability.
    Hjorth-Jensen K; Maya-Mendoza A; Dalgaard N; Sigurðsson JO; Bartek J; Iglesias-Gato D; Olsen JV; Flores-Morales A
    Nucleic Acids Res; 2018 Oct; 46(18):9484-9495. PubMed ID: 30124983
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation.
    Wu F; Dai X; Gan W; Wan L; Li M; Mitsiades N; Wei W; Ding Q; Zhang J
    Cancer Lett; 2017 Jan; 385():207-214. PubMed ID: 27780719
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Coordinated activation of the nuclear ubiquitin ligase Cul3-SPOP by the generation of phosphatidylinositol 5-phosphate.
    Bunce MW; Boronenkov IV; Anderson RA
    J Biol Chem; 2008 Mar; 283(13):8678-86. PubMed ID: 18218622
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural basis of high-order oligomerization of the cullin-3 adaptor SPOP.
    van Geersdaele LK; Stead MA; Harrison CM; Carr SB; Close HJ; Rosbrook GO; Connell SD; Wright SC
    Acta Crystallogr D Biol Crystallogr; 2013 Sep; 69(Pt 9):1677-84. PubMed ID: 23999291
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CHD1 and SPOP synergistically protect prostate epithelial cells from DNA damage.
    Zhu Y; Wen J; Huang G; Mittlesteadt J; Wen X; Lu X
    Prostate; 2021 Jan; 81(1):81-88. PubMed ID: 33022763
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Deregulation of SPOP in Cancer.
    Zhang H; Jin X; Huang H
    Cancer Res; 2023 Feb; 83(4):489-499. PubMed ID: 36512624
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dysregulation of INF2-mediated mitochondrial fission in SPOP-mutated prostate cancer.
    Jin X; Wang J; Gao K; Zhang P; Yao L; Tang Y; Tang L; Ma J; Xiao J; Zhang E; Zhu J; Zhang B; Zhao SM; Li Y; Ren S; Huang H; Yu L; Wang C
    PLoS Genet; 2017 Apr; 13(4):e1006748. PubMed ID: 28448495
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
    Zhuang M; Calabrese MF; Liu J; Waddell MB; Nourse A; Hammel M; Miller DJ; Walden H; Duda DM; Seyedin SN; Hoggard T; Harper JW; White KP; Schulman BA
    Mol Cell; 2009 Oct; 36(1):39-50. PubMed ID: 19818708
    [TBL] [Abstract][Full Text] [Related]  

  • 17. G3BP1 inhibits Cul3
    Mukhopadhyay C; Yang C; Xu L; Liu D; Wang Y; Huang D; Deonarine LD; Cyrta J; Davicioni E; Sboner A; Robinson BD; Chinnaiyan AM; Rubin MA; Barbieri CE; Zhou P
    Nat Commun; 2021 Nov; 12(1):6662. PubMed ID: 34795264
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prostate cancer-associated SPOP mutations lead to genomic instability through disruption of the SPOP-HIPK2 axis.
    Jin X; Qing S; Li Q; Zhuang H; Shen L; Li J; Qi H; Lin T; Lin Z; Wang J; Cao X; Yang J; Ma Q; Cong L; Xi Y; Fang S; Meng X; Gong Z; Ye M; Wang S; Wang C; Gao K
    Nucleic Acids Res; 2021 Jul; 49(12):6788-6803. PubMed ID: 34133717
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SPOP in Cancer: Phenomena, Mechanisms and Its Role in Therapeutic Implications.
    Yang X; Zhu Q
    Genes (Basel); 2022 Nov; 13(11):. PubMed ID: 36360288
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SPOP promotes ATF2 ubiquitination and degradation to suppress prostate cancer progression.
    Ma J; Chang K; Peng J; Shi Q; Gan H; Gao K; Feng K; Xu F; Zhang H; Dai B; Zhu Y; Shi G; Shen Y; Zhu Y; Qin X; Li Y; Zhang P; Ye D; Wang C
    J Exp Clin Cancer Res; 2018 Jul; 37(1):145. PubMed ID: 29996942
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.