BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 33035641)

  • 21. Targeting RAS oncogenesis with SOS1 inhibitors.
    Hillig RC; Bader B
    Adv Cancer Res; 2022; 153():169-203. PubMed ID: 35101230
    [TBL] [Abstract][Full Text] [Related]  

  • 22. CIIA functions as a molecular switch for the Rac1-specific GEF activity of SOS1.
    Hwang HS; Hwang SG; Cho JH; Chae JS; Yoon KW; Cho SG; Choi EJ
    J Cell Biol; 2011 Oct; 195(3):377-86. PubMed ID: 22042618
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Activating Mutations Affecting the Dbl Homology Domain of SOS2 Cause Noonan Syndrome.
    Cordeddu V; Yin JC; Gunnarsson C; Virtanen C; Drunat S; Lepri F; De Luca A; Rossi C; Ciolfi A; Pugh TJ; Bruselles A; Priest JR; Pennacchio LA; Lu Z; Danesh A; Quevedo R; Hamid A; Martinelli S; Pantaleoni F; Gnazzo M; Daniele P; Lissewski C; Bocchinfuso G; Stella L; Odent S; Philip N; Faivre L; Vlckova M; Seemanova E; Digilio C; Zenker M; Zampino G; Verloes A; Dallapiccola B; Roberts AE; Cavé H; Gelb BD; Neel BG; Tartaglia M
    Hum Mutat; 2015 Nov; 36(11):1080-7. PubMed ID: 26173643
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Activation of Ras-dependent signaling pathways by G(14) -coupled receptors requires the adaptor protein TPR1.
    Kwan DH; Yung LY; Ye RD; Wong YH
    J Cell Biochem; 2012 Nov; 113(11):3486-97. PubMed ID: 22711498
    [TBL] [Abstract][Full Text] [Related]  

  • 25. An orthosteric inhibitor of the RAS-SOS interaction.
    Nickerson S; Joy ST; Arora PS; Bar-Sagi D
    Enzymes; 2013; 34 Pt. B():25-39. PubMed ID: 25034099
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Mammalian son of sevenless Guanine nucleotide exchange factors: old concepts and new perspectives.
    Rojas JM; Oliva JL; Santos E
    Genes Cancer; 2011 Mar; 2(3):298-305. PubMed ID: 21779500
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Inhibitors of Ras-SOS Interactions.
    Lu S; Jang H; Zhang J; Nussinov R
    ChemMedChem; 2016 Apr; 11(8):814-21. PubMed ID: 26630662
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Sos1 regulates sustained TCR-mediated Erk activation.
    Poltorak M; Meinert I; Stone JC; Schraven B; Simeoni L
    Eur J Immunol; 2014 May; 44(5):1535-40. PubMed ID: 24497027
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.
    Nimnual AS; Yatsula BA; Bar-Sagi D
    Science; 1998 Jan; 279(5350):560-3. PubMed ID: 9438849
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Guanine nucleotide exchange factors: activators of Ras superfamily proteins.
    Overbeck AF; Brtva TR; Cox AD; Graham SM; Huff SY; Khosravi-Far R; Quilliam LA; Solski PA; Der CJ
    Mol Reprod Dev; 1995 Dec; 42(4):468-76. PubMed ID: 8607978
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Small Molecule-Mediated Activation of RAS Elicits Biphasic Modulation of Phospho-ERK Levels that Are Regulated through Negative Feedback on SOS1.
    Howes JE; Akan DT; Burns MC; Rossanese OW; Waterson AG; Fesik SW
    Mol Cancer Ther; 2018 May; 17(5):1051-1060. PubMed ID: 29440291
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Ras-guanine nucleotide exchange factor sos2 is dispensable for mouse growth and development.
    Esteban LM; Fernández-Medarde A; López E; Yienger K; Guerrero C; Ward JM; Tessarollo L; Santos E
    Mol Cell Biol; 2000 Sep; 20(17):6410-3. PubMed ID: 10938118
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase C-gamma2 to Ras in B cell receptor signaling.
    Oh-hora M; Johmura S; Hashimoto A; Hikida M; Kurosaki T
    J Exp Med; 2003 Dec; 198(12):1841-51. PubMed ID: 14676298
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Regulation of ras signaling dynamics by Sos-mediated positive feedback.
    Boykevisch S; Zhao C; Sondermann H; Philippidou P; Halegoua S; Kuriyan J; Bar-Sagi D
    Curr Biol; 2006 Nov; 16(21):2173-9. PubMed ID: 17084704
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Rare variants in SOS2 and LZTR1 are associated with Noonan syndrome.
    Yamamoto GL; Aguena M; Gos M; Hung C; Pilch J; Fahiminiya S; Abramowicz A; Cristian I; Buscarilli M; Naslavsky MS; Malaquias AC; Zatz M; Bodamer O; Majewski J; Jorge AA; Pereira AC; Kim CA; Passos-Bueno MR; Bertola DR
    J Med Genet; 2015 Jun; 52(6):413-21. PubMed ID: 25795793
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Galpha16 activates Ras by forming a complex with tetratricopeptide repeat 1 (TPR1) and Son of Sevenless (SOS).
    Liu AM; Lo RK; Lee MM; Wang Y; Yeung WW; Ho MK; Su Y; Ye RD; Wong YH
    Cell Signal; 2010 Oct; 22(10):1448-58. PubMed ID: 20639119
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Membrane-dependent signal integration by the Ras activator Son of sevenless.
    Gureasko J; Galush WJ; Boykevisch S; Sondermann H; Bar-Sagi D; Groves JT; Kuriyan J
    Nat Struct Mol Biol; 2008 May; 15(5):452-61. PubMed ID: 18454158
    [TBL] [Abstract][Full Text] [Related]  

  • 38. An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machine.
    Scita G; Tenca P; Areces LB; Tocchetti A; Frittoli E; Giardina G; Ponzanelli I; Sini P; Innocenti M; Di Fiore PP
    J Cell Biol; 2001 Sep; 154(5):1031-44. PubMed ID: 11524436
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Molecular origin and functional consequences of digital signaling and hysteresis during Ras activation in lymphocytes.
    Chakraborty AK; Das J; Zikherman J; Yang M; Govern CC; Ho M; Weiss A; Roose J
    Sci Signal; 2009 Apr; 2(66):pt2. PubMed ID: 19366993
    [TBL] [Abstract][Full Text] [Related]  

  • 40. An activating mutation in sos-1 identifies its Dbl domain as a critical inhibitor of the epidermal growth factor receptor pathway during Caenorhabditis elegans vulval development.
    Modzelewska K; Elgort MG; Huang J; Jongeward G; Lauritzen A; Yoon CH; Sternberg PW; Moghal N
    Mol Cell Biol; 2007 May; 27(10):3695-707. PubMed ID: 17339331
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.