170 related articles for article (PubMed ID: 33035646)
1. Structure-function analysis of lipid substrates and inhibitors of sphingosine kinases.
Adams DR; Pyne S; Pyne NJ
Cell Signal; 2020 Dec; 76():109806. PubMed ID: 33035646
[TBL] [Abstract][Full Text] [Related]
2. Dimethylsphingosine and FTY720 inhibit the SK1 form but activate the SK2 form of sphingosine kinase from rat heart.
Vessey DA; Kelley M; Zhang J; Li L; Tao R; Karliner JS
J Biochem Mol Toxicol; 2007; 21(5):273-9. PubMed ID: 17912702
[TBL] [Abstract][Full Text] [Related]
3. FTY720 analogues as sphingosine kinase 1 inhibitors: enzyme inhibition kinetics, allosterism, proteasomal degradation, and actin rearrangement in MCF-7 breast cancer cells.
Lim KG; Tonelli F; Li Z; Lu X; Bittman R; Pyne S; Pyne NJ
J Biol Chem; 2011 May; 286(21):18633-40. PubMed ID: 21464128
[TBL] [Abstract][Full Text] [Related]
4. (R)-FTY720 methyl ether is a specific sphingosine kinase 2 inhibitor: Effect on sphingosine kinase 2 expression in HEK 293 cells and actin rearrangement and survival of MCF-7 breast cancer cells.
Lim KG; Sun C; Bittman R; Pyne NJ; Pyne S
Cell Signal; 2011 Oct; 23(10):1590-5. PubMed ID: 21620961
[TBL] [Abstract][Full Text] [Related]
5. Short Periods of Hypoxia Upregulate Sphingosine Kinase 1 and Increase Vasodilation of Arteries to Sphingosine 1-Phosphate (S1P) via S1P
Alganga H; Almabrouk TAM; Katwan OJ; Daly CJ; Pyne S; Pyne NJ; Kennedy S
J Pharmacol Exp Ther; 2019 Oct; 371(1):63-74. PubMed ID: 31371480
[TBL] [Abstract][Full Text] [Related]
6. FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells.
Tonelli F; Lim KG; Loveridge C; Long J; Pitson SM; Tigyi G; Bittman R; Pyne S; Pyne NJ
Cell Signal; 2010 Oct; 22(10):1536-42. PubMed ID: 20570726
[TBL] [Abstract][Full Text] [Related]
7. The roles of sphingosine kinases 1 and 2 in regulating the Warburg effect in prostate cancer cells.
Watson DG; Tonelli F; Alossaimi M; Williamson L; Chan E; Gorshkova I; Berdyshev E; Bittman R; Pyne NJ; Pyne S
Cell Signal; 2013 Apr; 25(4):1011-7. PubMed ID: 23314175
[TBL] [Abstract][Full Text] [Related]
8. Topographical Mapping of Isoform-Selectivity Determinants for J-Channel-Binding Inhibitors of Sphingosine Kinases 1 and 2.
Adams DR; Tawati S; Berretta G; Rivas PL; Baiget J; Jiang Z; Alsfouk A; Mackay SP; Pyne NJ; Pyne S
J Med Chem; 2019 Apr; 62(7):3658-3676. PubMed ID: 30889352
[TBL] [Abstract][Full Text] [Related]
9. Characterization of isoenzyme-selective inhibitors of human sphingosine kinases.
Gao P; Peterson YK; Smith RA; Smith CD
PLoS One; 2012; 7(9):e44543. PubMed ID: 22970244
[TBL] [Abstract][Full Text] [Related]
10. Subcellular distribution of FTY720 and FTY720-phosphate in immune cells - another aspect of Fingolimod action relevant for therapeutic application.
Schröder M; Arlt O; Schmidt H; Huwiler A; Angioni C; Pfeilschifter JM; Schwiebs A; Radeke HH
Biol Chem; 2015 Jun; 396(6-7):795-802. PubMed ID: 25720062
[TBL] [Abstract][Full Text] [Related]
11. Assessment of the effect of sphingosine kinase inhibitors on apoptosis,unfolded protein response and autophagy of T-cell acute lymphoblastic leukemia cells; indications for novel therapeutics.
Evangelisti C; Evangelisti C; Teti G; Chiarini F; Falconi M; Melchionda F; Pession A; Bertaina A; Locatelli F; McCubrey JA; Beak DJ; Bittman R; Pyne S; Pyne NJ; Martelli AM
Oncotarget; 2014 Sep; 5(17):7886-901. PubMed ID: 25226616
[TBL] [Abstract][Full Text] [Related]
12. Sphingosine kinase 1 in cancer.
Heffernan-Stroud LA; Obeid LM
Adv Cancer Res; 2013; 117():201-35. PubMed ID: 23290781
[TBL] [Abstract][Full Text] [Related]
13. Sphingosine 1-phosphate and sphingosine kinases in health and disease: Recent advances.
Pyne S; Adams DR; Pyne NJ
Prog Lipid Res; 2016 Apr; 62():93-106. PubMed ID: 26970273
[TBL] [Abstract][Full Text] [Related]
14. Fingolimod targeting protein phosphatase 2A differently affects IL-33 induced IL-2 and IFN-γ production in CD8(+) lymphocytes.
Ottenlinger F; Schwiebs A; Pfarr K; Wagner A; Grüner S; Mayer CA; Pfeilschifter JM; Radeke HH
Eur J Immunol; 2016 Apr; 46(4):941-51. PubMed ID: 26683421
[TBL] [Abstract][Full Text] [Related]
15. Role of sphingosine 1-phosphate receptors, sphingosine kinases and sphingosine in cancer and inflammation.
Pyne NJ; McNaughton M; Boomkamp S; MacRitchie N; Evangelisti C; Martelli AM; Jiang HR; Ubhi S; Pyne S
Adv Biol Regul; 2016 Jan; 60():151-159. PubMed ID: 26429117
[TBL] [Abstract][Full Text] [Related]
16. The sphingosine kinase inhibitor 2-(p-hyroxyanilino)-4-(p-chlorophenyl)thiazole reduces androgen receptor expression via an oxidative stress-dependent mechanism.
Tonelli F; Alossaimi M; Williamson L; Tate RJ; Watson DG; Chan E; Bittman R; Pyne NJ; Pyne S
Br J Pharmacol; 2013 Mar; 168(6):1497-505. PubMed ID: 23113536
[TBL] [Abstract][Full Text] [Related]
17. Effects of phosphorylation of immunomodulatory agent FTY720 (fingolimod) on antiproliferative activity against breast and colon cancer cells.
Nagaoka Y; Otsuki K; Fujita T; Uesato S
Biol Pharm Bull; 2008 Jun; 31(6):1177-81. PubMed ID: 18520051
[TBL] [Abstract][Full Text] [Related]
18. Functional characterization of sphingosine 1-phosphate receptor agonist in human endothelial cells.
Butler J; Lana D; Round O; LaMontagne K
Prostaglandins Other Lipid Mediat; 2004 Jan; 73(1-2):29-45. PubMed ID: 15165029
[TBL] [Abstract][Full Text] [Related]
19. Effect of alkyl chain length on sphingosine kinase 2 selectivity.
Knott K; Kharel Y; Raje MR; Lynch KR; Santos WL
Bioorg Med Chem Lett; 2012 Nov; 22(22):6817-20. PubMed ID: 22321213
[TBL] [Abstract][Full Text] [Related]
20. Prominence of central sphingosine-1-phosphate receptor-1 in attenuating aβ-induced injury by fingolimod.
Asle-Rousta M; Kolahdooz Z; Dargahi L; Ahmadiani A; Nasoohi S
J Mol Neurosci; 2014 Dec; 54(4):698-703. PubMed ID: 25239520
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]