These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Reversal of diet-induced hepatic steatosis by peripheral CB1 receptor blockade in mice is p53/miRNA-22/SIRT1/PPARα dependent. Azar S; Udi S; Drori A; Hadar R; Nemirovski A; Vemuri KV; Miller M; Sherill-Rofe D; Arad Y; Gur-Wahnon D; Li X; Makriyannis A; Ben-Zvi D; Tabach Y; Ben-Dov IZ; Tam J Mol Metab; 2020 Dec; 42():101087. PubMed ID: 32987186 [TBL] [Abstract][Full Text] [Related]
4. SIRT4 represses peroxisome proliferator-activated receptor α activity to suppress hepatic fat oxidation. Laurent G; de Boer VC; Finley LW; Sweeney M; Lu H; Schug TT; Cen Y; Jeong SM; Li X; Sauve AA; Haigis MC Mol Cell Biol; 2013 Nov; 33(22):4552-61. PubMed ID: 24043310 [TBL] [Abstract][Full Text] [Related]
5. Lycopene and apo-10'-lycopenoic acid have differential mechanisms of protection against hepatic steatosis in β-carotene-9',10'-oxygenase knockout male mice. Ip BC; Liu C; Lichtenstein AH; von Lintig J; Wang XD J Nutr; 2015 Feb; 145(2):268-76. PubMed ID: 25644347 [TBL] [Abstract][Full Text] [Related]
6. The PPARβ/δ activator GW501516 prevents the down-regulation of AMPK caused by a high-fat diet in liver and amplifies the PGC-1α-Lipin 1-PPARα pathway leading to increased fatty acid oxidation. Barroso E; Rodríguez-Calvo R; Serrano-Marco L; Astudillo AM; Balsinde J; Palomer X; Vázquez-Carrera M Endocrinology; 2011 May; 152(5):1848-59. PubMed ID: 21363937 [TBL] [Abstract][Full Text] [Related]
7. Fasting-induced JMJD3 histone demethylase epigenetically activates mitochondrial fatty acid β-oxidation. Seok S; Kim YC; Byun S; Choi S; Xiao Z; Iwamori N; Zhang Y; Wang C; Ma J; Ge K; Kemper B; Kemper JK J Clin Invest; 2018 Jul; 128(7):3144-3159. PubMed ID: 29911994 [TBL] [Abstract][Full Text] [Related]
8. The diabetes medication canagliflozin promotes mitochondrial remodelling of adipocyte via the AMPK-Sirt1-Pgc-1α signalling pathway. Yang X; Liu Q; Li Y; Tang Q; Wu T; Chen L; Pu S; Zhao Y; Zhang G; Huang C; Zhang J; Zhang Z; Huang Y; Zou M; Shi X; Jiang W; Wang R; He J Adipocyte; 2020 Dec; 9(1):484-494. PubMed ID: 32835596 [TBL] [Abstract][Full Text] [Related]
9. Hypoxia via ERK Signaling Inhibits Hepatic PPARα to Promote Fatty Liver. Mooli RGR; Rodriguez J; Takahashi S; Solanki S; Gonzalez FJ; Ramakrishnan SK; Shah YM Cell Mol Gastroenterol Hepatol; 2021; 12(2):585-597. PubMed ID: 33798787 [TBL] [Abstract][Full Text] [Related]
10. Sodium butyrate alleviates free fatty acid-induced steatosis in primary chicken hepatocytes via the AMPK/PPARα pathway. Ding J; Liu J; Chen J; Cheng X; Cao H; Guo X; Hu G; Zhuang Y Poult Sci; 2024 Apr; 103(4):103482. PubMed ID: 38387286 [TBL] [Abstract][Full Text] [Related]
11. Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation. Purushotham A; Schug TT; Xu Q; Surapureddi S; Guo X; Li X Cell Metab; 2009 Apr; 9(4):327-38. PubMed ID: 19356714 [TBL] [Abstract][Full Text] [Related]
12. A conjugated fatty acid present at high levels in bitter melon seed favorably affects lipid metabolism in hepatocytes by increasing NAD(+)/NADH ratio and activating PPARα, AMPK and SIRT1 signaling pathway. Chen GC; Su HM; Lin YS; Tsou PY; Chyuan JH; Chao PM J Nutr Biochem; 2016 Jul; 33():28-35. PubMed ID: 27260465 [TBL] [Abstract][Full Text] [Related]
13. SIRT1 performs a balancing act on the tight-rope toward longevity. Purushotham A; Schug TT; Li X Aging (Albany NY); 2009 Jul; 1(7):669-73. PubMed ID: 20157548 [TBL] [Abstract][Full Text] [Related]
14. Nordihydroguaiaretic acid improves metabolic dysregulation and aberrant hepatic lipid metabolism in mice by both PPARα-dependent and -independent pathways. Zhang H; Shen WJ; Cortez Y; Kraemer FB; Azhar S Am J Physiol Gastrointest Liver Physiol; 2013 Jan; 304(1):G72-86. PubMed ID: 23104557 [TBL] [Abstract][Full Text] [Related]
15. Hepatocyte Peroxisome Proliferator-Activated Receptor α Enhances Liver Regeneration after Partial Hepatectomy in Mice. Xie G; Yin S; Zhang Z; Qi D; Wang X; Kim D; Yagai T; Brocker CN; Wang Y; Gonzalez FJ; Wang H; Qu A Am J Pathol; 2019 Feb; 189(2):272-282. PubMed ID: 30448405 [TBL] [Abstract][Full Text] [Related]
16. Fisetin Protects Against Hepatic Steatosis Through Regulation of the Sirt1/AMPK and Fatty Acid β-Oxidation Signaling Pathway in High-Fat Diet-Induced Obese Mice. Liou CJ; Wei CH; Chen YL; Cheng CY; Wang CL; Huang WC Cell Physiol Biochem; 2018; 49(5):1870-1884. PubMed ID: 30235452 [TBL] [Abstract][Full Text] [Related]
17. Gα12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration. Kim TH; Yang YM; Han CY; Koo JH; Oh H; Kim SS; You BH; Choi YH; Park TS; Lee CH; Kurose H; Noureddin M; Seki E; Wan YY; Choi CS; Kim SG J Clin Invest; 2018 Dec; 128(12):5587-5602. PubMed ID: 30300140 [TBL] [Abstract][Full Text] [Related]