BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

229 related articles for article (PubMed ID: 33038548)

  • 1. hDM2 protein-binding peptides screened from stapled α-helical peptide phage display libraries with different types of staple linkers.
    Anananuchatkul T; Tsutsumi H; Miki T; Mihara H
    Bioorg Med Chem Lett; 2020 Dec; 30(23):127605. PubMed ID: 33038548
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Suprastapled Peptides: Hybridization-Enhanced Peptide Ligation and Enforced α-Helical Conformation for Affinity Selection of Combinatorial Libraries.
    Sabale PM; Imiołek M; Raia P; Barluenga S; Winssinger N
    J Am Chem Soc; 2021 Nov; 143(45):18932-18940. PubMed ID: 34739233
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effect of linker on the binding free energy of stapled p53/HDM2 complex.
    Im H; Ham S
    PLoS One; 2020; 15(4):e0232613. PubMed ID: 32353067
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Construction of a Stapled α-Helix Peptide Library Displayed on Phage for the Screening of Galectin-3-Binding Peptide Ligands.
    Anananuchatkul T; Chang IV; Miki T; Tsutsumi H; Mihara H
    ACS Omega; 2020 Mar; 5(11):5666-5674. PubMed ID: 32226843
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Thermodynamic and computational studies on the binding of p53-derived peptides and peptidomimetic inhibitors to HDM2.
    Grässlin A; Amoreira C; Baldridge KK; Robinson JA
    Chembiochem; 2009 May; 10(8):1360-8. PubMed ID: 19408261
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular characterization of the hdm2-p53 interaction.
    Böttger A; Böttger V; Garcia-Echeverria C; Chène P; Hochkeppel HK; Sampson W; Ang K; Howard SF; Picksley SM; Lane DP
    J Mol Biol; 1997 Jun; 269(5):744-56. PubMed ID: 9223638
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Stapled α-helical peptide drug development: a potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy.
    Chang YS; Graves B; Guerlavais V; Tovar C; Packman K; To KH; Olson KA; Kesavan K; Gangurde P; Mukherjee A; Baker T; Darlak K; Elkin C; Filipovic Z; Qureshi FZ; Cai H; Berry P; Feyfant E; Shi XE; Horstick J; Annis DA; Manning AM; Fotouhi N; Nash H; Vassilev LT; Sawyer TK
    Proc Natl Acad Sci U S A; 2013 Sep; 110(36):E3445-54. PubMed ID: 23946421
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of novel mdm2 binding peptides by phage display.
    Böttger V; Böttger A; Howard SF; Picksley SM; Chène P; Garcia-Echeverria C; Hochkeppel HK; Lane DP
    Oncogene; 1996 Nov; 13(10):2141-7. PubMed ID: 8950981
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Peptide-based inhibitors of protein-protein interactions.
    Wójcik P; Berlicki Ł
    Bioorg Med Chem Lett; 2016 Feb; 26(3):707-713. PubMed ID: 26764190
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A Cyclized Helix-Loop-Helix Peptide as a Molecular Scaffold for the Design of Inhibitors of Intracellular Protein-Protein Interactions by Epitope and Arginine Grafting.
    Fujiwara D; Kitada H; Oguri M; Nishihara T; Michigami M; Shiraishi K; Yuba E; Nakase I; Im H; Cho S; Joung JY; Kodama S; Kono K; Ham S; Fujii I
    Angew Chem Int Ed Engl; 2016 Aug; 55(36):10612-5. PubMed ID: 27467415
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure of a stapled peptide antagonist bound to nutlin-resistant Mdm2.
    Chee SM; Wongsantichon J; Soo Tng Q; Robinson R; Joseph TL; Verma C; Lane DP; Brown CJ; Ghadessy FJ
    PLoS One; 2014; 9(8):e104914. PubMed ID: 25115702
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Isolation of a peptide containing d-amino acid residues that inhibits the α-helix-mediated p53-MDM2 interaction from a one-bead one-compound library.
    Morimoto J; Hosono Y; Sando S
    Bioorg Med Chem Lett; 2018 Feb; 28(3):231-234. PubMed ID: 29326019
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Designing dual inhibitors of Mdm2/MdmX: Unexpected coupling of water with gatekeeper Y100/99.
    Lee XA; Verma C; Sim AYL
    Proteins; 2017 Aug; 85(8):1493-1506. PubMed ID: 28425639
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A critical assessment of the synthesis and biological activity of p53/human double minute 2-stapled peptide inhibitors.
    Wallbrecher R; Chène P; Ruetz S; Stachyra T; Vorherr T; Brock R
    Br J Pharmacol; 2017 Aug; 174(16):2613-2622. PubMed ID: 28436014
    [TBL] [Abstract][Full Text] [Related]  

  • 15. mRNA display selection of an optimized MDM2-binding peptide that potently inhibits MDM2-p53 interaction.
    Shiheido H; Takashima H; Doi N; Yanagawa H
    PLoS One; 2011 Mar; 6(3):e17898. PubMed ID: 21423613
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A facile method to screen inhibitors of protein-protein interactions including MDM2-p53 displayed on T7 phage.
    Ishi K; Sugawara F
    Biochem Pharmacol; 2008 May; 75(9):1743-50. PubMed ID: 18384755
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Avoiding drug resistance through extended drug target interfaces: a case for stapled peptides.
    Wei SJ; Chee S; Yurlova L; Lane D; Verma C; Brown C; Ghadessy F
    Oncotarget; 2016 May; 7(22):32232-46. PubMed ID: 27057630
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Miniature protein inhibitors of the p53-hDM2 interaction.
    Kritzer JA; Zutshi R; Cheah M; Ran FA; Webman R; Wongjirad TM; Schepartz A
    Chembiochem; 2006 Jan; 7(1):29-31. PubMed ID: 16397877
    [No Abstract]   [Full Text] [Related]  

  • 19. Expansion of protein interaction maps by phage peptide display using MDM2 as a prototypical conformationally flexible target protein.
    Burch L; Shimizu H; Smith A; Patterson C; Hupp TR
    J Mol Biol; 2004 Mar; 337(1):129-45. PubMed ID: 15001357
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanistic validation of a clinical lead stapled peptide that reactivates p53 by dual HDM2 and HDMX targeting.
    Wachter F; Morgan AM; Godes M; Mourtada R; Bird GH; Walensky LD
    Oncogene; 2017 Apr; 36(15):2184-2190. PubMed ID: 27721413
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.