BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 33039146)

  • 1. Cyclin Y binds and activates CDK4 to promote the G1/S phase transition in hepatocellular carcinoma cells via Rb signaling.
    Chen L; Wang X; Cheng H; Zhang W; Liu Y; Zeng W; Yu L; Huang C; Liu G
    Biochem Biophys Res Commun; 2020 Dec; 533(4):1162-1169. PubMed ID: 33039146
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Predictors of ribociclib-mediated antitumour effects in native and sorafenib-resistant human hepatocellular carcinoma cells.
    Reiter FP; Denk G; Ziesch A; Ofner A; Wimmer R; Hohenester S; Schiergens TS; Spampatti M; Ye L; Itzel T; Munker S; Teufel A; Gerbes AL; Mayerle J; De Toni EN
    Cell Oncol (Dordr); 2019 Oct; 42(5):705-715. PubMed ID: 31250364
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PRMT5 competitively binds to CDK4 to promote G1-S transition upon glucose induction in hepatocellular carcinoma.
    Yang H; Zhao X; Zhao L; Liu L; Li J; Jia W; Liu J; Huang G
    Oncotarget; 2016 Nov; 7(44):72131-72147. PubMed ID: 27708221
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CDK4/6 initiates Rb inactivation and CDK2 activity coordinates cell-cycle commitment and G1/S transition.
    Kim S; Leong A; Kim M; Yang HW
    Sci Rep; 2022 Oct; 12(1):16810. PubMed ID: 36207346
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cyclins and cyclin-dependent kinases: comparative study of hepatocellular carcinoma versus cirrhosis.
    Masaki T; Shiratori Y; Rengifo W; Igarashi K; Yamagata M; Kurokohchi K; Uchida N; Miyauchi Y; Yoshiji H; Watanabe S; Omata M; Kuriyama S
    Hepatology; 2003 Mar; 37(3):534-43. PubMed ID: 12601350
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Expression of cyclin E renders cyclin D-CDK4 dispensable for inactivation of the retinoblastoma tumor suppressor protein, activation of E2F, and G1-S phase progression.
    Keenan SM; Lents NH; Baldassare JJ
    J Biol Chem; 2004 Feb; 279(7):5387-96. PubMed ID: 14645251
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction point.
    Bisteau X; Paternot S; Colleoni B; Ecker K; Coulonval K; De Groote P; Declercq W; Hengst L; Roger PP
    PLoS Genet; 2013 May; 9(5):e1003546. PubMed ID: 23737759
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proliferative suppression by CDK4/6 inhibition: complex function of the retinoblastoma pathway in liver tissue and hepatoma cells.
    Rivadeneira DB; Mayhew CN; Thangavel C; Sotillo E; Reed CA; Graña X; Knudsen ES
    Gastroenterology; 2010 May; 138(5):1920-30. PubMed ID: 20100483
    [TBL] [Abstract][Full Text] [Related]  

  • 9. S-Phase entry upon ectopic expression of G1 cyclin-dependent kinases in the absence of retinoblastoma protein phosphorylation.
    Leng X; Connell-Crowley L; Goodrich D; Harper JW
    Curr Biol; 1997 Sep; 7(9):709-12. PubMed ID: 9285720
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel anticancer agent, SKLB70359, inhibits human hepatic carcinoma cells proliferation via G0/G1 cell cycle arrest and apoptosis induction.
    Dai XY; Zeng XX; Peng F; Han YY; Lin HJ; Xu YZ; Zhou T; Xie G; Deng Y; Mao YQ; Yu LT; Yang L; Zhao YL
    Cell Physiol Biochem; 2012; 29(1-2):281-90. PubMed ID: 22415097
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Cdk4/6-dependent phosphorylation gradient regulates the early to late G1 phase transition.
    Kaulich M; Link VM; Lapek JD; Lee YJ; Glass CK; Gonzalez DJ; Dowdy SF
    Sci Rep; 2021 Jul; 11(1):14736. PubMed ID: 34282211
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular mechanism underlying the functional loss of cyclindependent kinase inhibitors p16 and p27 in hepatocellular carcinoma.
    Matsuda Y
    World J Gastroenterol; 2008 Mar; 14(11):1734-40. PubMed ID: 18350604
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bisphenol S promotes the cell cycle progression and cell proliferation through ERα-cyclin D-CDK4/6-pRb pathway in MCF-7 breast cancer cells.
    Lin Z; Zhang X; Zhao F; Ru S
    Toxicol Appl Pharmacol; 2019 Mar; 366():75-82. PubMed ID: 30684532
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CADM1 regulates the G1/S transition and represses tumorigenicity through the Rb-E2F pathway in hepatocellular carcinoma.
    Zhang W; Xie HY; Ding SM; Xing CY; Chen A; Lai MC; Zhou L; Zheng SS
    Hepatobiliary Pancreat Dis Int; 2016 Jun; 15(3):289-96. PubMed ID: 27298105
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cyclic AMP inhibits the proliferation of thyroid carcinoma cell lines through regulation of CDK4 phosphorylation.
    Rocha AS; Paternot S; Coulonval K; Dumont JE; Soares P; Roger PP
    Mol Biol Cell; 2008 Nov; 19(11):4814-25. PubMed ID: 18799615
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential requirements for ras and the retinoblastoma tumor suppressor protein in the androgen dependence of prostatic adenocarcinoma cells.
    Fribourg AF; Knudsen KE; Strobeck MW; Lindhorst CM; Knudsen ES
    Cell Growth Differ; 2000 Jul; 11(7):361-72. PubMed ID: 10939590
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF.
    Zhang HS; Gavin M; Dahiya A; Postigo AA; Ma D; Luo RX; Harbour JW; Dean DC
    Cell; 2000 Mar; 101(1):79-89. PubMed ID: 10778858
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Notch1 signaling inhibits growth of human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis.
    Qi R; An H; Yu Y; Zhang M; Liu S; Xu H; Guo Z; Cheng T; Cao X
    Cancer Res; 2003 Dec; 63(23):8323-9. PubMed ID: 14678992
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CD109 Mediates Cell Survival in Hepatocellular Carcinoma Cells.
    Zong G; Xu Z; Zhang S; Shen Y; Qiu H; Zhu G; He S; Tao T; Chen X
    Dig Dis Sci; 2016 Aug; 61(8):2303-2314. PubMed ID: 27074923
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The anticancer activity of the substituted pyridone-annelated isoindigo (5'-Cl) involves G0/G1 cell cycle arrest and inactivation of CDKs in the promyelocytic leukemia cell line HL-60.
    Saleh AM; Aljada A; El-Abadelah MM; Taha MO; Sabri SS; Zahra JA; Aziz MA
    Cell Physiol Biochem; 2015; 35(5):1943-57. PubMed ID: 25870953
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.