BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 33039146)

  • 21. Cyclin D-Cdk4,6 Drives Cell-Cycle Progression via the Retinoblastoma Protein's C-Terminal Helix.
    Topacio BR; Zatulovskiy E; Cristea S; Xie S; Tambo CS; Rubin SM; Sage J; Kõivomägi M; Skotheim JM
    Mol Cell; 2019 May; 74(4):758-770.e4. PubMed ID: 30982746
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Suppressing the CDC37 cochaperone in hepatocellular carcinoma cells inhibits cell cycle progression and cell growth.
    Wang Z; Wei W; Sun CK; Chua MS; So S
    Liver Int; 2015 Apr; 35(4):1403-15. PubMed ID: 25098386
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Estrogen-induced activation of Cdk4 and Cdk2 during G1-S phase progression is accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2.
    Prall OW; Sarcevic B; Musgrove EA; Watts CK; Sutherland RL
    J Biol Chem; 1997 Apr; 272(16):10882-94. PubMed ID: 9099745
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Notch1 is a potential therapeutic target for the treatment of human hepatitis B virus X protein-associated hepatocellular carcinoma.
    Sun Q; Wang R; Wang Y; Luo J; Wang P; Cheng B
    Oncol Rep; 2014 Feb; 31(2):933-9. PubMed ID: 24336972
    [TBL] [Abstract][Full Text] [Related]  

  • 25. PCK1 negatively regulates cell cycle progression and hepatoma cell proliferation via the AMPK/p27
    Tuo L; Xiang J; Pan X; Hu J; Tang H; Liang L; Xia J; Hu Y; Zhang W; Huang A; Wang K; Tang N
    J Exp Clin Cancer Res; 2019 Feb; 38(1):50. PubMed ID: 30717766
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Transient Hysteresis in CDK4/6 Activity Underlies Passage of the Restriction Point in G1.
    Chung M; Liu C; Yang HW; Köberlin MS; Cappell SD; Meyer T
    Mol Cell; 2019 Nov; 76(4):562-573.e4. PubMed ID: 31543423
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Inhibition of Hsp90 function by ansamycins causes retinoblastoma gene product-dependent G1 arrest.
    Srethapakdi M; Liu F; Tavorath R; Rosen N
    Cancer Res; 2000 Jul; 60(14):3940-6. PubMed ID: 10919672
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Cyclic AMP negatively controls c-myc transcription and G1 cell cycle progression in p210 BCR-ABL transformed cells: inhibitory activity exerted through cyclin D1 and cdk4.
    Williamson EA; Burgess GS; Eder P; Litz-Jackson S; Boswell HS
    Leukemia; 1997 Jan; 11(1):73-85. PubMed ID: 9001421
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Cdk4 integrates growth stimulatory and inhibitory signals during G1 phase of hematopoietic cells.
    Ando K; Griffin JD
    Oncogene; 1995 Feb; 10(4):751-5. PubMed ID: 7862452
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Protein expression of p53, p21WAF1, and Rb as prognostic indicators in patients with surgically treated hepatocellular carcinoma.
    Naka T; Toyota N; Kaneko T; Kaibara N
    Anticancer Res; 1998; 18(1B):555-64. PubMed ID: 9568177
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Oncogene RPA1 promotes proliferation of hepatocellular carcinoma via CDK4/Cyclin-D pathway.
    Wang J; Yang T; Chen H; Li H; Zheng S
    Biochem Biophys Res Commun; 2018 Apr; 498(3):424-430. PubMed ID: 29477843
    [TBL] [Abstract][Full Text] [Related]  

  • 32. CDK4/6 inhibitor-SHR6390 exerts potent antitumor activity in esophageal squamous cell carcinoma by inhibiting phosphorylated Rb and inducing G1 cell cycle arrest.
    Wang J; Li Q; Yuan J; Wang J; Chen Z; Liu Z; Li Z; Lai Y; Gao J; Shen L
    J Transl Med; 2017 Jun; 15(1):127. PubMed ID: 28578693
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Cyclin D-CDK4 relieves cooperative repression of proliferation and cell cycle gene expression by DREAM and RB.
    Schade AE; Oser MG; Nicholson HE; DeCaprio JA
    Oncogene; 2019 Jun; 38(25):4962-4976. PubMed ID: 30833638
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Rapamycin inhibits cdk4 activation, p 21(WAF1/CIP1) expression and G1-phase progression in transformed mouse fibroblasts.
    Gaben AM; Saucier C; Bedin M; Barbu V; Mester J
    Int J Cancer; 2004 Jan; 108(2):200-6. PubMed ID: 14639603
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Hypo-phosphorylation of the retinoblastoma protein (pRb) by cyclin D:Cdk4/6 complexes results in active pRb.
    Ezhevsky SA; Nagahara H; Vocero-Akbani AM; Gius DR; Wei MC; Dowdy SF
    Proc Natl Acad Sci U S A; 1997 Sep; 94(20):10699-704. PubMed ID: 9380698
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Transforming growth factor beta(1) selectively inhibits the cyclic AMP-dependent proliferation of primary thyroid epithelial cells by preventing the association of cyclin D3-cdk4 with nuclear p27(kip1).
    Depoortere F; Pirson I; Bartek J; Dumont JE; Roger PP
    Mol Biol Cell; 2000 Mar; 11(3):1061-76. PubMed ID: 10712520
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabine.
    Gelbert LM; Cai S; Lin X; Sanchez-Martinez C; Del Prado M; Lallena MJ; Torres R; Ajamie RT; Wishart GN; Flack RS; Neubauer BL; Young J; Chan EM; Iversen P; Cronier D; Kreklau E; de Dios A
    Invest New Drugs; 2014 Oct; 32(5):825-37. PubMed ID: 24919854
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation.
    Berthet C; Klarmann KD; Hilton MB; Suh HC; Keller JR; Kiyokawa H; Kaldis P
    Dev Cell; 2006 May; 10(5):563-73. PubMed ID: 16678773
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Early G1 growth arrest of hybridoma B cells by DMSO involves cyclin D2 inhibition and p21[CIP1] induction.
    Ponzio G; Loubat A; Rochet N; Turchi L; Rezzonico R; Farahi Far D; Dulic V; Rossi B
    Oncogene; 1998 Sep; 17(9):1159-66. PubMed ID: 9764826
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A Novel Methoxybenzyl 5-Nitroacridone Derivative Effectively Triggers G1 Cell Cycle Arrest in Chronic Myelogenous Leukemia K562 Cells by Inhibiting CDK4/6-Mediated Phosphorylation of Rb.
    Zhang B; Zhang T; Zhang TY; Wang N; He S; Wu B; Jin HX
    Int J Mol Sci; 2020 Jul; 21(14):. PubMed ID: 32708403
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.