These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 33043714)

  • 1. Mechanism-based inactivation of cytochrome P450 enzymes by natural products based on metabolic activation.
    Zhang T; Rao J; Li W; Wang K; Qiu F
    Drug Metab Rev; 2020 Nov; 52(4):501-530. PubMed ID: 33043714
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism-based inactivation of cytochrome P450 enzymes: chemical mechanisms, structure-activity relationships and relationship to clinical drug-drug interactions and idiosyncratic adverse drug reactions.
    Kalgutkar AS; Obach RS; Maurer TS
    Curr Drug Metab; 2007 Jun; 8(5):407-47. PubMed ID: 17584015
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The role of metabolites in predicting drug-drug interactions: focus on irreversible cytochrome P450 inhibition.
    VandenBrink BM; Isoherranen N
    Curr Opin Drug Discov Devel; 2010 Jan; 13(1):66-77. PubMed ID: 20047147
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of CYP2C9 by natural products: insight into the potential risk of herb-drug interactions.
    Wang K; Gao Q; Zhang T; Rao J; Ding L; Qiu F
    Drug Metab Rev; 2020 May; 52(2):235-257. PubMed ID: 32406758
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Multiple modes of inhibition of human cytochrome P450 2J2 by dronedarone, amiodarone and their active metabolites.
    Karkhanis A; Lam HY; Venkatesan G; Koh SK; Chai CL; Zhou L; Hong Y; Kojodjojo P; Chan EC
    Biochem Pharmacol; 2016 May; 107():67-80. PubMed ID: 26972388
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of cytochrome P450 enzymes and biochemical aspects of mechanism-based inactivation (MBI).
    Kamel A; Harriman S
    Drug Discov Today Technol; 2013; 10(1):e177-89. PubMed ID: 24050247
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of cytochrome P450 enzymes and uridine 5'-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions.
    Liu S; Wang Z; Chan E; Zhao Y; Kang J; Zhang X; Tian X
    Chem Biol Interact; 2022 Jan; 352():109775. PubMed ID: 34910929
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metabolic activation of drugs by cytochrome P450 enzymes: Biochemical insights into mechanism-based inactivation by fibroblast growth factor receptor inhibitors and chemical approaches to attenuate reactive metabolite formation.
    Tang LWT; Chan ECY
    Biochem Pharmacol; 2022 Dec; 206():115336. PubMed ID: 36332675
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism-based inactivation of human cytochrome p450 enzymes and the prediction of drug-drug interactions.
    Obach RS; Walsky RL; Venkatakrishnan K
    Drug Metab Dispos; 2007 Feb; 35(2):246-55. PubMed ID: 17093004
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Enzyme Activity of Natural Products on Cytochrome P450.
    Zuo HL; Huang HY; Lin YC; Cai XX; Kong XJ; Luo DL; Zhou YH; Huang HD
    Molecules; 2022 Jan; 27(2):. PubMed ID: 35056827
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human Family 1-4 cytochrome P450 enzymes involved in the metabolic activation of xenobiotic and physiological chemicals: an update.
    Rendic SP; Guengerich FP
    Arch Toxicol; 2021 Feb; 95(2):395-472. PubMed ID: 33459808
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolic interactions of magnolol with cytochrome P450 enzymes: uncompetitive inhibition of CYP1A and competitive inhibition of CYP2C.
    Kim SB; Kang HE; Cho HJ; Kim YS; Chung SJ; Yoon IS; Kim DD
    Drug Dev Ind Pharm; 2016; 42(2):263-9. PubMed ID: 26133083
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Prediction of seriniquinone-drug interactions by in vitro inhibition of human cytochrome P450 enzymes.
    Moreira da Silva R; Carrão DB; Habenschus MD; Jimenez PC; Lopes NP; Fenical W; Costa-Lotufo LV; de Oliveira ARM
    Toxicol In Vitro; 2020 Jun; 65():104820. PubMed ID: 32142840
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanism-Based Inactivation of Cytochrome P450 Enzymes: Computational Insights.
    Mirzaei MS; Ivanov MV; Taherpour AA; Mirzaei S
    Chem Res Toxicol; 2021 Apr; 34(4):959-987. PubMed ID: 33769041
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vitro inhibitory mechanisms and molecular docking of 1'-S-1'-acetoxychavicol acetate on human cytochrome P450 enzymes.
    Haque AKMM; Leong KH; Lo YL; Awang K; Nagoor NH
    Phytomedicine; 2017 Jul; 31():1-9. PubMed ID: 28606510
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanism-based inactivation of human cytochromes p450s: experimental characterization, reactive intermediates, and clinical implications.
    Hollenberg PF; Kent UM; Bumpus NN
    Chem Res Toxicol; 2008 Jan; 21(1):189-205. PubMed ID: 18052110
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cytochrome P450 Structure, Function and Clinical Significance: A Review.
    Manikandan P; Nagini S
    Curr Drug Targets; 2018; 19(1):38-54. PubMed ID: 28124606
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High-throughput cytochrome P450 loss and metabolic intermediate complex assays to aid in designing out of CYP3A inactivation.
    Russell DA; Cerny MA
    Methods Enzymol; 2023; 690():341-368. PubMed ID: 37858534
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reversible and Irreversible Inhibition of Cytochrome P450 Enzymes by Methylophiopogonanone A.
    Tu DZ; Mao X; Zhang F; He RJ; Wu JJ; Wu Y; Zhao XH; Zheng J; Ge GB
    Drug Metab Dispos; 2020 Jun; 49(6):459-469. PubMed ID: 33811108
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Measurement of Cytochrome P450 Enzyme Induction and Inhibition in Human Hepatoma Cells.
    Rodrigues RM; De Kock J; Doktorova TY; Rogiers V; Vanhaecke T
    Methods Mol Biol; 2015; 1250():279-85. PubMed ID: 26272150
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.