BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

240 related articles for article (PubMed ID: 33044977)

  • 1. Structural features and development of an assay platform of the parasite target deoxyhypusine synthase of Brugia malayi and Leishmania major.
    Silva SF; Klippel AH; Ramos PZ; Santiago ADS; Valentini SR; Bengtson MH; Massirer KB; Bilsland E; Couñago RM; Zanelli CF
    PLoS Negl Trop Dis; 2020 Oct; 14(10):e0008762. PubMed ID: 33044977
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Yeast-Based High-Throughput Screens to Identify Novel Compounds Active against Brugia malayi.
    Bilsland E; Bean DM; Devaney E; Oliver SG
    PLoS Negl Trop Dis; 2016 Jan; 10(1):e0004401. PubMed ID: 26812604
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A new non-radioactive deoxyhypusine synthase assay adaptable to high throughput screening.
    Park MH; Mandal A; Mandal S; Wolff EC
    Amino Acids; 2017 Nov; 49(11):1793-1804. PubMed ID: 28819816
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification and characterization of a novel deoxyhypusine synthase in Leishmania donovani.
    Chawla B; Jhingran A; Singh S; Tyagi N; Park MH; Srinivasan N; Roberts SC; Madhubala R
    J Biol Chem; 2010 Jan; 285(1):453-63. PubMed ID: 19880510
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cloning, expression and functional activity of deoxyhypusine synthase from Plasmodium vivax.
    Njuguna JT; Nassar M; Hoerauf A; Kaiser AE
    BMC Microbiol; 2006 Oct; 6():91. PubMed ID: 17042947
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Screening assay for the identification of deoxyhypusine synthase inhibitors.
    Sommer MN; Bevec D; Klebl B; Flicke B; Hölscher K; Freudenreich T; Hauber I; Hauber J; Mett H
    J Biomol Screen; 2004 Aug; 9(5):434-8. PubMed ID: 15296643
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting enzymes involved in spermidine metabolism of parasitic protozoa--a possible new strategy for anti-parasitic treatment.
    Kaiser A; Gottwald A; Maier W; Seitz HM
    Parasitol Res; 2003 Dec; 91(6):508-16. PubMed ID: 14530966
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In silico design, synthesis, and screening of novel deoxyhypusine synthase inhibitors targeting HIV-1 replication.
    Schroeder M; Kolodzik A; Pfaff K; Priyadarshini P; Krepstakies M; Hauber J; Rarey M; Meier C
    ChemMedChem; 2014 May; 9(5):940-52. PubMed ID: 24616161
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evolutionary relationships among protein lysine deacetylases of parasites causing neglected diseases.
    Scholte LLS; Mourão MM; Pais FS; Melesina J; Robaa D; Volpini AC; Sippl W; Pierce RJ; Oliveira G; Nahum LA
    Infect Genet Evol; 2017 Sep; 53():175-188. PubMed ID: 28506839
    [TBL] [Abstract][Full Text] [Related]  

  • 10. UDP-galactopyranose mutase, a potential drug target against human pathogenic nematode Brugia malayi.
    Misra S; Valicherla GR; Mohd Shahab ; Gupta J; Gayen JR; Misra-Bhattacharya S
    Pathog Dis; 2016 Aug; 74(6):. PubMed ID: 27465638
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Target evaluation of deoxyhypusine synthase from Theileria parva the neglected animal parasite and its relationship to Plasmodium.
    Njuguna JT; von Koschitzky I; Gerhardt H; Lämmerhofer M; Choucry A; Pink M; Schmitz-Spahnke S; Bakheit MA; Strube C; Kaiser A
    Bioorg Med Chem; 2014 Aug; 22(15):4338-46. PubMed ID: 24909679
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase.
    Wątor E; Wilk P; Grudnik P
    Biomolecules; 2020 Mar; 10(4):. PubMed ID: 32235505
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development.
    Cavazzuti A; Paglietti G; Hunter WN; Gamarro F; Piras S; Loriga M; Allecca S; Corona P; McLuskey K; Tulloch L; Gibellini F; Ferrari S; Costi MP
    Proc Natl Acad Sci U S A; 2008 Feb; 105(5):1448-53. PubMed ID: 18245389
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Allosteric activation of trypanosomatid deoxyhypusine synthase by a catalytically dead paralog.
    Nguyen S; Jones DC; Wyllie S; Fairlamb AH; Phillips MA
    J Biol Chem; 2013 May; 288(21):15256-67. PubMed ID: 23525104
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Investigation of an Allosteric Deoxyhypusine Synthase Inhibitor in
    Aroonsri A; Wongsombat C; Shaw P; Franke S; Przyborski J; Kaiser A
    Molecules; 2022 Apr; 27(8):. PubMed ID: 35458660
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Trypanosomatid Deoxyhypusine Synthase Activity Is Dependent on Shared Active-Site Complementation between Pseudoenzyme Paralogs.
    Afanador GA; Tomchick DR; Phillips MA
    Structure; 2018 Nov; 26(11):1499-1512.e5. PubMed ID: 30197036
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The guanylhydrazone CNI-1493: an inhibitor with dual activity against malaria-inhibition of host cell pro-inflammatory cytokine release and parasitic deoxyhypusine synthase.
    Specht S; Sarite SR; Hauber I; Hauber J; Görbig UF; Meier C; Bevec D; Hoerauf A; Kaiser A
    Parasitol Res; 2008 May; 102(6):1177-84. PubMed ID: 18256853
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of anti-filarial leads against aspartate semialdehyde dehydrogenase of Wolbachia endosymbiont of Brugia malayi: combined molecular docking and molecular dynamics approaches.
    Amala M; Rajamanikandan S; Prabhu D; Surekha K; Jeyakanthan J
    J Biomol Struct Dyn; 2019 Feb; 37(2):394-410. PubMed ID: 29334340
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Posttranslational synthesis of hypusine: evolutionary progression and specificity of the hypusine modification.
    Wolff EC; Kang KR; Kim YS; Park MH
    Amino Acids; 2007 Aug; 33(2):341-50. PubMed ID: 17476569
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modification of eukaryotic initiation factor 5A from Plasmodium vivax by a truncated deoxyhypusine synthase from Plasmodium falciparum: An enzyme with dual enzymatic properties.
    Kaiser A; Hammels I; Gottwald A; Nassar M; Zaghloul MS; Motaal BA; Hauber J; Hoerauf A
    Bioorg Med Chem; 2007 Sep; 15(18):6200-7. PubMed ID: 17591443
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.