BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 33046605)

  • 1. The F1 loop of the talin head domain acts as a gatekeeper in integrin activation and clustering.
    Kukkurainen S; Azizi L; Zhang P; Jacquier MC; Baikoghli M; von Essen M; Tuukkanen A; Laitaoja M; Liu X; Rahikainen R; Orłowski A; Jänis J; Määttä JAE; Varjosalo M; Vattulainen I; Róg T; Svergun D; Cheng RH; Wu J; Hytönen VP; Wehrle-Haller B
    J Cell Sci; 2020 Oct; 133(19):. PubMed ID: 33046605
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A conserved lipid-binding loop in the kindlin FERM F1 domain is required for kindlin-mediated αIIbβ3 integrin coactivation.
    Bouaouina M; Goult BT; Huet-Calderwood C; Bate N; Brahme NN; Barsukov IL; Critchley DR; Calderwood DA
    J Biol Chem; 2012 Mar; 287(10):6979-90. PubMed ID: 22235127
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins.
    Bouaouina M; Lad Y; Calderwood DA
    J Biol Chem; 2008 Mar; 283(10):6118-25. PubMed ID: 18165225
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structure of the FERM-folded talin head reveals the determinants for integrin binding.
    Zhang P; Azizi L; Kukkurainen S; Gao T; Baikoghli M; Jacquier MC; Sun Y; Määttä JAE; Cheng RH; Wehrle-Haller B; Hytönen VP; Wu J
    Proc Natl Acad Sci U S A; 2020 Dec; 117(51):32402-32412. PubMed ID: 33288722
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Domain-specific interactions of talin with the membrane-proximal region of the integrin beta3 subunit.
    Ulmer TS; Calderwood DA; Ginsberg MH; Campbell ID
    Biochemistry; 2003 Jul; 42(27):8307-12. PubMed ID: 12846579
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The structure of the N-terminus of kindlin-1: a domain important for alphaiibbeta3 integrin activation.
    Goult BT; Bouaouina M; Harburger DS; Bate N; Patel B; Anthis NJ; Campbell ID; Calderwood DA; Barsukov IL; Roberts GC; Critchley DR
    J Mol Biol; 2009 Dec; 394(5):944-56. PubMed ID: 19804783
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The phosphotyrosine binding-like domain of talin activates integrins.
    Calderwood DA; Yan B; de Pereda JM; Alvarez BG; Fujioka Y; Liddington RC; Ginsberg MH
    J Biol Chem; 2002 Jun; 277(24):21749-58. PubMed ID: 11932255
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The extreme C-terminal region of kindlin-2 is critical to its regulation of integrin activation.
    Hirbawi J; Bialkowska K; Bledzka KM; Liu J; Fukuda K; Qin J; Plow EF
    J Biol Chem; 2017 Aug; 292(34):14258-14269. PubMed ID: 28652408
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects.
    Harburger DS; Bouaouina M; Calderwood DA
    J Biol Chem; 2009 Apr; 284(17):11485-97. PubMed ID: 19240021
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
    Goult BT; Bouaouina M; Elliott PR; Bate N; Patel B; Gingras AR; Grossmann JG; Roberts GC; Calderwood DA; Critchley DR; Barsukov IL
    EMBO J; 2010 Mar; 29(6):1069-80. PubMed ID: 20150896
    [TBL] [Abstract][Full Text] [Related]  

  • 11. New PI(4,5)P2- and membrane proximal integrin-binding motifs in the talin head control beta3-integrin clustering.
    Saltel F; Mortier E; Hytönen VP; Jacquier MC; Zimmermann P; Vogel V; Liu W; Wehrle-Haller B
    J Cell Biol; 2009 Nov; 187(5):715-31. PubMed ID: 19948488
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Integrin αII b tail distal of GFFKR participates in inside-out αII b β3 activation.
    Li A; Guo Q; Kim C; Hu W; Ye F
    J Thromb Haemost; 2014 Jul; 12(7):1145-55. PubMed ID: 24837519
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Affinity of talin-1 for the β3-integrin cytosolic domain is modulated by its phospholipid bilayer environment.
    Moore DT; Nygren P; Jo H; Boesze-Battaglia K; Bennett JS; DeGrado WF
    Proc Natl Acad Sci U S A; 2012 Jan; 109(3):793-8. PubMed ID: 22210111
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The talin rod IBS2 alpha-helix interacts with the beta3 integrin cytoplasmic tail membrane-proximal helix by establishing charge complementary salt bridges.
    Rodius S; Chaloin O; Moes M; Schaffner-Reckinger E; Landrieu I; Lippens G; Lin M; Zhang J; Kieffer N
    J Biol Chem; 2008 Aug; 283(35):24212-23. PubMed ID: 18577523
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Integrity of kindlin-2 FERM subdomains is required for supporting integrin activation.
    Xu Z; Gao J; Hong J; Ma YQ
    Biochem Biophys Res Commun; 2013 May; 434(2):382-7. PubMed ID: 23578664
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional and structural characterization of the talin F0F1 domain.
    Domadia PN; Li YF; Bhunia A; Mohanram H; Tan SM; Bhattacharjya S
    Biochem Biophys Res Commun; 2010 Jan; 391(1):159-65. PubMed ID: 19903453
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Talin and kindlin cooperate to control the density of integrin clusters.
    Pernier J; Cardoso Dos Santos M; Souissi M; Joly A; Narassimprakash H; Rossier O; Giannone G; Helfer E; Sengupta K; Le Clainche C
    J Cell Sci; 2023 Apr; 136(8):. PubMed ID: 37083041
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cooperative role of the membrane-proximal and -distal residues of the integrin beta3 cytoplasmic domain in regulation of talin-mediated alpha IIb beta3 activation.
    Hato T; Yamanouchi J; Tamura T; Yakushijin Y; Sakai I; Yasukawa M
    J Biol Chem; 2008 Feb; 283(9):5662-8. PubMed ID: 18174155
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Kindlins, integrin activation and the regulation of talin recruitment to αIIbβ3.
    Kahner BN; Kato H; Banno A; Ginsberg MH; Shattil SJ; Ye F
    PLoS One; 2012; 7(3):e34056. PubMed ID: 22457811
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Conformational changes in talin on binding to anionic phospholipid membranes facilitate signaling by integrin transmembrane helices.
    Kalli AC; Campbell ID; Sansom MS
    PLoS Comput Biol; 2013 Oct; 9(10):e1003316. PubMed ID: 24204243
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.