These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 33050112)

  • 1. Magnolol Enhances the Therapeutic Effects of TRAIL through DR5 Upregulation and Downregulation of c-FLIP and Mcl-1 Proteins in Cancer Cells.
    Woo SM; Min KJ; Kwon TK
    Molecules; 2020 Oct; 25(19):. PubMed ID: 33050112
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Down-regulation of intracellular anti-apoptotic proteins, particularly c-FLIP by therapeutic agents; the novel view to overcome resistance to TRAIL.
    Hassanzadeh A; Farshdousti Hagh M; Alivand MR; Akbari AAM; Shams Asenjan K; Saraei R; Solali S
    J Cell Physiol; 2018 Oct; 233(10):6470-6485. PubMed ID: 29741767
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Monensin, a polyether ionophore antibiotic, overcomes TRAIL resistance in glioma cells via endoplasmic reticulum stress, DR5 upregulation and c-FLIP downregulation.
    Yoon MJ; Kang YJ; Kim IY; Kim EH; Lee JA; Lim JH; Kwon TK; Choi KS
    Carcinogenesis; 2013 Aug; 34(8):1918-28. PubMed ID: 23615398
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Maritoclax Enhances TRAIL-Induced Apoptosis via CHOP-Mediated Upregulation of DR5 and miR-708-Mediated Downregulation of cFLIP.
    Jeon MY; Min KJ; Woo SM; Seo SU; Choi YH; Kim SH; Kim DE; Lee TJ; Kim S; Park JW; Kwon TK
    Molecules; 2018 Nov; 23(11):. PubMed ID: 30463333
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lucanthone, Autophagy Inhibitor, Enhances the Apoptotic Effects of TRAIL through miR-216a-5p-Mediated DR5 Upregulation and DUB3-Mediated Mcl-1 Downregulation.
    Yoon JY; Woo SM; Seo SU; Song SR; Lee SG; Kwon TK
    Int J Mol Sci; 2021 Dec; 23(1):. PubMed ID: 35008442
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ABT-737 induces expression of the death receptor 5 and sensitizes human cancer cells to TRAIL-induced apoptosis.
    Song JH; Kandasamy K; Kraft AS
    J Biol Chem; 2008 Sep; 283(36):25003-13. PubMed ID: 18599488
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells.
    Liu X; Yue P; Chen S; Hu L; Lonial S; Khuri FR; Sun SY
    Cancer Res; 2007 May; 67(10):4981-8. PubMed ID: 17510429
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PPARgamma ligands enhance TRAIL-induced apoptosis through DR5 upregulation and c-FLIP downregulation in human lung cancer cells.
    Zou W; Liu X; Yue P; Khuri FR; Sun SY
    Cancer Biol Ther; 2007 Jan; 6(1):99-106. PubMed ID: 17172826
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antimycin A sensitizes cells to TRAIL-induced apoptosis through upregulation of DR5 and downregulation of c-FLIP and Bcl-2.
    Lee SJ; Kim EA; Song KS; Kim MJ; Lee DH; Kwon TK; Lee TJ
    Int J Oncol; 2012 Oct; 41(4):1425-30. PubMed ID: 22842544
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Berberine sensitizes TRAIL-induced apoptosis through proteasome-mediated downregulation of c-FLIP and Mcl-1 proteins.
    Lee SJ; Noh HJ; Sung EG; Song IH; Kim JY; Kwon TK; Lee TJ
    Int J Oncol; 2011 Feb; 38(2):485-92. PubMed ID: 21170508
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The eIF4E/eIF4G interaction inhibitor 4EGI-1 augments TRAIL-mediated apoptosis through c-FLIP Down-regulation and DR5 induction independent of inhibition of cap-dependent protein translation.
    Fan S; Li Y; Yue P; Khuri FR; Sun SY
    Neoplasia; 2010 Apr; 12(4):346-56. PubMed ID: 20360945
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CCAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction and ubiquitin/proteasome-mediated cellular FLICE-inhibitory protein down-regulation contribute to enhancement of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by dimethyl-celecoxib in human non small-cell lung cancer cells.
    Chen S; Liu X; Yue P; Schönthal AH; Khuri FR; Sun SY
    Mol Pharmacol; 2007 Nov; 72(5):1269-79. PubMed ID: 17684158
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel histone deacetylase inhibitors derived from Magnolia officinalis significantly enhance TRAIL-induced apoptosis in non-small cell lung cancer.
    Liu Y; Tong Y; Yang X; Li F; Zheng L; Liu W; Wu J; Ou R; Zhang G; Hu M; Liu Z; Lu L
    Pharmacol Res; 2016 Sep; 111():113-125. PubMed ID: 27268146
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis.
    Raja SM; Chen S; Yue P; Acker TM; Lefkove B; Arbiser JL; Khuri FR; Sun SY
    Mol Cancer Ther; 2008 Jul; 7(7):2212-23. PubMed ID: 18645030
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Compound C sensitizes Caki renal cancer cells to TRAIL-induced apoptosis through reactive oxygen species-mediated down-regulation of c-FLIPL and Mcl-1.
    Jang JH; Lee TJ; Yang ES; Min do S; Kim YH; Kim SH; Choi YH; Park JW; Choi KS; Kwon TK
    Exp Cell Res; 2010 Aug; 316(13):2194-203. PubMed ID: 20451517
    [TBL] [Abstract][Full Text] [Related]  

  • 16. α-TEA induces apoptosis of human breast cancer cells via activation of TRAIL/DR5 death receptor pathway.
    Yu W; Tiwary R; Li J; Park SK; Jia L; Xiong A; Simmons-Menchaca M; Sanders BG; Kline K
    Mol Carcinog; 2010 Nov; 49(11):964-73. PubMed ID: 20886583
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antipsychotic agent thioridazine sensitizes renal carcinoma Caki cells to TRAIL-induced apoptosis through reactive oxygen species-mediated inhibition of Akt signaling and downregulation of Mcl-1 and c-FLIP(L).
    Min KJ; Seo BR; Bae YC; Yoo YH; Kwon TK
    Cell Death Dis; 2014 Feb; 5(2):e1063. PubMed ID: 24556678
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ER stress sensitizes cells to TRAIL through down-regulation of FLIP and Mcl-1 and PERK-dependent up-regulation of TRAIL-R2.
    Martín-Pérez R; Niwa M; López-Rivas A
    Apoptosis; 2012 Apr; 17(4):349-63. PubMed ID: 22072062
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CRISPR-mediated upregulation of DR5 and downregulation of cFLIP synergistically sensitize HeLa cells to TRAIL-mediated apoptosis.
    Poondla N; Chandrasekaran AP; Heese K; Kim KS; Ramakrishna S
    Biochem Biophys Res Commun; 2019 Apr; 512(1):60-65. PubMed ID: 30862357
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ITCH-dependent proteasomal degradation of c-FLIP induced by the anti-HER3 antibody 9F7-F11 promotes DR5/caspase 8-mediated apoptosis of tumor cells.
    Le Clorennec C; Lazrek Y; Dubreuil O; Sampaio C; Larbouret C; Lanotte R; Poul MA; Barret JM; Prost JF; Pèlegrin A; Chardès T
    Cell Commun Signal; 2019 Aug; 17(1):106. PubMed ID: 31443721
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.