These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

472 related articles for article (PubMed ID: 33060681)

  • 21. Synthesis and biological evaluation of novel 2,4-diaminoquinazoline derivatives as SMN2 promoter activators for the potential treatment of spinal muscular atrophy.
    Thurmond J; Butchbach ME; Palomo M; Pease B; Rao M; Bedell L; Keyvan M; Pai G; Mishra R; Haraldsson M; Andresson T; Bragason G; Thosteinsdottir M; Bjornsson JM; Coovert DD; Burghes AH; Gurney ME; Singh J
    J Med Chem; 2008 Feb; 51(3):449-69. PubMed ID: 18205293
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Mechanism of Splicing Regulation of Spinal Muscular Atrophy Genes.
    Singh RN; Singh NN
    Adv Neurobiol; 2018; 20():31-61. PubMed ID: 29916015
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Enhancement of SMN protein levels in a mouse model of spinal muscular atrophy using novel drug-like compounds.
    Cherry JJ; Osman EY; Evans MC; Choi S; Xing X; Cuny GD; Glicksman MA; Lorson CL; Androphy EJ
    EMBO Mol Med; 2013 Jul; 5(7):1103-18. PubMed ID: 23740718
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Combinatorial treatment for spinal muscular atrophy: An Editorial for 'Combined treatment with the histone deacetylase inhibitor LBH589 and a splice-switch antisense oligonucleotide enhances SMN2 splicing and SMN expression in Spinal Muscular Atrophy cells' on page 264.
    Poletti A; Fischbeck KH
    J Neurochem; 2020 Apr; 153(2):146-149. PubMed ID: 32056234
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Genomic Variability in the Survival Motor Neuron Genes (
    Butchbach MER
    Int J Mol Sci; 2021 Jul; 22(15):. PubMed ID: 34360669
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Optimization of SMN trans-splicing through the analysis of SMN introns.
    Shababi M; Lorson CL
    J Mol Neurosci; 2012 Mar; 46(3):459-69. PubMed ID: 21826391
    [TBL] [Abstract][Full Text] [Related]  

  • 27. A negatively acting bifunctional RNA increases survival motor neuron both in vitro and in vivo.
    Dickson A; Osman E; Lorson CL
    Hum Gene Ther; 2008 Nov; 19(11):1307-15. PubMed ID: 19848583
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Advances in therapeutic development for spinal muscular atrophy.
    Howell MD; Singh NN; Singh RN
    Future Med Chem; 2014 Jun; 6(9):1081-99. PubMed ID: 25068989
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Discovery of Small Molecule Splicing Modulators of Survival Motor Neuron-2 (SMN2) for the Treatment of Spinal Muscular Atrophy (SMA).
    Cheung AK; Hurley B; Kerrigan R; Shu L; Chin DN; Shen Y; O'Brien G; Sung MJ; Hou Y; Axford J; Cody E; Sun R; Fazal A; Fridrich C; Sanchez CC; Tomlinson RC; Jain M; Deng L; Hoffmaster K; Song C; Van Hoosear M; Shin Y; Servais R; Towler C; Hild M; Curtis D; Dietrich WF; Hamann LG; Briner K; Chen KS; Kobayashi D; Sivasankaran R; Dales NA
    J Med Chem; 2018 Dec; 61(24):11021-11036. PubMed ID: 30407821
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Tetracyclines that promote SMN2 exon 7 splicing as therapeutics for spinal muscular atrophy.
    Hastings ML; Berniac J; Liu YH; Abato P; Jodelka FM; Barthel L; Kumar S; Dudley C; Nelson M; Larson K; Edmonds J; Bowser T; Draper M; Higgins P; Krainer AR
    Sci Transl Med; 2009 Nov; 1(5):5ra12. PubMed ID: 20161659
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Development and characterization of an SMN2-based intermediate mouse model of Spinal Muscular Atrophy.
    Cobb MS; Rose FF; Rindt H; Glascock JJ; Shababi M; Miller MR; Osman EY; Yen PF; Garcia ML; Martin BR; Wetz MJ; Mazzasette C; Feng Z; Ko CP; Lorson CL
    Hum Mol Genet; 2013 May; 22(9):1843-55. PubMed ID: 23390132
    [TBL] [Abstract][Full Text] [Related]  

  • 32. SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy.
    Riessland M; Ackermann B; Förster A; Jakubik M; Hauke J; Garbes L; Fritzsche I; Mende Y; Blumcke I; Hahnen E; Wirth B
    Hum Mol Genet; 2010 Apr; 19(8):1492-506. PubMed ID: 20097677
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The Antisense Transcript SMN-AS1 Regulates SMN Expression and Is a Novel Therapeutic Target for Spinal Muscular Atrophy.
    d'Ydewalle C; Ramos DM; Pyles NJ; Ng SY; Gorz M; Pilato CM; Ling K; Kong L; Ward AJ; Rubin LL; Rigo F; Bennett CF; Sumner CJ
    Neuron; 2017 Jan; 93(1):66-79. PubMed ID: 28017471
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Real-world evidence: Risdiplam in a patient with spinal muscular atrophy type I with a novel splicing mutation and one SMN2 copy.
    Ma K; Zhang K; Chen D; Wang C; Abdalla M; Zhang H; Tian R; Liu Y; Song L; Zhang X; Liu F; Liu G; Wang D
    Hum Mol Genet; 2024 Jun; 33(13):1120-1130. PubMed ID: 38520738
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Nusinersen in the Treatment of Spinal Muscular Atrophy.
    Goodkey K; Aslesh T; Maruyama R; Yokota T
    Methods Mol Biol; 2018; 1828():69-76. PubMed ID: 30171535
    [TBL] [Abstract][Full Text] [Related]  

  • 36. RNA in spinal muscular atrophy: therapeutic implications of targeting.
    Singh RN; Seo J; Singh NN
    Expert Opin Ther Targets; 2020 Aug; 24(8):731-743. PubMed ID: 32538213
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Revealing diverse alternative splicing variants of the highly homologous SMN1 and SMN2 genes by targeted long-read sequencing.
    Dai M; Xu Y; Sun Y; Xiao B; Ying X; Liu Y; Jiang W; Zhang J; Liu X; Ji X
    Mol Genet Genomics; 2022 Jul; 297(4):1039-1048. PubMed ID: 35612622
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Oxidative Stress Triggers Body-Wide Skipping of Multiple Exons of the Spinal Muscular Atrophy Gene.
    Seo J; Singh NN; Ottesen EW; Sivanesan S; Shishimorova M; Singh RN
    PLoS One; 2016; 11(4):e0154390. PubMed ID: 27111068
    [TBL] [Abstract][Full Text] [Related]  

  • 39. ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy.
    Kannan A; Jiang X; He L; Ahmad S; Gangwani L
    Brain; 2020 Jan; 143(1):69-93. PubMed ID: 31828288
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Nusinersen: A Review in 5q Spinal Muscular Atrophy.
    Hoy SM
    CNS Drugs; 2021 Dec; 35(12):1317-1328. PubMed ID: 34850360
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 24.