BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

231 related articles for article (PubMed ID: 33064315)

  • 1. Mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex.
    Dyer MS; Reale LA; Lewis KE; Walker AK; Dickson TC; Woodhouse A; Blizzard CA
    J Neurochem; 2021 May; 157(4):1300-1315. PubMed ID: 33064315
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pathologically mislocalised TDP-43 in upper motor neurons causes a die-forward spread of ALS-like pathogenic changes throughout the mouse corticomotor system.
    Reale LA; Dyer MS; Perry SE; Young KM; Dickson TC; Woodhouse A; Blizzard CA
    Prog Neurobiol; 2023 Jul; 226():102449. PubMed ID: 37011806
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo.
    Williamson MG; Finelli MJ; Sleigh JN; Reddington A; Gordon D; Talbot K; Davies KE; Oliver PL
    Hum Mol Genet; 2019 Nov; 28(21):3584-3599. PubMed ID: 31642482
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis.
    Estes PS; Daniel SG; McCallum AP; Boehringer AV; Sukhina AS; Zwick RA; Zarnescu DC
    Dis Model Mech; 2013 May; 6(3):721-33. PubMed ID: 23471911
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TDP-43 expression in mouse models of amyotrophic lateral sclerosis and spinal muscular atrophy.
    Turner BJ; Bäumer D; Parkinson NJ; Scaber J; Ansorge O; Talbot K
    BMC Neurosci; 2008 Oct; 9():104. PubMed ID: 18957104
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Altered Functionality, Morphology, and Vesicular Glutamate Transporter Expression of Cortical Motor Neurons from a Presymptomatic Mouse Model of Amyotrophic Lateral Sclerosis.
    Saba L; Viscomi MT; Caioli S; Pignataro A; Bisicchia E; Pieri M; Molinari M; Ammassari-Teule M; Zona C
    Cereb Cortex; 2016 Apr; 26(4):1512-28. PubMed ID: 25596588
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Stress-Specific Spatiotemporal Responses of RNA-Binding Proteins in Human Stem-Cell-Derived Motor Neurons.
    Harley J; Patani R
    Int J Mol Sci; 2020 Nov; 21(21):. PubMed ID: 33172210
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction.
    Gordon D; Dafinca R; Scaber J; Alegre-Abarrategui J; Farrimond L; Scott C; Biggs D; Kent L; Oliver PL; Davies B; Ansorge O; Wade-Martins R; Talbot K
    Neurobiol Dis; 2019 Jan; 121():148-162. PubMed ID: 30290270
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cytoplasmic Human TDP-43 Mislocalization Induces Widespread Dendritic Spine Loss in Mouse Upper Motor Neurons.
    Dyer MS; Woodhouse A; Blizzard CA
    Brain Sci; 2021 Jun; 11(7):. PubMed ID: 34209287
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS.
    Mitchell JC; Constable R; So E; Vance C; Scotter E; Glover L; Hortobagyi T; Arnold ES; Ling SC; McAlonis M; Da Cruz S; Polymenidou M; Tessarolo L; Cleveland DW; Shaw CE
    Acta Neuropathol Commun; 2015 Jun; 3():36. PubMed ID: 26108367
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth.
    Fallini C; Bassell GJ; Rossoll W
    Hum Mol Genet; 2012 Aug; 21(16):3703-18. PubMed ID: 22641816
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Amyotrophic lateral sclerosis mutant TDP-43 may cause synaptic dysfunction through altered dendritic spine function.
    Jiang T; Handley E; Brizuela M; Dawkins E; Lewis KEA; Clark RM; Dickson TC; Blizzard CA
    Dis Model Mech; 2019 May; 12(5):. PubMed ID: 31036551
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis.
    Ishihara T; Ariizumi Y; Shiga A; Kato T; Tan CF; Sato T; Miki Y; Yokoo M; Fujino T; Koyama A; Yokoseki A; Nishizawa M; Kakita A; Takahashi H; Onodera O
    Hum Mol Genet; 2013 Oct; 22(20):4136-47. PubMed ID: 23740936
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss.
    White MA; Lin Z; Kim E; Henstridge CM; Pena Altamira E; Hunt CK; Burchill E; Callaghan I; Loreto A; Brown-Wright H; Mead R; Simmons C; Cash D; Coleman MP; Sreedharan J
    Acta Neuropathol Commun; 2019 Oct; 7(1):166. PubMed ID: 31661035
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pathological TDP-43 changes in Betz cells differ from those in bulbar and spinal α-motoneurons in sporadic amyotrophic lateral sclerosis.
    Braak H; Ludolph AC; Neumann M; Ravits J; Del Tredici K
    Acta Neuropathol; 2017 Jan; 133(1):79-90. PubMed ID: 27757524
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tar DNA-binding protein-43 (TDP-43) regulates axon growth in vitro and in vivo.
    Tripathi VB; Baskaran P; Shaw CE; Guthrie S
    Neurobiol Dis; 2014 May; 65(100):25-34. PubMed ID: 24423647
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synaptic remodeling follows upper motor neuron hyperexcitability in a rodent model of TDP-43.
    Dyer MS; Odierna GL; Clark RM; Woodhouse A; Blizzard CA
    Front Cell Neurosci; 2023; 17():1274979. PubMed ID: 37941604
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TDP-43 redistribution is an early event in sporadic amyotrophic lateral sclerosis.
    Giordana MT; Piccinini M; Grifoni S; De Marco G; Vercellino M; Magistrello M; Pellerino A; Buccinnà B; Lupino E; Rinaudo MT
    Brain Pathol; 2010 Mar; 20(2):351-60. PubMed ID: 19338576
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Protein Disulfide Isomerase Endoplasmic Reticulum Protein 57 (ERp57) is Protective Against ALS-Associated Mutant TDP-43 in Neuronal Cells.
    Parakh S; Perri ER; Vidal M; Takalloo Z; Jagaraj CJ; Mehta P; Yang S; Thomas CJ; Blair IP; Hong Y; Atkin JD
    Neuromolecular Med; 2024 Jun; 26(1):23. PubMed ID: 38861223
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cortical synaptic and dendritic spine abnormalities in a presymptomatic TDP-43 model of amyotrophic lateral sclerosis.
    Fogarty MJ; Klenowski PM; Lee JD; Drieberg-Thompson JR; Bartlett SE; Ngo ST; Hilliard MA; Bellingham MC; Noakes PG
    Sci Rep; 2016 Nov; 6():37968. PubMed ID: 27897242
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.