160 related articles for article (PubMed ID: 33064845)
1. Ciliary localization of folliculin mediated via a kinesin-2-binding motif is required for its functions in mTOR regulation and tumor suppression.
Zhang Y; Liu Y; Dai Y; Ren Y; Bao G; Ai B; Jiang Y
FEBS Lett; 2021 Jan; 595(1):123-132. PubMed ID: 33064845
[TBL] [Abstract][Full Text] [Related]
2. Tumor Suppressor Folliculin Regulates mTORC1 through Primary Cilia.
Zhong M; Zhao X; Li J; Yuan W; Yan G; Tong M; Guo S; Zhu Y; Jiang Y; Liu Y; Jiang Y
J Biol Chem; 2016 May; 291(22):11689-97. PubMed ID: 27072130
[TBL] [Abstract][Full Text] [Related]
3. Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases.
Petit CS; Roczniak-Ferguson A; Ferguson SM
J Cell Biol; 2013 Sep; 202(7):1107-22. PubMed ID: 24081491
[TBL] [Abstract][Full Text] [Related]
4. The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue.
Wada S; Neinast M; Jang C; Ibrahim YH; Lee G; Babu A; Li J; Hoshino A; Rowe GC; Rhee J; Martina JA; Puertollano R; Blenis J; Morley M; Baur JA; Seale P; Arany Z
Genes Dev; 2016 Nov; 30(22):2551-2564. PubMed ID: 27913603
[TBL] [Abstract][Full Text] [Related]
5. Nutrient-induced FNIP degradation by SCFβ-TRCP regulates FLCN complex localization and promotes renal cancer progression.
Nagashima K; Fukushima H; Shimizu K; Yamada A; Hidaka M; Hasumi H; Ikebe T; Fukumoto S; Okabe K; Inuzuka H
Oncotarget; 2017 Feb; 8(6):9947-9960. PubMed ID: 28039480
[TBL] [Abstract][Full Text] [Related]
6. Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling.
Baba M; Hong SB; Sharma N; Warren MB; Nickerson ML; Iwamatsu A; Esposito D; Gillette WK; Hopkins RF; Hartley JL; Furihata M; Oishi S; Zhen W; Burke TR; Linehan WM; Schmidt LS; Zbar B
Proc Natl Acad Sci U S A; 2006 Oct; 103(42):15552-7. PubMed ID: 17028174
[TBL] [Abstract][Full Text] [Related]
7. FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation.
Dunlop EA; Seifan S; Claessens T; Behrends C; Kamps MA; Rozycka E; Kemp AJ; Nookala RK; Blenis J; Coull BJ; Murray JT; van Steensel MA; Wilkinson S; Tee AR
Autophagy; 2014 Oct; 10(10):1749-60. PubMed ID: 25126726
[TBL] [Abstract][Full Text] [Related]
8. Birt-Hogg-Dube syndrome is a novel ciliopathy.
Luijten MN; Basten SG; Claessens T; Vernooij M; Scott CL; Janssen R; Easton JA; Kamps MA; Vreeburg M; Broers JL; van Geel M; Menko FH; Harbottle RP; Nookala RK; Tee AR; Land SC; Giles RH; Coull BJ; van Steensel MA
Hum Mol Genet; 2013 Nov; 22(21):4383-97. PubMed ID: 23784378
[TBL] [Abstract][Full Text] [Related]
9. Regulation of folliculin (the BHD gene product) phosphorylation by Tsc2-mTOR pathway.
Piao X; Kobayashi T; Wang L; Shiono M; Takagi Y; Sun G; Abe M; Hagiwara Y; Zhang D; Okimoto K; Kouchi M; Matsumoto I; Hino O
Biochem Biophys Res Commun; 2009 Nov; 389(1):16-21. PubMed ID: 19695222
[TBL] [Abstract][Full Text] [Related]
10. Birt-Hogg-Dubé syndrome: Clinical and molecular aspects of recently identified kidney cancer syndrome.
Hasumi H; Baba M; Hasumi Y; Furuya M; Yao M
Int J Urol; 2016 Mar; 23(3):204-10. PubMed ID: 26608100
[TBL] [Abstract][Full Text] [Related]
11. Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex.
Lawrence RE; Fromm SA; Fu Y; Yokom AL; Kim DJ; Thelen AM; Young LN; Lim CY; Samelson AJ; Hurley JH; Zoncu R
Science; 2019 Nov; 366(6468):971-977. PubMed ID: 31672913
[TBL] [Abstract][Full Text] [Related]
12. FLCN Maintains the Leucine Level in Lysosome to Stimulate mTORC1.
Wu X; Zhao L; Chen Z; Ji X; Qiao X; Jin Y; Liu W
PLoS One; 2016; 11(6):e0157100. PubMed ID: 27280402
[TBL] [Abstract][Full Text] [Related]
13. Acute Inhibition of Heterotrimeric Kinesin-2 Function Reveals Mechanisms of Intraflagellar Transport in Mammalian Cilia.
Engelke MF; Waas B; Kearns SE; Suber A; Boss A; Allen BL; Verhey KJ
Curr Biol; 2019 Apr; 29(7):1137-1148.e4. PubMed ID: 30905605
[TBL] [Abstract][Full Text] [Related]
14. AMPK promotes induction of the tumor suppressor FLCN through activation of TFEB independently of mTOR.
Collodet C; Foretz M; Deak M; Bultot L; Metairon S; Viollet B; Lefebvre G; Raymond F; Parisi A; Civiletto G; Gut P; Descombes P; Sakamoto K
FASEB J; 2019 Nov; 33(11):12374-12391. PubMed ID: 31404503
[TBL] [Abstract][Full Text] [Related]
15. Hedgehog-induced ciliary trafficking of kinesin-4 motor KIF7 requires intraflagellar transport but not KIF7's microtubule binding.
Yue Y; Engelke MF; Blasius TL; Verhey KJ
Mol Biol Cell; 2022 Jan; 33(1):br1. PubMed ID: 34705483
[TBL] [Abstract][Full Text] [Related]
16. Birt-Hogg-Dubé: tumour suppressor function and signalling dynamics central to folliculin.
Tee AR; Pause A
Fam Cancer; 2013 Sep; 12(3):367-72. PubMed ID: 23096221
[TBL] [Abstract][Full Text] [Related]
17. Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion.
Medvetz DA; Khabibullin D; Hariharan V; Ongusaha PP; Goncharova EA; Schlechter T; Darling TN; Hofmann I; Krymskaya VP; Liao JK; Huang H; Henske EP
PLoS One; 2012; 7(11):e47842. PubMed ID: 23139756
[TBL] [Abstract][Full Text] [Related]
18. Unique mutation, accelerated mTOR signaling and angiogenesis in the pulmonary cysts of Birt-Hogg-Dubé syndrome.
Nishii T; Tanabe M; Tanaka R; Matsuzawa T; Okudela K; Nozawa A; Nakatani Y; Furuya M
Pathol Int; 2013 Jan; 63(1):45-55. PubMed ID: 23356225
[TBL] [Abstract][Full Text] [Related]
19. Birt Hogg-Dubé syndrome-associated FLCN mutations disrupt protein stability.
Nahorski MS; Reiman A; Lim DH; Nookala RK; Seabra L; Lu X; Fenton J; Boora U; Nordenskjöld M; Latif F; Hurst LD; Maher ER
Hum Mutat; 2011 Aug; 32(8):921-9. PubMed ID: 21538689
[TBL] [Abstract][Full Text] [Related]
20. Role of FLCN Phosphorylation in Insulin-Mediated mTORC1 Activation and Tumorigenesis.
Wang G; Chen L; Lei X; Qin S; Geng H; Zheng Y; Xia C; Yao J; Meng T; Deng L
Adv Sci (Weinh); 2023 Jun; 10(17):e2206826. PubMed ID: 37083230
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]