347 related articles for article (PubMed ID: 33065122)
1. An innovative method for characterizing neutralizing antibodies against antibody-derived therapeutics.
Coddens A; Snoeck V; Bontinck L; Buyse MA; Pine SO
J Immunol Methods; 2020 Dec; 487():112896. PubMed ID: 33065122
[TBL] [Abstract][Full Text] [Related]
2. Comparison of cell-based and non-cell-based assay platforms for the detection of clinically relevant anti-drug neutralizing antibodies for immunogenicity assessment of therapeutic proteins.
Hu J; Wala I; Han H; Nagatani J; Barger T; Civoli F; Kaliyaperumal A; Zhuang Y; Gupta S
J Immunol Methods; 2015 Apr; 419():1-8. PubMed ID: 25795420
[TBL] [Abstract][Full Text] [Related]
3. Recommendations for the characterization of immunogenicity response to multiple domain biotherapeutics.
Gorovits B; Wakshull E; Pillutla R; Xu Y; Manning MS; Goyal J
J Immunol Methods; 2014 Jun; 408():1-12. PubMed ID: 24861938
[TBL] [Abstract][Full Text] [Related]
4. Neutralizing Antibody Assay Development with High Drug and Target Tolerance to Support Clinical Development of an Anti-TFPI Therapeutic Monoclonal Antibody.
Xiang Y; Parng C; Olson K; Seletskaia E; Gorovits B; Jani D; Caiazzo T; Joyce A; Donley J
AAPS J; 2019 Mar; 21(3):46. PubMed ID: 30927117
[TBL] [Abstract][Full Text] [Related]
5. An immunoinhibition approach to overcome the impact of pre-existing antibodies on cut point establishment for immunogenicity assessment of moxetumomab pasudotox.
Schneider AK; Vainshtein I; Roskos LK; Chavez C; Sun B; Liang M
J Immunol Methods; 2016 Aug; 435():68-76. PubMed ID: 27220271
[TBL] [Abstract][Full Text] [Related]
6. The Immunogenicity of Biologic Therapies.
Garcês S; Demengeot J
Curr Probl Dermatol; 2018; 53():37-48. PubMed ID: 29131036
[TBL] [Abstract][Full Text] [Related]
7. Comparison of competitive ligand-binding assay and bioassay formats for the measurement of neutralizing antibodies to protein therapeutics.
Finco D; Baltrukonis D; Clements-Egan A; Delaria K; Gunn GR; Lowe J; Maia M; Wong T
J Pharm Biomed Anal; 2011 Jan; 54(2):351-8. PubMed ID: 20863644
[TBL] [Abstract][Full Text] [Related]
8. An innovative and highly drug-tolerant approach for detecting neutralizing antibodies directed to therapeutic antibodies.
Sloan JH; Conway RG; Pottanat TG; Troutt JS; Higgs RE; Konrad RJ; Qian YW
Bioanalysis; 2016 Oct; 8(20):2157-68. PubMed ID: 27593891
[TBL] [Abstract][Full Text] [Related]
9. Selection of a Ligand-Binding Neutralizing Antibody Assay for Benralizumab: Comparison with an Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) Cell-Based Assay.
Wu Y; Akhgar A; Li JJ; Yu B; Chen C; Lee N; White WI; Roskos LK
AAPS J; 2018 Mar; 20(3):49. PubMed ID: 29541868
[TBL] [Abstract][Full Text] [Related]
10. Identification and elimination of target-related matrix interference in a neutralizing anti-drug antibody assay.
Schwickart M; Mehrzai F; Pearson J; Shaghasi N; Chavez C; Schneider A; Wu S; Roskos L; Liang M
J Immunol Methods; 2014 Jan; 403(1-2):52-61. PubMed ID: 24287421
[TBL] [Abstract][Full Text] [Related]
11. Addressing soluble target interference in the development of a functional assay for the detection of neutralizing antibodies against a BCMA-CD3 bispecific antibody.
Wang Y; Luong M; Guadiz C; Zhang M; Gorovits B
J Immunol Methods; 2019 Nov; 474():112642. PubMed ID: 31400410
[TBL] [Abstract][Full Text] [Related]
12. Development and characterization of a pre-treatment procedure to eliminate human monoclonal antibody therapeutic drug and matrix interference in cell-based functional neutralizing antibody assays.
Xu W; Jiang H; Titsch C; Haulenbeek JR; Pillutla RC; Aubry AF; DeSilva BS; Arnold ME; Zeng J; Dodge RW
J Immunol Methods; 2015 Jan; 416():94-104. PubMed ID: 25445325
[TBL] [Abstract][Full Text] [Related]
13. Drug Target Interference in Immunogenicity Assays: Recommendations and Mitigation Strategies.
Zhong ZD; Clements-Egan A; Gorovits B; Maia M; Sumner G; Theobald V; Wu Y; Rajadhyaksha M
AAPS J; 2017 Nov; 19(6):1564-1575. PubMed ID: 29063411
[TBL] [Abstract][Full Text] [Related]
14. Development of a Cell-Based Assay for the Detection of Neutralizing Antibodies to PF-06730512 Using Homogenous Time-Resolved Fluorescence.
Luong M; Wang Y; Berasi SP; Buhlmann JE; Yang H; Gorovits B
AAPS J; 2020 Mar; 22(2):56. PubMed ID: 32166588
[TBL] [Abstract][Full Text] [Related]
15. A systematic study of the effect of low pH acid treatment on anti-drug antibodies specific for a domain antibody therapeutic: Impact on drug tolerance, assay sensitivity and post-validation method assessment of ADA in clinical serum samples.
Kavita U; Duo J; Crawford SM; Liu R; Valcin J; Gleason C; Dong H; Gadkari S; Dodge RW; Pillutla RC; DeSilva BS
J Immunol Methods; 2017 Sep; 448():91-104. PubMed ID: 28625864
[TBL] [Abstract][Full Text] [Related]
16. Strategies to Determine Assay Format for the Assessment of Neutralizing Antibody Responses to Biotherapeutics.
Wu B; Chung S; Jiang XR; McNally J; Pedras-Vasconcelos J; Pillutla R; White JT; Xu Y; Gupta S
AAPS J; 2016 Nov; 18(6):1335-1350. PubMed ID: 27495119
[TBL] [Abstract][Full Text] [Related]
17. Approaches to Resolve False Reporting in Neutralizing Antibody Assays Caused by Reagent Leaching from Affinity Capture Elution Solid Phase.
Xiang Y; Kamerud J; Donley J; Olson K; Caiazzo T; Yeung D; Parng C; Gorovits B
AAPS J; 2018 Nov; 21(1):4. PubMed ID: 30402825
[TBL] [Abstract][Full Text] [Related]
18. Assay development considerations to improve drug tolerance in direct competitive ligand binding neutralizing antibody assays, pretreatment strategies.
Rathi A; Rinker S; Niu H; Carter C; Kumar S; Cowan K
J Immunol Methods; 2023 Jun; 517():113484. PubMed ID: 37116778
[TBL] [Abstract][Full Text] [Related]
19. A competitive ligand binding assay for detection of neutralizing antibodies against an insulin analog.
Peek VL; Lemen DM; Konrad RJ; Wen Y
J Immunol Methods; 2023 Dec; 523():113575. PubMed ID: 37844794
[TBL] [Abstract][Full Text] [Related]
20. Indirect assessment of neutralizing anti-drug antibodies utilizing pharmacokinetic assay data.
Vettermann C; Ortiz J; Lee S; Sanchez S; Victor HP; Ma M; Heath T; Gupta S
J Immunol Methods; 2016 Feb; 429():28-38. PubMed ID: 26711311
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
