These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

230 related articles for article (PubMed ID: 33067269)

  • 1. The Functional Landscape of Patient-Derived RNF43 Mutations Predicts Sensitivity to Wnt Inhibition.
    Yu J; Yusoff PAM; Woutersen DTJ; Goh P; Harmston N; Smits R; Epstein DM; Virshup DM; Madan B
    Cancer Res; 2020 Dec; 80(24):5619-5632. PubMed ID: 33067269
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma.
    Jiang X; Hao HX; Growney JD; Woolfenden S; Bottiglio C; Ng N; Lu B; Hsieh MH; Bagdasarian L; Meyer R; Smith TR; Avello M; Charlat O; Xie Y; Porter JA; Pan S; Liu J; McLaughlin ME; Cong F
    Proc Natl Acad Sci U S A; 2013 Jul; 110(31):12649-54. PubMed ID: 23847203
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RNF43 R117fs mutant positively regulates Wnt/β-catenin signaling by failing to internalize FZD expressed on the cell surface.
    Cho AR; Sul HJ; Kim YJ; Kim B; Zang DY
    Sci Rep; 2022 Apr; 12(1):7013. PubMed ID: 35487932
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Commonly observed RNF43 mutations retain functionality in attenuating Wnt/β-catenin signaling and unlikely confer Wnt-dependency onto colorectal cancers.
    Li S; Lavrijsen M; Bakker A; Magierowski M; Magierowska K; Liu P; Wang W; Peppelenbosch MP; Smits R
    Oncogene; 2020 Apr; 39(17):3458-3472. PubMed ID: 32103169
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of RNF43 frameshift mutations that drive Wnt ligand- and R-spondin-dependent colon cancer.
    Yamamoto D; Oshima H; Wang D; Takeda H; Kita K; Lei X; Nakayama M; Murakami K; Ohama T; Takemura H; Toyota M; Suzuki H; Inaki N; Oshima M
    J Pathol; 2022 May; 257(1):39-52. PubMed ID: 35040131
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.
    Spit M; Fenderico N; Jordens I; Radaszkiewicz T; Lindeboom RG; Bugter JM; Cristobal A; Ootes L; van Osch M; Janssen E; Boonekamp KE; Hanakova K; Potesil D; Zdrahal Z; Boj SF; Medema JP; Bryja V; Koo BK; Vermeulen M; Maurice MM
    EMBO J; 2020 Sep; 39(18):e103932. PubMed ID: 32965059
    [TBL] [Abstract][Full Text] [Related]  

  • 7. E3 ligases RNF43 and ZNRF3 display differential specificity for endocytosis of Frizzled receptors.
    Bugter JM; van Kerkhof P; Jordens I; Janssen E; Tran Ngoc Minh T; Iglesias van Montfort D; Jamieson C; Maurice MM
    Life Sci Alliance; 2024 Sep; 7(9):. PubMed ID: 38969364
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis.
    Bond CE; McKeone DM; Kalimutho M; Bettington ML; Pearson SA; Dumenil TD; Wockner LF; Burge M; Leggett BA; Whitehall VL
    Oncotarget; 2016 Oct; 7(43):70589-70600. PubMed ID: 27661107
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular Role of RNF43 in Canonical and Noncanonical Wnt Signaling.
    Tsukiyama T; Fukui A; Terai S; Fujioka Y; Shinada K; Takahashi H; Yamaguchi TP; Ohba Y; Hatakeyama S
    Mol Cell Biol; 2015 Jun; 35(11):2007-23. PubMed ID: 25825523
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protease associated domain of RNF43 is not necessary for the suppression of Wnt/β-catenin signaling in human cells.
    Radaszkiewicz T; Bryja V
    Cell Commun Signal; 2020 Jun; 18(1):91. PubMed ID: 32527265
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The most common RNF43 mutant G659Vfs*41 is fully functional in inhibiting Wnt signaling and unlikely to play a role in tumorigenesis.
    Tu J; Park S; Yu W; Zhang S; Wu L; Carmon K; Liu QJ
    Sci Rep; 2019 Dec; 9(1):18557. PubMed ID: 31811196
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.
    Koo BK; Spit M; Jordens I; Low TY; Stange DE; van de Wetering M; van Es JH; Mohammed S; Heck AJ; Maurice MM; Clevers H
    Nature; 2012 Aug; 488(7413):665-9. PubMed ID: 22895187
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dishevelled promotes Wnt receptor degradation through recruitment of ZNRF3/RNF43 E3 ubiquitin ligases.
    Jiang X; Charlat O; Zamponi R; Yang Y; Cong F
    Mol Cell; 2015 May; 58(3):522-33. PubMed ID: 25891077
    [TBL] [Abstract][Full Text] [Related]  

  • 14. eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants.
    Thornton AM; Fang L; Lo A; McSharry M; Haan D; O'Brien C; Berger AH; Giannakis M; Brooks AN
    PLoS Comput Biol; 2021 Jul; 17(7):e1009132. PubMed ID: 34214079
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RNF43 is mutated less frequently in Lynch Syndrome compared with sporadic microsatellite unstable colorectal cancers.
    Fennell LJ; Clendenning M; McKeone DM; Jamieson SH; Balachandran S; Borowsky J; Liu J; Kawamata F; Bond CE; Rosty C; Burge ME; Buchanan DD; Leggett BA; Whitehall VLJ
    Fam Cancer; 2018 Jan; 17(1):63-69. PubMed ID: 28573495
    [TBL] [Abstract][Full Text] [Related]  

  • 16. USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds.
    Madan B; Walker MP; Young R; Quick L; Orgel KA; Ryan M; Gupta P; Henrich IC; Ferrer M; Marine S; Roberts BS; Arthur WT; Berndt JD; Oliveira AM; Moon RT; Virshup DM; Chou MM; Major MB
    Proc Natl Acad Sci U S A; 2016 May; 113(21):E2945-54. PubMed ID: 27162353
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia.
    Koo BK; van Es JH; van den Born M; Clevers H
    Proc Natl Acad Sci U S A; 2015 Jun; 112(24):7548-50. PubMed ID: 26023187
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rnf43.
    Serra S; Chetty R
    J Clin Pathol; 2018 Jan; 71(1):1-6. PubMed ID: 29018044
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of endogenous RNF43 function enhances proliferation and tumour growth of intestinal and gastric cells.
    Neumeyer V; Grandl M; Dietl A; Brutau-Abia A; Allgäuer M; Kalali B; Zhang Y; Pan KF; Steiger K; Vieth M; Anton M; Mejías-Luque R; Gerhard M
    Carcinogenesis; 2019 Jun; 40(4):551-559. PubMed ID: 30380024
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Control of Wnt Receptor Turnover by R-spondin-ZNRF3/RNF43 Signaling Module and Its Dysregulation in Cancer.
    Hao HX; Jiang X; Cong F
    Cancers (Basel); 2016 Jun; 8(6):. PubMed ID: 27338477
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.