BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 33070193)

  • 1. Haploinsufficiency of Tmem43 in cardiac myocytes activates the DNA damage response pathway leading to a late-onset senescence-associated pro-fibrotic cardiomyopathy.
    Rouhi L; Cheedipudi SM; Chen SN; Fan S; Lombardi R; Chen X; Coarfa C; Robertson MJ; Gurha P; Marian AJ
    Cardiovasc Res; 2021 Sep; 117(11):2377-2394. PubMed ID: 33070193
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA Damage Response/TP53 Pathway Is Activated and Contributes to the Pathogenesis of Dilated Cardiomyopathy Associated With LMNA (Lamin A/C) Mutations.
    Chen SN; Lombardi R; Karmouch J; Tsai JY; Czernuszewicz G; Taylor MRG; Mestroni L; Coarfa C; Gurha P; Marian AJ
    Circ Res; 2019 Mar; 124(6):856-873. PubMed ID: 30696354
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Deletion of the
    Rouhi L; Auguste G; Zhou Q; Lombardi R; Olcum M; Pourebrahim K; Cheedipudi SM; Asghar S; Hong K; Robertson MJ; Coarfa C; Gurha P; Marian AJ
    J Cardiovasc Aging; 2022 Jul; 2(3):. PubMed ID: 35891706
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Exercise restores dysregulated gene expression in a mouse model of arrhythmogenic cardiomyopathy.
    Cheedipudi SM; Hu J; Fan S; Yuan P; Karmouch J; Czernuszewicz G; Robertson MJ; Coarfa C; Hong K; Yao Y; Campbell H; Wehrens X; Gurha P; Marian AJ
    Cardiovasc Res; 2020 May; 116(6):1199-1213. PubMed ID: 31350552
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Aberrant accumulation of TMEM43 accompanied by perturbed transmural gene expression in arrhythmogenic cardiomyopathy.
    Shinomiya H; Kato H; Kuramoto Y; Watanabe N; Tsuruda T; Arimura T; Miyashita Y; Miyasaka Y; Mashimo T; Takuwa A; Motooka D; Okuzaki D; Matsuoka K; Tsukamoto O; Hakui H; Yamada N; Lee JK; Kioka H; Kitakaze M; Takashima S; Sakata Y; Asano Y
    FASEB J; 2021 Nov; 35(11):e21994. PubMed ID: 34674311
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Single-Cell RNA Sequencing Uncovers Paracrine Functions of the Epicardial-Derived Cells in Arrhythmogenic Cardiomyopathy.
    Yuan P; Cheedipudi SM; Rouhi L; Fan S; Simon L; Zhao Z; Hong K; Gurha P; Marian AJ
    Circulation; 2021 Jun; 143(22):2169-2187. PubMed ID: 33726497
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pharmacological suppression of the WNT signaling pathway attenuates age-dependent expression of the phenotype in a mouse model of arrhythmogenic cardiomyopathy.
    Cheedipudi SM; Fan S; Rouhi L; Marian AJ
    J Cardiovasc Aging; 2021; 1(3):. PubMed ID: 34447973
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Heterozygous LmnadelK32 mice develop dilated cardiomyopathy through a combined pathomechanism of haploinsufficiency and peptide toxicity.
    Cattin ME; Bertrand AT; Schlossarek S; Le Bihan MC; Skov Jensen S; Neuber C; Crocini C; Maron S; Lainé J; Mougenot N; Varnous S; Fromes Y; Hansen A; Eschenhagen T; Decostre V; Carrier L; Bonne G
    Hum Mol Genet; 2013 Aug; 22(15):3152-64. PubMed ID: 23575224
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The EP300/TP53 pathway, a suppressor of the Hippo and canonical WNT pathways, is activated in human hearts with arrhythmogenic cardiomyopathy in the absence of overt heart failure.
    Rouhi L; Fan S; Cheedipudi SM; Braza-Boïls A; Molina MS; Yao Y; Robertson MJ; Coarfa C; Gimeno JR; Molina P; Gurha P; Zorio E; Marian AJ
    Cardiovasc Res; 2022 May; 118(6):1466-1478. PubMed ID: 34132777
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Genetic inactivation of β-catenin is salubrious, whereas its activation is deleterious in desmoplakin cardiomyopathy.
    Olcum M; Fan S; Rouhi L; Cheedipudi S; Cathcart B; Jeong HH; Zhao Z; Gurha P; Marian AJ
    Cardiovasc Res; 2023 Dec; 119(17):2712-2728. PubMed ID: 37625794
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Altered Expression of
    Zink M; Seewald A; Rohrbach M; Brodehl A; Liedtke D; Williams T; Childs SJ; Gerull B
    Int J Mol Sci; 2022 Aug; 23(17):. PubMed ID: 36076925
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Severe Cardiac Dysfunction and Death Caused by Arrhythmogenic Right Ventricular Cardiomyopathy Type 5 Are Improved by Inhibition of Glycogen Synthase Kinase-3β.
    Padrón-Barthe L; Villalba-Orero M; Gómez-Salinero JM; Domínguez F; Román M; Larrasa-Alonso J; Ortiz-Sánchez P; Martínez F; López-Olañeta M; Bonzón-Kulichenko E; Vázquez J; Martí-Gómez C; Santiago DJ; Prados B; Giovinazzo G; Gómez-Gaviro MV; Priori S; Garcia-Pavia P; Lara-Pezzi E
    Circulation; 2019 Oct; 140(14):1188-1204. PubMed ID: 31567019
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CTRP15 derived from cardiac myocytes attenuates TGFβ1-induced fibrotic response in cardiac fibroblasts.
    Zhao Q; Zhang CL; Xiang RL; Wu LL; Li L
    Cardiovasc Drugs Ther; 2020 Oct; 34(5):591-604. PubMed ID: 32424654
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genetic Ablation of the DNA Damage Response Pathway Attenuates Lamin-Associated Dilated Cardiomyopathy in Mice.
    Cheedipudi SM; Asghar S; Marian AJ
    JACC Basic Transl Sci; 2022 Dec; 7(12):1232-1245. PubMed ID: 36644279
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TMEM43-S358L mutation enhances NF-κB-TGFβ signal cascade in arrhythmogenic right ventricular dysplasia/cardiomyopathy.
    Zheng G; Jiang C; Li Y; Yang D; Ma Y; Zhang B; Li X; Zhang P; Hu X; Zhao X; Du J; Lin X
    Protein Cell; 2019 Feb; 10(2):104-119. PubMed ID: 29980933
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Loss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy.
    Henpita C; Vyas R; Healy CL; Kieu TL; Gurkar AU; Yousefzadeh MJ; Cui Y; Lu A; Angelini LA; O'Kelly RD; McGowan SJ; Chandrasekhar S; Vanderpool RR; Hennessy-Wack D; Ross MA; Bachman TN; McTiernan C; Pillai SPS; Ladiges W; Lavasani M; Huard J; Beer-Stolz D; St Croix CM; Watkins SC; Robbins PD; Mora AL; Kelley EE; Wang Y; O'Connell TD; Niedernhofer LJ
    Aging Cell; 2023 Apr; 22(4):e13782. PubMed ID: 36734200
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PANoptosis is a prominent feature of desmoplakin cardiomyopathy.
    Olcum M; Rouhi L; Fan S; Gonzales MM; Jeong HH; Zhao Z; Gurha P; Marian AJ
    J Cardiovasc Aging; 2023 Feb; 3(1):. PubMed ID: 36818425
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combined deficiency of dystrophin and beta1 integrin in the cardiac myocyte causes myocardial dysfunction, fibrosis and calcification.
    Elsherif L; Huang MS; Shai SY; Yang Y; Li RY; Chun J; Mekany MA; Chu AL; Kaufman SJ; Ross RS
    Circ Res; 2008 May; 102(9):1109-17. PubMed ID: 18340010
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Excess TGF-β1 Drives Cardiac Mesenchymal Stromal Cells to a Pro-Fibrotic Commitment in Arrhythmogenic Cardiomyopathy.
    Maione AS; Stadiotti I; Pilato CA; Perrucci GL; Saverio V; Catto V; Vettor G; Casella M; Guarino A; Polvani G; Pompilio G; Sommariva E
    Int J Mol Sci; 2021 Mar; 22(5):. PubMed ID: 33800912
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Therapeutic Modulation of the Immune Response in Arrhythmogenic Cardiomyopathy.
    Chelko SP; Asimaki A; Lowenthal J; Bueno-Beti C; Bedja D; Scalco A; Amat-Alarcon N; Andersen P; Judge DP; Tung L; Saffitz JE
    Circulation; 2019 Oct; 140(18):1491-1505. PubMed ID: 31533459
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.