These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

234 related articles for article (PubMed ID: 33070870)

  • 1. Loss of Fbxw7 triggers mammary tumorigenesis associated with E2F/c-Myc activation and Trp53 mutation.
    Meyer AE; Furumo Q; Stelloh C; Minella AC; Rao S
    Neoplasia; 2020 Nov; 22(11):644-658. PubMed ID: 33070870
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Recombinant human adenovirus-p53 injection induced apoptosis in hepatocellular carcinoma cell lines mediated by p53-Fbxw7 pathway, which controls c-Myc and cyclin E.
    Tu K; Zheng X; Zhou Z; Li C; Zhang J; Gao J; Yao Y; Liu Q
    PLoS One; 2013; 8(7):e68574. PubMed ID: 23840897
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MicroRNA-223 regulates cyclin E activity by modulating expression of F-box and WD-40 domain protein 7.
    Xu Y; Sengupta T; Kukreja L; Minella AC
    J Biol Chem; 2010 Nov; 285(45):34439-46. PubMed ID: 20826802
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation.
    Fujii Y; Yada M; Nishiyama M; Kamura T; Takahashi H; Tsunematsu R; Susaki E; Nakagawa T; Matsumoto A; Nakayama KI
    Cancer Sci; 2006 Aug; 97(8):729-36. PubMed ID: 16863506
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The FBXW7-NOTCH interactome: A ubiquitin proteasomal system-induced crosstalk modulating oncogenic transformation in human tissues.
    Kar R; Jha SK; Ojha S; Sharma A; Dholpuria S; Raju VSR; Prasher P; Chellappan DK; Gupta G; Kumar Singh S; Paudel KR; Hansbro PM; Kumar Singh S; Ruokolainen J; Kesari KK; Dua K; Jha NK
    Cancer Rep (Hoboken); 2021 Aug; 4(4):e1369. PubMed ID: 33822486
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loss of Fbxw7 Impairs Development of and Induces Heterogeneous Tumor Formation in the Mouse Mammary Gland.
    Onoyama I; Nakayama S; Shimizu H; Nakayama KI
    Cancer Res; 2020 Dec; 80(24):5515-5530. PubMed ID: 33234509
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis.
    Onoyama I; Tsunematsu R; Matsumoto A; Kimura T; de Alborán IM; Nakayama K; Nakayama KI
    J Exp Med; 2007 Nov; 204(12):2875-88. PubMed ID: 17984302
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Loss of Fbxw7 synergizes with activated Akt signaling to promote c-Myc dependent cholangiocarcinogenesis.
    Wang J; Wang H; Peters M; Ding N; Ribback S; Utpatel K; Cigliano A; Dombrowski F; Xu M; Chen X; Song X; Che L; Evert M; Cossu A; Gordan J; Zeng Y; Chen X; Calvisi DF
    J Hepatol; 2019 Oct; 71(4):742-752. PubMed ID: 31195063
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Loss of CDC4/FBXW7 in gastric carcinoma.
    Milne AN; Leguit R; Corver WE; Morsink FH; Polak M; de Leng WW; Carvalho R; Offerhaus GJ
    Cell Oncol; 2010; 32(5-6):347-59. PubMed ID: 20448329
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Skp1-Cullin-F-box (SCF)-type ubiquitin ligase FBXW7 negatively regulates spermatogonial stem cell self-renewal.
    Kanatsu-Shinohara M; Onoyama I; Nakayama KI; Shinohara T
    Proc Natl Acad Sci U S A; 2014 Jun; 111(24):8826-31. PubMed ID: 24879440
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SCF(FBXW7)-mediated degradation of p53 promotes cell recovery after UV-induced DNA damage.
    Galindo-Moreno M; Giráldez S; Limón-Mortés MC; Belmonte-Fernández A; Reed SI; Sáez C; Japón MÁ; Tortolero M; Romero F
    FASEB J; 2019 Oct; 33(10):11420-11430. PubMed ID: 31337255
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MYC is a critical target of FBXW7.
    Sato M; Rodriguez-Barrueco R; Yu J; Do C; Silva JM; Gautier J
    Oncotarget; 2015 Feb; 6(5):3292-305. PubMed ID: 25669969
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations.
    Thirimanne HN; Wu F; Janssens DH; Swanger J; Diab A; Feldman HM; Amezquita RA; Gottardo R; Paddison PJ; Henikoff S; Clurman BE
    Elife; 2022 Feb; 11():. PubMed ID: 35225231
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Recent insight into the role of FBXW7 as a tumor suppressor.
    Yumimoto K; Nakayama KI
    Semin Cancer Biol; 2020 Dec; 67(Pt 2):1-15. PubMed ID: 32113998
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Opposing functions of Fbxw7 in keratinocyte growth, differentiation and skin tumorigenesis mediated through negative regulation of c-Myc and Notch.
    Ishikawa Y; Hosogane M; Okuyama R; Aoyama S; Onoyama I; Nakayama KI; Nakayama K
    Oncogene; 2013 Apr; 32(15):1921-32. PubMed ID: 22665065
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Loss of FBXW7-mediated degradation of BRAF elicits resistance to BET inhibitors in adult T cell leukemia cells.
    Yeh CH; Bellon M; Wang F; Zhang H; Fu L; Nicot C
    Mol Cancer; 2020 Sep; 19(1):139. PubMed ID: 32907612
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fbxw7 haploinsufficiency loses its protection against DNA damage and accelerates MNU-induced gastric carcinogenesis.
    Jiang Y; Qi X; Liu X; Zhang J; Ji J; Zhu Z; Ren J; Yu Y
    Oncotarget; 2017 May; 8(20):33444-33456. PubMed ID: 28422719
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MYC, FBXW7 and TP53 copy number variation and expression in gastric cancer.
    Calcagno DQ; Freitas VM; Leal MF; de Souza CR; Demachki S; Montenegro R; Assumpção PP; Khayat AS; Smith Mde A; dos Santos AK; Burbano RR
    BMC Gastroenterol; 2013 Sep; 13():141. PubMed ID: 24053468
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The HTLV-I oncoprotein Tax inactivates the tumor suppressor FBXW7.
    Bellon M; Yeh C-h; Bai XT; Nicot C
    J Virol; 2024 Jul; 98(7):e0040524. PubMed ID: 38874362
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Tumor Suppressor FBW7 and the Vitamin D Receptor Are Mutual Cofactors in Protein Turnover and Transcriptional Regulation.
    Salehi-Tabar R; Memari B; Wong H; Dimitrov V; Rochel N; White JH
    Mol Cancer Res; 2019 Mar; 17(3):709-719. PubMed ID: 30606768
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.