BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 33077645)

  • 1. V Region of IgG Controls the Molecular Properties of the Binding Site for Neonatal Fc Receptor.
    Rossini S; Noé R; Daventure V; Lecerf M; Justesen S; Dimitrov JD
    J Immunol; 2020 Nov; 205(10):2850-2860. PubMed ID: 33077645
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Conformational Destabilization of Immunoglobulin G Increases the Low pH Binding Affinity with the Neonatal Fc Receptor.
    Walters BT; Jensen PF; Larraillet V; Lin K; Patapoff T; Schlothauer T; Rand KD; Zhang J
    J Biol Chem; 2016 Jan; 291(4):1817-1825. PubMed ID: 26627822
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A Two-pronged Binding Mechanism of IgG to the Neonatal Fc Receptor Controls Complex Stability and IgG Serum Half-life.
    Jensen PF; Schoch A; Larraillet V; Hilger M; Schlothauer T; Emrich T; Rand KD
    Mol Cell Proteomics; 2017 Mar; 16(3):451-456. PubMed ID: 28062799
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Changes in complementarity-determining regions significantly alter IgG binding to the neonatal Fc receptor (FcRn) and pharmacokinetics.
    Piche-Nicholas NM; Avery LB; King AC; Kavosi M; Wang M; O'Hara DM; Tchistiakova L; Katragadda M
    MAbs; 2018 Jan; 10(1):81-94. PubMed ID: 28991504
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Analysis of the pH dependence of the neonatal Fc receptor/immunoglobulin G interaction using antibody and receptor variants.
    Raghavan M; Bonagura VR; Morrison SL; Bjorkman PJ
    Biochemistry; 1995 Nov; 34(45):14649-57. PubMed ID: 7578107
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of the interactions of rabbit neonatal Fc receptor (FcRn) with rabbit and human IgG isotypes.
    Szikora B; Hiripi L; Bender B; Kacskovics I; Iliás A
    PLoS One; 2017; 12(9):e0185662. PubMed ID: 28957416
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Investigating the interaction between the neonatal Fc receptor and monoclonal antibody variants by hydrogen/deuterium exchange mass spectrometry.
    Jensen PF; Larraillet V; Schlothauer T; Kettenberger H; Hilger M; Rand KD
    Mol Cell Proteomics; 2015 Jan; 14(1):148-61. PubMed ID: 25378534
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Monoclonal antibodies with identical Fc sequences can bind to FcRn differentially with pharmacokinetic consequences.
    Wang W; Lu P; Fang Y; Hamuro L; Pittman T; Carr B; Hochman J; Prueksaritanont T
    Drug Metab Dispos; 2011 Sep; 39(9):1469-77. PubMed ID: 21610128
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insight into the avidity-affinity relationship of the bivalent, pH-dependent interaction between IgG and FcRn.
    Reusch J; Andersen JT; Rant U; Schlothauer T
    MAbs; 2024; 16(1):2361585. PubMed ID: 38849969
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Qualification of a homogeneous cell-based neonatal Fc receptor (FcRn) binding assay and its application to studies on Fc functionality of IgG-based therapeutics.
    Mathur A; Arora T; Liu L; Crouse-Zeineddini J; Mukku V
    J Immunol Methods; 2013 Apr; 390(1-2):81-91. PubMed ID: 23384837
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human IgG lacking effector functions demonstrate lower FcRn-binding and reduced transplacental transport.
    Stapleton NM; Armstrong-Fisher SS; Andersen JT; van der Schoot CE; Porter C; Page KR; Falconer D; de Haas M; Williamson LM; Clark MR; Vidarsson G; Armour KL
    Mol Immunol; 2018 Mar; 95():1-9. PubMed ID: 29367080
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antigen physiochemical properties allosterically effect the IgG Fc-region and Fc neonatal receptor affinity.
    Sun Y; Estevez A; Schlothauer T; Wecksler AT
    MAbs; 2020; 12(1):1802135. PubMed ID: 32795110
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Are endosomal trafficking parameters better targets for improving mAb pharmacokinetics than FcRn binding affinity?
    Gurbaxani B; Dostalek M; Gardner I
    Mol Immunol; 2013 Dec; 56(4):660-74. PubMed ID: 23917469
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity.
    Abdiche YN; Yeung YA; Chaparro-Riggers J; Barman I; Strop P; Chin SM; Pham A; Bolton G; McDonough D; Lindquist K; Pons J; Rajpal A
    MAbs; 2015; 7(2):331-43. PubMed ID: 25658443
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Crystal structure and immunoglobulin G binding properties of the human major histocompatibility complex-related Fc receptor(,).
    West AP; Bjorkman PJ
    Biochemistry; 2000 Aug; 39(32):9698-708. PubMed ID: 10933786
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enhanced FcRn-dependent transepithelial delivery of IgG by Fc-engineering and polymerization.
    Foss S; Grevys A; Sand KMK; Bern M; Blundell P; Michaelsen TE; Pleass RJ; Sandlie I; Andersen JT
    J Control Release; 2016 Feb; 223():42-52. PubMed ID: 26718855
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Charge-mediated influence of the antibody variable domain on FcRn-dependent pharmacokinetics.
    Schoch A; Kettenberger H; Mundigl O; Winter G; Engert J; Heinrich J; Emrich T
    Proc Natl Acad Sci U S A; 2015 May; 112(19):5997-6002. PubMed ID: 25918417
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Impact of IgG2 high molecular weight species on neonatal Fc receptor binding assays.
    Zhang Y; Mathur A; Maher G; Arroll T; Bailey R
    Anal Biochem; 2015 Nov; 489():25-31. PubMed ID: 26255698
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Properties of human IgG1s engineered for enhanced binding to the neonatal Fc receptor (FcRn).
    Dall'Acqua WF; Kiener PA; Wu H
    J Biol Chem; 2006 Aug; 281(33):23514-24. PubMed ID: 16793771
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Combined glyco- and protein-Fc engineering simultaneously enhance cytotoxicity and half-life of a therapeutic antibody.
    Monnet C; Jorieux S; Souyris N; Zaki O; Jacquet A; Fournier N; Crozet F; de Romeuf C; Bouayadi K; Urbain R; Behrens CK; Mondon P; Fontayne A
    MAbs; 2014; 6(2):422-36. PubMed ID: 24492301
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.