BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

610 related articles for article (PubMed ID: 33078877)

  • 1. Synthesis, antimicrobial evaluation, DNA gyrase inhibition, and in silico pharmacokinetic studies of novel quinoline derivatives.
    El-Shershaby MH; El-Gamal KM; Bayoumi AH; El-Adl K; Ahmed HEA; Abulkhair HS
    Arch Pharm (Weinheim); 2021 Feb; 354(2):e2000277. PubMed ID: 33078877
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular docking, discovery, synthesis, and pharmacological properties of new 6-substituted-2-(3-phenoxyphenyl)-4-phenyl quinoline derivatives; an approach to developing potent DNA gyrase inhibitors/antibacterial agents.
    Alagumuthu M; Arumugam S
    Bioorg Med Chem; 2017 Feb; 25(4):1448-1455. PubMed ID: 28094220
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antimicrobial evaluation of thiadiazino and thiazolo quinoxaline hybrids as potential DNA gyrase inhibitors; design, synthesis, characterization and morphological studies.
    Ammar YA; Farag AA; Ali AM; Hessein SA; Askar AA; Fayed EA; Elsisi DM; Ragab A
    Bioorg Chem; 2020 Jun; 99():103841. PubMed ID: 32325335
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel 1,2,4-oxadiazole-chalcone/oxime hybrids as potential antibacterial DNA gyrase inhibitors: Design, synthesis, ADMET prediction and molecular docking study.
    Ibrahim TS; Almalki AJ; Moustafa AH; Allam RM; Abuo-Rahma GEA; El Subbagh HI; Mohamed MFA
    Bioorg Chem; 2021 Jun; 111():104885. PubMed ID: 33838559
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeted potent antimicrobial benzochromene-based analogues: Synthesis, computational studies, and inhibitory effect against 14α-Demethylase and DNA Gyrase.
    Fouda AM; Hassan AH; Eliwa EM; Ahmed HEA; Al-Dies AM; Omar AM; Nassar HS; Halawa AH; Aljuhani N; El-Agrody AM
    Bioorg Chem; 2020 Dec; 105():104387. PubMed ID: 33130344
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, and antibacterial evaluation of new quinoline-1,3,4-oxadiazole and quinoline-1,2,4-triazole hybrids as potential inhibitors of DNA gyrase and topoisomerase IV.
    Hofny HA; Mohamed MFA; Gomaa HAM; Abdel-Aziz SA; Youssif BGM; El-Koussi NA; Aboraia AS
    Bioorg Chem; 2021 Jul; 112():104920. PubMed ID: 33910078
    [TBL] [Abstract][Full Text] [Related]  

  • 7. One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor.
    Salem MA; Ragab A; Askar AA; El-Khalafawy A; Makhlouf AH
    Eur J Med Chem; 2020 Feb; 188():111977. PubMed ID: 31927313
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antimicrobial Activity of New 2-Thioxo-benzo[g]quinazolin-4(3H)-one Derivatives.
    Al-Salahi R; Abuelizz HA; Dib RE; Marzouk M; Alshammari MB
    Med Chem; 2016; 13(1):85-92. PubMed ID: 27306606
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, and antibacterial activity of novel 4,5-dihydro-1H-pyrazole derivatives as DNA gyrase inhibitors.
    Liu JJ; Sun J; Fang YB; Yang YA; Jiao RH; Zhu HL
    Org Biomol Chem; 2014 Feb; 12(6):998-1008. PubMed ID: 24382549
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development and radiosterilization of new hydrazono-quinoline hybrids as DNA gyrase and topoisomerase IV inhibitors: Antimicrobial and hemolytic activities against uropathogenic isolates with molecular docking study.
    Ammar YA; Micky JA; Aboul-Magd DS; Abd El-Hafez SMA; Hessein SA; Ali AM; Ragab A
    Chem Biol Drug Des; 2023 Feb; 101(2):245-270. PubMed ID: 36305722
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of New Schiff Bases Tethered Pyrazole Moiety: Design, Synthesis, Biological Evaluation, and Molecular Docking Study as Dual Targeting DHFR/DNA Gyrase Inhibitors with Immunomodulatory Activity.
    Hassan AS; Askar AA; Naglah AM; Almehizia AA; Ragab A
    Molecules; 2020 Jun; 25(11):. PubMed ID: 32498469
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, Antimicrobial Activity and Molecular Docking of Novel Thiourea Derivatives Tagged with Thiadiazole, Imidazole and Triazine Moieties as Potential DNA Gyrase and Topoisomerase IV Inhibitors.
    Hashem HE; Amr AEE; Nossier ES; Elsayed EA; Azmy EM
    Molecules; 2020 Jun; 25(12):. PubMed ID: 32549386
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design of (quinolin-4-ylthio)carboxylic acids as new Escherichia coli DNA gyrase B inhibitors: machine learning studies, molecular docking, synthesis and biological testing.
    Metelytsia L; Hodyna D; Dobrodub I; Semenyuta I; Zavhorodnii M; Blagodatny V; Kovalishyn V; Brazhko O
    Comput Biol Chem; 2020 Apr; 85():107224. PubMed ID: 32018168
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of novel 2-aminobenzothiazole derivatives as potential antimicrobial agents with dual DNA gyrase/topoisomerase IV inhibition.
    Ismail MMF; Abdulwahab HG; Nossier ES; El Menofy NG; Abdelkhalek BA
    Bioorg Chem; 2020 Jan; 94():103437. PubMed ID: 31812260
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis and molecular modeling studies of new series of s-triazine derivatives as antimicrobial agents against multi-drug resistant clinical isolates.
    Haiba NS; Khalil HH; Moniem MA; El-Wakil MH; Bekhit AA; Khattab SN
    Bioorg Chem; 2019 Aug; 89():103013. PubMed ID: 31174040
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis, antimicrobial activity and molecular docking studies of some novel di-substituted sulfonylquinoxaline derivatives.
    Ammar YA; Farag AA; Ali AM; Ragab A; Askar AA; Elsisi DM; Belal A
    Bioorg Chem; 2020 Nov; 104():104164. PubMed ID: 32896807
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Potent antibacterial activity of dihydydropyrimidine-1,3,5-triazines via inhibition of DNA gyrase and antifungal activity with favourable metabolic profile.
    Masih A; Shrivastava JK; Bhat HR; Singh UP
    Chem Biol Drug Des; 2020 Aug; 96(2):861-869. PubMed ID: 32333828
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design and synthesis of some novel hybrid molecules based on 4-thiazolidinone bearing pyridine-pyrazole scaffolds: molecular docking and molecular dynamics simulations of its major constituent onto DNA gyrase inhibition.
    Desai NC; Jadeja DJ; Jethawa AM; Ahmad I; Patel H; Dave BP
    Mol Divers; 2024 Apr; 28(2):693-709. PubMed ID: 36750538
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro evaluation of new 2-phenoxy-benzo[g][1,2,4]triazolo[1,5-a]quinazoline derivatives as antimicrobial agents.
    Abuelizz HA; El-Dib RA; Marzouk M; Al-Salahi R
    Microb Pathog; 2018 Apr; 117():60-67. PubMed ID: 29432912
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New Caffeic Acid Derivatives as Antimicrobial Agents: Design, Synthesis, Evaluation and Docking.
    Merlani M; Barbakadze V; Amiranashvili L; Gogilashvili L; Poroikov V; Petrou A; Geronikaki A; Ciric A; Glamoclija J; Sokovic M
    Curr Top Med Chem; 2019; 19(4):292-304. PubMed ID: 30674263
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 31.