470 related articles for article (PubMed ID: 33079262)
1. Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer's disease models and human brains.
Vaillant-Beuchot L; Mary A; Pardossi-Piquard R; Bourgeois A; Lauritzen I; Eysert F; Kinoshita PF; Cazareth J; Badot C; Fragaki K; Bussiere R; Martin C; Mary R; Bauer C; Pagnotta S; Paquis-Flucklinger V; Buée-Scherrer V; Buée L; Lacas-Gervais S; Checler F; Chami M
Acta Neuropathol; 2021 Jan; 141(1):39-65. PubMed ID: 33079262
[TBL] [Abstract][Full Text] [Related]
2. The amyloid precursor protein and its derived fragments concomitantly contribute to the alterations of mitochondrial transport machinery in Alzheimer's disease.
Vaillant-Beuchot L; Eysert F; Duval B; Kinoshita PF; Pardossi-Piquard R; Bauer C; Eddarkaoui S; Buée L; Checler F; Chami M
Cell Death Dis; 2024 May; 15(5):367. PubMed ID: 38806484
[TBL] [Abstract][Full Text] [Related]
3. Mitochondrial dysfunction and accumulation of the β-secretase-cleaved C-terminal fragment of APP in Alzheimer's disease transgenic mice.
Devi L; Ohno M
Neurobiol Dis; 2012 Jan; 45(1):417-24. PubMed ID: 21933711
[TBL] [Abstract][Full Text] [Related]
4. Accumulation of APP-CTF induces mitophagy dysfunction in the iNSCs model of Alzheimer's disease.
Lee SE; Kwon D; Shin N; Kong D; Kim NG; Kim HY; Kim MJ; Choi SW; Kang KS
Cell Death Discov; 2022 Jan; 8(1):1. PubMed ID: 35013145
[TBL] [Abstract][Full Text] [Related]
5. η-Secretase processing of APP inhibits neuronal activity in the hippocampus.
Willem M; Tahirovic S; Busche MA; Ovsepian SV; Chafai M; Kootar S; Hornburg D; Evans LD; Moore S; Daria A; Hampel H; Müller V; Giudici C; Nuscher B; Wenninger-Weinzierl A; Kremmer E; Heneka MT; Thal DR; Giedraitis V; Lannfelt L; Müller U; Livesey FJ; Meissner F; Herms J; Konnerth A; Marie H; Haass C
Nature; 2015 Oct; 526(7573):443-7. PubMed ID: 26322584
[TBL] [Abstract][Full Text] [Related]
6. Mitochondria are devoid of amyloid β-protein (Aβ)-producing secretases: Evidence for unlikely occurrence within mitochondria of Aβ generation from amyloid precursor protein.
Mamada N; Tanokashira D; Ishii K; Tamaoka A; Araki W
Biochem Biophys Res Commun; 2017 Apr; 486(2):321-328. PubMed ID: 28302486
[TBL] [Abstract][Full Text] [Related]
7. Targeting γ-secretase triggers the selective enrichment of oligomeric APP-CTFs in brain extracellular vesicles from Alzheimer cell and mouse models.
Lauritzen I; Bécot A; Bourgeois A; Pardossi-Piquard R; Biferi MG; Barkats M; Checler F
Transl Neurodegener; 2019; 8():35. PubMed ID: 31827783
[TBL] [Abstract][Full Text] [Related]
8. Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer's disease mutations but not by inhibition of BACE1.
Johnson ECB; Ho K; Yu GQ; Das M; Sanchez PE; Djukic B; Lopez I; Yu X; Gill M; Zhang W; Paz JT; Palop JJ; Mucke L
Mol Neurodegener; 2020 Sep; 15(1):53. PubMed ID: 32921309
[TBL] [Abstract][Full Text] [Related]
9. Phosphorylation of amyloid precursor carboxy-terminal fragments enhances their processing by a gamma-secretase-dependent mechanism.
Vingtdeux V; Hamdane M; Gompel M; Bégard S; Drobecq H; Ghestem A; Grosjean ME; Kostanjevecki V; Grognet P; Vanmechelen E; Buée L; Delacourte A; Sergeant N
Neurobiol Dis; 2005 Nov; 20(2):625-37. PubMed ID: 15936948
[TBL] [Abstract][Full Text] [Related]
10. Measuring APP carboxy-terminal fragments.
Esposito LA
Methods Mol Biol; 2011; 670():71-84. PubMed ID: 20967584
[TBL] [Abstract][Full Text] [Related]
11. Alzheimer's disease.
De-Paula VJ; Radanovic M; Diniz BS; Forlenza OV
Subcell Biochem; 2012; 65():329-52. PubMed ID: 23225010
[TBL] [Abstract][Full Text] [Related]
12. Does Intraneuronal Accumulation of Carboxyl-terminal Fragments of the Amyloid Precursor Protein Trigger Early Neurotoxicity in Alzheimer's Disease?
Lauritzen I; Pardossi-Piquard R; Bourgeois A; Bécot A; Checler F
Curr Alzheimer Res; 2019; 16(5):453-457. PubMed ID: 30907322
[TBL] [Abstract][Full Text] [Related]
13. Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer's disease.
Roca-Agujetas V; Barbero-Camps E; de Dios C; Podlesniy P; Abadin X; Morales A; Marí M; Trullàs R; Colell A
Mol Neurodegener; 2021 Mar; 16(1):15. PubMed ID: 33685483
[TBL] [Abstract][Full Text] [Related]
14. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
[TBL] [Abstract][Full Text] [Related]
15. Study of mitophagy and ATP-related metabolomics based on β-amyloid levels in Alzheimer's disease.
Xiong X; Li S; Han TL; Zhou F; Zhang X; Tian M; Tang L; Li Y
Exp Cell Res; 2020 Nov; 396(1):112266. PubMed ID: 32905804
[TBL] [Abstract][Full Text] [Related]
16. ErbB2 regulates autophagic flux to modulate the proteostasis of APP-CTFs in Alzheimer's disease.
Wang BJ; Her GM; Hu MK; Chen YW; Tung YT; Wu PY; Hsu WM; Lee H; Jin LW; Hwang SL; Chen RP; Huang CJ; Liao YF
Proc Natl Acad Sci U S A; 2017 Apr; 114(15):E3129-E3138. PubMed ID: 28351972
[TBL] [Abstract][Full Text] [Related]
17. Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence.
Kimura A; Hata S; Suzuki T
J Biol Chem; 2016 Nov; 291(46):24041-24053. PubMed ID: 27687728
[TBL] [Abstract][Full Text] [Related]
18. A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ.
Kwart D; Gregg A; Scheckel C; Murphy EA; Paquet D; Duffield M; Fak J; Olsen O; Darnell RB; Tessier-Lavigne M
Neuron; 2019 Oct; 104(2):256-270.e5. PubMed ID: 31416668
[TBL] [Abstract][Full Text] [Related]
19. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
[TBL] [Abstract][Full Text] [Related]
20. MT5-MMP controls APP and β-CTF/C99 metabolism through proteolytic-dependent and -independent mechanisms relevant for Alzheimer's disease.
García-González L; Paumier JM; Louis L; Pilat D; Bernard A; Stephan D; Jullien N; Checler F; Nivet E; Khrestchatisky M; Baranger K; Rivera S
FASEB J; 2021 Jul; 35(7):e21727. PubMed ID: 34117802
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
