BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 33080222)

  • 1. Coupled membrane lipid miscibility and phosphotyrosine-driven protein condensation phase transitions.
    Chung JK; Huang WYC; Carbone CB; Nocka LM; Parikh AN; Vale RD; Groves JT
    Biophys J; 2021 Apr; 120(7):1257-1265. PubMed ID: 33080222
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS.
    Huang WY; Yan Q; Lin WC; Chung JK; Hansen SD; Christensen SM; Tu HL; Kuriyan J; Groves JT
    Proc Natl Acad Sci U S A; 2016 Jul; 113(29):8218-23. PubMed ID: 27370798
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS.
    Huang WYC; Alvarez S; Kondo Y; Lee YK; Chung JK; Lam HYM; Biswas KH; Kuriyan J; Groves JT
    Science; 2019 Mar; 363(6431):1098-1103. PubMed ID: 30846600
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A two-component protein condensate of the EGFR cytoplasmic tail and Grb2 regulates Ras activation by SOS at the membrane.
    Lin CW; Nocka LM; Stinger BL; DeGrandchamp JB; Lew LJN; Alvarez S; Phan HT; Kondo Y; Kuriyan J; Groves JT
    Proc Natl Acad Sci U S A; 2022 May; 119(19):e2122531119. PubMed ID: 35507881
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ZAP-70 is essential for the T cell antigen receptor-induced plasma membrane targeting of SOS and Vav in T cells.
    Salojin KV; Zhang J; Meagher C; Delovitch TL
    J Biol Chem; 2000 Feb; 275(8):5966-75. PubMed ID: 10681590
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A complex of Grb2 adaptor protein, Sos exchange factor, and a 36-kDa membrane-bound tyrosine phosphoprotein is implicated in ras activation in T cells.
    Buday L; Egan SE; Rodriguez Viciana P; Cantrell DA; Downward J
    J Biol Chem; 1994 Mar; 269(12):9019-23. PubMed ID: 7510700
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Epidermal growth factor receptor targeting prevents uncoupling of the Grb2-SOS complex.
    Holt KH; Waters SB; Okada S; Yamauchi K; Decker SJ; Saltiel AR; Motto DG; Koretzky GA; Pessin JE
    J Biol Chem; 1996 Apr; 271(14):8300-6. PubMed ID: 8626525
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SH3 domains of the adapter molecule Grb2 complex with two proteins in T cells: the guanine nucleotide exchange protein Sos and a 75-kDa protein that is a substrate for T cell antigen receptor-activated tyrosine kinases.
    Reif K; Buday L; Downward J; Cantrell DA
    J Biol Chem; 1994 May; 269(19):14081-7. PubMed ID: 8188688
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Independent binding of peptide ligands to the SH2 and SH3 domains of Grb2.
    Lemmon MA; Ladbury JE; Mandiyan V; Zhou M; Schlessinger J
    J Biol Chem; 1994 Dec; 269(50):31653-8. PubMed ID: 7527391
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dynamic Scaling Analysis of Molecular Motion within the LAT:Grb2:SOS Protein Network on Membranes.
    Huang WYC; Chiang HK; Groves JT
    Biophys J; 2017 Oct; 113(8):1807-1813. PubMed ID: 29045874
    [TBL] [Abstract][Full Text] [Related]  

  • 11. High affinity IgG receptor activation of Src family kinases is required for modulation of the Shc-Grb2-Sos complex and the downstream activation of the nicotinamide adenine dinucleotide phosphate (reduced) oxidase.
    Park RK; Erdreich-Epstein A; Liu M; Izadi KD; Durden DL
    J Immunol; 1999 Dec; 163(11):6023-34. PubMed ID: 10570290
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insulin and epidermal growth factor receptors regulate distinct pools of Grb2-SOS in the control of Ras activation.
    Waters SB; Chen D; Kao AW; Okada S; Holt KH; Pessin JE
    J Biol Chem; 1996 Jul; 271(30):18224-30. PubMed ID: 8663461
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel recruitment of Shc, Grb2, and Sos by fibroblast growth factor receptor-1 in v-Src-transformed cells.
    Curto M; Frankel P; Carrero A; Foster DA
    Biochem Biophys Res Commun; 1998 Feb; 243(2):555-60. PubMed ID: 9480847
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Gastrin induces tyrosine phosphorylation of Shc proteins and their association with the Grb2/Sos complex.
    Seva C; Kowalski-Chauvel A; Blanchet JS; Vaysse N; Pradayrol L
    FEBS Lett; 1996 Jan; 378(1):74-8. PubMed ID: 8549807
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Signal transduction pathway of human fibroblast growth factor receptor 3. Identification of a novel 66-kDa phosphoprotein.
    Kanai M; Göke M; Tsunekawa S; Podolsky DK
    J Biol Chem; 1997 Mar; 272(10):6621-8. PubMed ID: 9045692
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Carbachol activates ERK2 in isolated gastric parietal cells via multiple signaling pathways.
    Takeuchi Y; Pausawasdi N; Todisco A
    Am J Physiol; 1999 Jun; 276(6):G1484-92. PubMed ID: 10362652
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Association of Shc, Cbl, Grb2, and Sos following treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin in primary rat hepatocytes.
    Park R; Kim DH; Kim MS; So HS; Chung HT; Kwon KB; Ryu DG; Kim BR
    Biochem Biophys Res Commun; 1998 Dec; 253(3):577-81. PubMed ID: 9918770
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Grb2 adaptor.
    Chardin P; Cussac D; Maignan S; Ducruix A
    FEBS Lett; 1995 Aug; 369(1):47-51. PubMed ID: 7641883
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Shc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes.
    Harmer SL; DeFranco AL
    Mol Cell Biol; 1997 Jul; 17(7):4087-95. PubMed ID: 9199344
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1.
    Rozakis-Adcock M; Fernley R; Wade J; Pawson T; Bowtell D
    Nature; 1993 May; 363(6424):83-5. PubMed ID: 8479540
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.