BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 33085454)

  • 1. Renal Handling of
    Uehara T; Kanazawa N; Suzuki C; Mizuno Y; Suzuki H; Hanaoka H; Arano Y
    Bioconjug Chem; 2020 Nov; 31(11):2618-2627. PubMed ID: 33085454
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Preferential Cleavage of a Tripeptide Linkage by Enzymes on Renal Brush Border Membrane To Reduce Renal Radioactivity Levels of Radiolabeled Antibody Fragments.
    Suzuki C; Uehara T; Kanazawa N; Wada S; Suzuki H; Arano Y
    J Med Chem; 2018 Jun; 61(12):5257-5268. PubMed ID: 29869881
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, and evaluation of [188Re]organorhenium-labeled antibody fragments with renal enzyme-cleavable linkage for low renal radioactivity levels.
    Uehara T; Koike M; Nakata H; Hanaoka H; Iida Y; Hashimoto K; Akizawa H; Endo K; Arano Y
    Bioconjug Chem; 2007; 18(1):190-8. PubMed ID: 17226973
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Renal brush border enzyme-cleavable linkages for low renal radioactivity levels of radiolabeled antibody fragments.
    Akizawa H; Imajima M; Hanaoka H; Uehara T; Satake S; Arano Y
    Bioconjug Chem; 2013 Feb; 24(2):291-9. PubMed ID: 23330714
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Gallium-67/68-Labeled Antibody Fragment for Immuno-SPECT/PET Shows Low Renal Radioactivity Without Loss of Tumor Uptake.
    Uehara T; Yokoyama M; Suzuki H; Hanaoka H; Arano Y
    Clin Cancer Res; 2018 Jul; 24(14):3309-3316. PubMed ID: 29666303
    [No Abstract]   [Full Text] [Related]  

  • 6. Renal metabolism of 3'-iodohippuryl N(epsilon)-maleoyl-L-lysine (HML)-conjugated Fab fragments.
    Fujioka Y; Arano Y; Ono M; Uehara T; Ogawa K; Namba S; Saga T; Nakamoto Y; Mukai T; Konishi J; Saji H
    Bioconjug Chem; 2001; 12(2):178-85. PubMed ID: 11312678
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reduction of the Renal Radioactivity of
    Suzuki H; Araki M; Tatsugi K; Ichinohe K; Uehara T; Arano Y
    J Med Chem; 2023 Jul; 66(13):8600-8613. PubMed ID: 37322876
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vitro system to estimate renal brush border enzyme-mediated cleavage of Peptide linkages for designing radiolabeled antibody fragments of low renal radioactivity levels.
    Fujioka Y; Satake S; Uehara T; Mukai T; Akizawa H; Ogawa K; Saji H; Endo K; Arano Y
    Bioconjug Chem; 2005; 16(6):1610-6. PubMed ID: 16287261
    [TBL] [Abstract][Full Text] [Related]  

  • 9. (67/68)Ga-labeling agent that liberates (67/68)Ga-NOTA-methionine by lysosomal proteolysis of parental low molecular weight polypeptides to reduce renal radioactivity levels.
    Uehara T; Rokugawa T; Kinoshita M; Nemoto S; Fransisco Lazaro GG; Hanaoka H; Arano Y
    Bioconjug Chem; 2014 Nov; 25(11):2038-45. PubMed ID: 25303645
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Chemical design of radiolabeled antibody fragments for low renal radioactivity levels.
    Arano Y; Fujioka Y; Akizawa H; Ono M; Uehara T; Wakisaka K; Nakayama M; Sakahara H; Konishi J; Saji H
    Cancer Res; 1999 Jan; 59(1):128-34. PubMed ID: 9892197
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Improved renal clearance and tumor targeting of 99mTc-labeled anti-Tac monoclonal antibody Fab by chemical modifications.
    Kim MK; Jeong HJ; Kao CH; Yao Z; Paik DS; Pie JE; Kobayashi H; Waldmann TA; Carrasquillo JA; Paik CH
    Nucl Med Biol; 2002 Feb; 29(2):139-46. PubMed ID: 11823118
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Preclinical Evaluation of
    Shi D; Fu W; Tan H; Lin Q; Shi H; Cheng D
    Mol Pharm; 2024 Jan; 21(1):303-312. PubMed ID: 38109713
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Renal brush border strategy: A developing procedure to reduce renal radioactivity levels of radiolabeled polypeptides.
    Arano Y
    Nucl Med Biol; 2021 Jan; 92():149-155. PubMed ID: 32169305
    [TBL] [Abstract][Full Text] [Related]  

  • 14. (99m)Tc-HYNIC-derivatized ternary ligand complexes for (99m)Tc-labeled polypeptides with low in vivo protein binding.
    Ono M; Arano Y; Mukai T; Fujioka Y; Ogawa K; Uehara T; Saga T; Konishi J; Saji H
    Nucl Med Biol; 2001 Apr; 28(3):215-24. PubMed ID: 11323230
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Plasma protein binding of (99m)Tc-labeled hydrazino nicotinamide derivatized polypeptides and peptides.
    Ono M; Arano Y; Mukai T; Uehara T; Fujioka Y; Ogawa K; Namba S; Nakayama M; Saga T; Konishi J; Horiuchi K; Yokoyama A; Saji H
    Nucl Med Biol; 2001 Feb; 28(2):155-64. PubMed ID: 11295426
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Strategies to reduce renal radioactivity levels of antibody fragments.
    Arano Y
    Q J Nucl Med; 1998 Dec; 42(4):262-70. PubMed ID: 9973841
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Design of radiolabeled antibody fragments for tumor-selective radioactivity localization--brush border enzyme-sensitive bond to decrease renal accumulation of radioactivity].
    Mukai T; Fujioka Y; Arano Y; Saji H
    Yakugaku Zasshi; 2003 Aug; 123(8):647-52. PubMed ID: 12931660
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and biological evaluation of the four isomers of technetium-99m labeled ethylenecysteamine cysteine ((99m)Tc-ECC), the mono-acid derivative of (99m)tc-L,L-ethylenedicysteine.
    Vanbilloen HP; Cleynhens BJ; Verbruggen AM
    Nucl Med Biol; 2000 Feb; 27(2):207-14. PubMed ID: 10773551
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dynamic and static small-animal SPECT in rats for monitoring renal function after 177Lu-labeled Tyr3-octreotate radionuclide therapy.
    Melis M; de Swart J; de Visser M; Berndsen SC; Koelewijn S; Valkema R; Boerman OC; Krenning EP; de Jong M
    J Nucl Med; 2010 Dec; 51(12):1962-8. PubMed ID: 21078795
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of the NSAID diclofenac on 99mTc-MAG3 and 99mTc-DTPA renography.
    Mustafa S; Elgazzar AH
    J Nucl Med; 2013 May; 54(5):801-6. PubMed ID: 23528384
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.