256 related articles for article (PubMed ID: 33087507)
1. Glutaminase Inhibitors Induce Thiol-Mediated Oxidative Stress and Radiosensitization in Treatment-Resistant Cervical Cancers.
Rashmi R; Jayachandran K; Zhang J; Menon V; Muhammad N; Zahner M; Ruiz F; Zhang S; Cho K; Wang Y; Huang X; Huang Y; McCormick ML; Rogers BE; Spitz DR; Patti GJ; Schwarz JK
Mol Cancer Ther; 2020 Dec; 19(12):2465-2475. PubMed ID: 33087507
[TBL] [Abstract][Full Text] [Related]
2. Radioresistant Cervical Cancers Are Sensitive to Inhibition of Glycolysis and Redox Metabolism.
Rashmi R; Huang X; Floberg JM; Elhammali AE; McCormick ML; Patti GJ; Spitz DR; Schwarz JK
Cancer Res; 2018 Mar; 78(6):1392-1403. PubMed ID: 29339540
[TBL] [Abstract][Full Text] [Related]
3. The glutaminase inhibitor telaglenastat enhances the antitumor activity of signal transduction inhibitors everolimus and cabozantinib in models of renal cell carcinoma.
Emberley E; Pan A; Chen J; Dang R; Gross M; Huang T; Li W; MacKinnon A; Singh D; Sotirovska N; Steggerda SM; Wang T; Parlati F
PLoS One; 2021; 16(11):e0259241. PubMed ID: 34731180
[TBL] [Abstract][Full Text] [Related]
4. Enhancement of Radiation Response in Breast Cancer Stem Cells by Inhibition of Thioredoxin- and Glutathione-Dependent Metabolism.
Rodman SN; Spence JM; Ronnfeldt TJ; Zhu Y; Solst SR; O'Neill RA; Allen BG; Guan X; Spitz DR; Fath MA
Radiat Res; 2016 Oct; 186(4):385-395. PubMed ID: 27643875
[TBL] [Abstract][Full Text] [Related]
5. Glutaminase inhibition with telaglenastat (CB-839) improves treatment response in combination with ionizing radiation in head and neck squamous cell carcinoma models.
Wicker CA; Hunt BG; Krishnan S; Aziz K; Parajuli S; Palackdharry S; Elaban WR; Wise-Draper TM; Mills GB; Waltz SE; Takiar V
Cancer Lett; 2021 Apr; 502():180-188. PubMed ID: 33450358
[TBL] [Abstract][Full Text] [Related]
6. GLS-driven glutamine catabolism contributes to prostate cancer radiosensitivity by regulating the redox state, stemness and ATG5-mediated autophagy.
Mukha A; Kahya U; Linge A; Chen O; Löck S; Lukiyanchuk V; Richter S; Alves TC; Peitzsch M; Telychko V; Skvortsov S; Negro G; Aschenbrenner B; Skvortsova II; Mirtschink P; Lohaus F; Hölscher T; Neubauer H; Rivandi M; Labitzky V; Lange T; Franken A; Behrens B; Stoecklein NH; Toma M; Sommer U; Zschaeck S; Rehm M; Eisenhofer G; Schwager C; Abdollahi A; Groeben C; Kunz-Schughart LA; Baretton GB; Baumann M; Krause M; Peitzsch C; Dubrovska A
Theranostics; 2021; 11(16):7844-7868. PubMed ID: 34335968
[TBL] [Abstract][Full Text] [Related]
7. Susceptibility of human head and neck cancer cells to combined inhibition of glutathione and thioredoxin metabolism.
Sobhakumari A; Love-Homan L; Fletcher EV; Martin SM; Parsons AD; Spitz DR; Knudson CM; Simons AL
PLoS One; 2012; 7(10):e48175. PubMed ID: 23118946
[TBL] [Abstract][Full Text] [Related]
8. Phosphatidylinositol 3-kinase inhibition by LY294002 radiosensitizes human cervical cancer cell lines.
Lee CM; Fuhrman CB; Planelles V; Peltier MR; Gaffney DK; Soisson AP; Dodson MK; Tolley HD; Green CL; Zempolich KA
Clin Cancer Res; 2006 Jan; 12(1):250-6. PubMed ID: 16397049
[TBL] [Abstract][Full Text] [Related]
9. Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer.
Grinde MT; Hilmarsdottir B; Tunset HM; Henriksen IM; Kim J; Haugen MH; Rye MB; Mælandsmo GM; Moestue SA
Breast Cancer Res; 2019 May; 21(1):61. PubMed ID: 31088535
[TBL] [Abstract][Full Text] [Related]
10. Glutaminase inhibitor CB-839 increases radiation sensitivity of lung tumor cells and human lung tumor xenografts in mice.
Boysen G; Jamshidi-Parsian A; Davis MA; Siegel ER; Simecka CM; Kore RA; Dings RPM; Griffin RJ
Int J Radiat Biol; 2019 Apr; 95(4):436-442. PubMed ID: 30557074
[TBL] [Abstract][Full Text] [Related]
11. Targeting redox homeostasis in rhabdomyosarcoma cells: GSH-depleting agents enhance auranofin-induced cell death.
Habermann KJ; Grünewald L; van Wijk S; Fulda S
Cell Death Dis; 2017 Oct; 8(10):e3067. PubMed ID: 28981107
[TBL] [Abstract][Full Text] [Related]
12. Knock-down of glutaminase 2 expression decreases glutathione, NADH, and sensitizes cervical cancer to ionizing radiation.
Xiang L; Xie G; Liu C; Zhou J; Chen J; Yu S; Li J; Pang X; Shi H; Liang H
Biochim Biophys Acta; 2013 Dec; 1833(12):2996-3005. PubMed ID: 23954443
[TBL] [Abstract][Full Text] [Related]
13. Phosphoinositide-3-kinase inhibition enhances radiosensitization of cervical cancer in vivo.
Liu Y; Cui B; Qiao Y; Zhang Y; Tian Y; Jiang J; Ma D; Kong B
Int J Gynecol Cancer; 2011 Jan; 21(1):100-5. PubMed ID: 21330835
[TBL] [Abstract][Full Text] [Related]
14. Glutamine Addiction in Kidney Cancer Suppresses Oxidative Stress and Can Be Exploited for Real-Time Imaging.
Abu Aboud O; Habib SL; Trott J; Stewart B; Liang S; Chaudhari AJ; Sutcliffe J; Weiss RH
Cancer Res; 2017 Dec; 77(23):6746-6758. PubMed ID: 29021138
[TBL] [Abstract][Full Text] [Related]
15. Enhancement of carboplatin-mediated lung cancer cell killing by simultaneous disruption of glutathione and thioredoxin metabolism.
Fath MA; Ahmad IM; Smith CJ; Spence J; Spitz DR
Clin Cancer Res; 2011 Oct; 17(19):6206-17. PubMed ID: 21844013
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of the MYC-Regulated Glutaminase Metabolic Axis Is an Effective Synthetic Lethal Approach for Treating Chemoresistant Ovarian Cancers.
Shen YA; Hong J; Asaka R; Asaka S; Hsu FC; Suryo Rahmanto Y; Jung JG; Chen YW; Yen TT; Tomaszewski A; Zhang C; Attarwala N; DeMarzo AM; Davidson B; Chuang CM; Chen X; Gaillard S; Le A; Shih IM; Wang TL
Cancer Res; 2020 Oct; 80(20):4514-4526. PubMed ID: 32859605
[TBL] [Abstract][Full Text] [Related]
17. 2-Deoxy-D-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism.
Lin X; Zhang F; Bradbury CM; Kaushal A; Li L; Spitz DR; Aft RL; Gius D
Cancer Res; 2003 Jun; 63(12):3413-7. PubMed ID: 12810678
[TBL] [Abstract][Full Text] [Related]
18. Combined inhibition of glycolysis, the pentose cycle, and thioredoxin metabolism selectively increases cytotoxicity and oxidative stress in human breast and prostate cancer.
Li L; Fath MA; Scarbrough PM; Watson WH; Spitz DR
Redox Biol; 2015; 4():127-35. PubMed ID: 25560241
[TBL] [Abstract][Full Text] [Related]
19. Targeted Inhibition of Glutamine-Dependent Glutathione Metabolism Overcomes Death Resistance Induced by Chronic Cycling Hypoxia.
Matschke J; Riffkin H; Klein D; Handrick R; Lüdemann L; Metzen E; Shlomi T; Stuschke M; Jendrossek V
Antioxid Redox Signal; 2016 Jul; 25(2):89-107. PubMed ID: 27021152
[TBL] [Abstract][Full Text] [Related]
20. Targeting Glutaminolysis to Treat Multiple Myeloma: An
Li C; Feng Y; Wang W; Xu L; Zhang M; Yao Y; Wu X; Zhang Q; Huang W; Wang X; Li X; Ying P; Shang L
Anticancer Agents Med Chem; 2023; 23(7):779-785. PubMed ID: 36065917
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
