BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

362 related articles for article (PubMed ID: 33087509)

  • 1. Inhibition of Lysosomal Function Mitigates Protective Mitophagy and Augments Ceramide Nanoliposome-Induced Cell Death in Head and Neck Squamous Cell Carcinoma.
    Shaw JJP; Boyer TL; Venner E; Beck PJ; Slamowitz T; Caste T; Hickman A; Raymond MH; Costa-Pinheiro P; Jameson MJ; Fox TE; Kester M
    Mol Cancer Ther; 2020 Dec; 19(12):2621-2633. PubMed ID: 33087509
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pivotal role of mitophagy in response of acute myelogenous leukemia to a ceramide-tamoxifen-containing drug regimen.
    Morad SAF; MacDougall MR; Abdelmageed N; Kao LP; Feith DJ; Tan SF; Kester M; Loughran TP; Wang HG; Cabot MC
    Exp Cell Res; 2019 Aug; 381(2):256-264. PubMed ID: 31112736
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Grape seed extract targets mitochondrial electron transport chain complex III and induces oxidative and metabolic stress leading to cytoprotective autophagy and apoptotic death in human head and neck cancer cells.
    Shrotriya S; Deep G; Lopert P; Patel M; Agarwal R; Agarwal C
    Mol Carcinog; 2015 Dec; 54(12):1734-47. PubMed ID: 25557495
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lysosomal degradation of CD44 mediates ceramide nanoliposome-induced anoikis and diminished extravasation in metastatic carcinoma cells.
    Haakenson JK; Khokhlatchev AV; Choi YJ; Linton SS; Zhang P; Zaki PM; Fu C; Cooper TK; Manni A; Zhu J; Fox TE; Dong C; Kester M
    J Biol Chem; 2015 Mar; 290(13):8632-43. PubMed ID: 25681441
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Autophagy blockade sensitizes human head and neck squamous cell carcinoma towards CYT997 through enhancing excessively high reactive oxygen species-induced apoptosis.
    Gao L; Zhao X; Lang L; Shay C; Andrew Yeudall W; Teng Y
    J Mol Med (Berl); 2018 Sep; 96(9):929-938. PubMed ID: 30022281
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulated Cell Death of Lymphoma Cells after Graded Mitochondrial Damage is Differentially Affected by Drugs Targeting Cell Stress Responses.
    Lombardo T; Folgar MG; Salaverry L; Rey-Roldán E; Alvarez EM; Carreras MC; Kornblihtt L; Blanco GA
    Basic Clin Pharmacol Toxicol; 2018 May; 122(5):489-500. PubMed ID: 29205851
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Disruption of the superoxide anions-mitophagy regulation axis mediates copper oxide nanoparticles-induced vascular endothelial cell death.
    Zhang J; Wang B; Wang H; He H; Wu Q; Qin X; Yang X; Chen L; Xu G; Yuan Z; Yi Q; Zou Z; Yu C
    Free Radic Biol Med; 2018 Dec; 129():268-278. PubMed ID: 30248444
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Berberine attenuated the cytotoxicity induced by t-BHP via inhibiting oxidative stress and mitochondria dysfunction in PC-12 cells.
    Li Z; Jiang T; Lu Q; Xu K; He J; Xie L; Chen Z; Zheng Z; Ye L; Xu K; Zhang H; Hu A
    Cell Mol Neurobiol; 2020 May; 40(4):587-602. PubMed ID: 31828466
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The dual PI3K/mTOR inhibitor NVP-BEZ235 and chloroquine synergize to trigger apoptosis via mitochondrial-lysosomal cross-talk.
    Seitz C; Hugle M; Cristofanon S; Tchoghandjian A; Fulda S
    Int J Cancer; 2013 Jun; 132(11):2682-93. PubMed ID: 23151917
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy.
    Sentelle RD; Senkal CE; Jiang W; Ponnusamy S; Gencer S; Selvam SP; Ramshesh VK; Peterson YK; Lemasters JJ; Szulc ZM; Bielawski J; Ogretmen B
    Nat Chem Biol; 2012 Oct; 8(10):831-8. PubMed ID: 22922758
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mitophagy-lysosomal pathway is involved in silver nanoparticle-induced apoptosis in A549 cells.
    Li J; Chang X; Shang M; Niu S; Zhang W; Zhang B; Huang W; Wu T; Zhang T; Tang M; Xue Y
    Ecotoxicol Environ Saf; 2021 Jan; 208():111463. PubMed ID: 33130480
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The autophagic- lysosomal pathway determines the fate of glial cells under manganese- induced oxidative stress conditions.
    Gorojod RM; Alaimo A; Porte Alcon S; Pomilio C; Saravia F; Kotler ML
    Free Radic Biol Med; 2015 Oct; 87():237-51. PubMed ID: 26163003
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of PI3K/mTOR increased the sensitivity of hepatocellular carcinoma cells to cisplatin via interference with mitochondrial-lysosomal crosstalk.
    Sheng J; Shen L; Sun L; Zhang X; Cui R; Wang L
    Cell Prolif; 2019 May; 52(3):e12609. PubMed ID: 31033054
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cell type-dependent ROS and mitophagy response leads to apoptosis or necroptosis in neuroblastoma.
    Radogna F; Cerella C; Gaigneaux A; Christov C; Dicato M; Diederich M
    Oncogene; 2016 Jul; 35(29):3839-53. PubMed ID: 26640148
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nitazoxanide impairs mitophagy flux through ROS-mediated mitophagy initiation and lysosomal dysfunction in bladder cancer.
    Sun H; Ou T; Hu J; Yang Z; Lei Q; Li Y; Wang G; Li Y; Wu K; Wang S; Wu S
    Biochem Pharmacol; 2021 Aug; 190():114588. PubMed ID: 33957094
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A critical role of the transient receptor potential melastatin 2 channel in a positive feedback mechanism for reactive oxygen species-induced delayed cell death.
    Li X; Jiang LH
    J Cell Physiol; 2019 Apr; 234(4):3647-3660. PubMed ID: 30229906
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ceramide stress in survival versus lethal autophagy paradox: ceramide targets autophagosomes to mitochondria and induces lethal mitophagy.
    Jiang W; Ogretmen B
    Autophagy; 2013 Feb; 9(2):258-9. PubMed ID: 23182807
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys.
    Livingston MJ; Wang J; Zhou J; Wu G; Ganley IG; Hill JA; Yin XM; Dong Z
    Autophagy; 2019 Dec; 15(12):2142-2162. PubMed ID: 31066324
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CLU (clusterin) and PPARGC1A/PGC1α coordinately control mitophagy and mitochondrial biogenesis for oral cancer cell survival.
    Praharaj PP; Patra S; Singh A; Panigrahi DP; Lee HY; Kabir MF; Hossain MK; Patra SK; Patro BS; Patil S; Klionsky DJ; Chae HJ; Bhutia SK
    Autophagy; 2024 Jun; 20(6):1359-1382. PubMed ID: 38447939
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation.
    Shen YQ; Guerra-Librero A; Fernandez-Gil BI; Florido J; García-López S; Martinez-Ruiz L; Mendivil-Perez M; Soto-Mercado V; Acuña-Castroviejo D; Ortega-Arellano H; Carriel V; Diaz-Casado ME; Reiter RJ; Rusanova I; Nieto A; López LC; Escames G
    J Pineal Res; 2018 Apr; 64(3):. PubMed ID: 29247557
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.