These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. One-pot synthesis of spiro(indoline-3,4'-pyrazolo[3,4-b]pyridine)-5'-carbonitriles as p53-MDM2 interaction inhibitors. Ibrahim HS; Eldehna WM; Fallacara AL; Ahmed ER; Ghabbour HA; Elaasser MM; Botta M; Abou-Seri SM; Abdel-Aziz HA Future Med Chem; 2018 Dec; 10(24):2771-2789. PubMed ID: 30526032 [TBL] [Abstract][Full Text] [Related]
3. Synthesis, anticancer activity and molecular modeling studies of 1,2,4-triazole derivatives as EGFR inhibitors. El-Sherief HAM; Youssif BGM; Abbas Bukhari SN; Abdelazeem AH; Abdel-Aziz M; Abdel-Rahman HM Eur J Med Chem; 2018 Aug; 156():774-789. PubMed ID: 30055463 [TBL] [Abstract][Full Text] [Related]
4. Design and synthesis of new pyranoquinolinone heteroannulated to triazolopyrimidine of potential apoptotic antiproliferative activity. Ramadan M; Abd El-Aziz M; Elshaier YAMM; Youssif BGM; Brown AB; Fathy HM; Aly AA Bioorg Chem; 2020 Dec; 105():104392. PubMed ID: 33137557 [TBL] [Abstract][Full Text] [Related]
5. Synthesis and antiproliferative activity of 8-hydroxyquinoline derivatives containing a 1,2,3-triazole moiety. Freitas LB; Borgati TF; de Freitas RP; Ruiz AL; Marchetti GM; de Carvalho JE; da Cunha EF; Ramalho TC; Alves RB Eur J Med Chem; 2014 Sep; 84():595-604. PubMed ID: 25062010 [TBL] [Abstract][Full Text] [Related]
6. Design and synthesis of novel 1,2,3-triazole-dithiocarbamate hybrids as potential anticancer agents. Duan YC; Ma YC; Zhang E; Shi XJ; Wang MM; Ye XW; Liu HM Eur J Med Chem; 2013 Apr; 62():11-9. PubMed ID: 23353743 [TBL] [Abstract][Full Text] [Related]
7. Design, Synthesis, and Alimujiang Y; Maimaiti A; Ablise M; Yang Z; Liu Z; Wang Y; Mutalipu Z; Yan T Anticancer Agents Med Chem; 2024; 24(6):423-435. PubMed ID: 38204258 [TBL] [Abstract][Full Text] [Related]
8. Design, Synthesis and Antiproliferative Evaluation of Novel 1,2,4-Triazole/Schiff Base Hybrids with EGFR and B-RAF Inhibitory Activities. El-Sherief HAM; Youssif BGM; Abdelazeem AH; Abdel-Aziz M; Abdel-Rahman HM Anticancer Agents Med Chem; 2019; 19(5):697-706. PubMed ID: 30582484 [TBL] [Abstract][Full Text] [Related]
9. Design and Synthesis of Novel Dehydroepiandrosterone Analogues as Potent Antiproliferative Agents. Huang X; Shen QK; Zhang HJ; Li JL; Tian YS; Quan ZS Molecules; 2018 Sep; 23(9):. PubMed ID: 30177642 [TBL] [Abstract][Full Text] [Related]
10. Cytotoxic 1,2,3-Triazoles as Potential Leads Targeting the S100A2-p53 Complex: Synthesis and Cytotoxicity. Sun J; Baker JR; Russell CC; Cossar PJ; Ngoc Thuy Pham H; Sakoff JA; Scarlett CJ; McCluskey A ChemMedChem; 2021 Sep; 16(18):2864-2881. PubMed ID: 34047450 [TBL] [Abstract][Full Text] [Related]
11. Synthesis and antiproliferative evaluation of novel 1,2,4-triazole derivatives incorporating benzisoselenazolone scaffold. Li BL; Li B; Zhang RL; Zhao JJ; Wang XF; Liu YM; Shi YP; Liu JB; Chen BQ Bioorg Med Chem Lett; 2016 Feb; 26(4):1279-81. PubMed ID: 26786698 [TBL] [Abstract][Full Text] [Related]
12. Design, Synthesis, In Vitro Anti-cancer Activity, ADMET Profile and Molecular Docking of Novel Triazolo[3,4-a]phthalazine Derivatives Targeting VEGFR-2 Enzyme. El-Helby AA; Sakr H; Ayyad RRA; El-Adl K; Ali MM; Khedr F Anticancer Agents Med Chem; 2018; 18(8):1184-1196. PubMed ID: 29651967 [TBL] [Abstract][Full Text] [Related]
13. A Diarylpentanoid with Potential Activation of the p53 Pathway: Combination of in silico Screening Studies, Synthesis, and Biological Activity Evaluation. Moreira J; Almeida J; Loureiro JB; Ramos H; Palmeira A; Pinto MM; Saraiva L; Cidade H ChemMedChem; 2021 Oct; 16(19):2969-2981. PubMed ID: 34170069 [TBL] [Abstract][Full Text] [Related]
14. Novel Benzyloxyphenyl Pyrimidine-5-Carbonitrile Derivatives as Potential Apoptotic Antiproliferative Agents. Al-Mahmoudy A; Hassan A; Ibrahim T; Youssif BGM; Taher E; Tantawy M; Abdel-Aal E; Osman N Anticancer Agents Med Chem; 2022; 22(5):978-990. PubMed ID: 34126912 [TBL] [Abstract][Full Text] [Related]
15. Design, synthesis, molecular docking and anti-proliferative evaluations of [1,2,4]triazolo[4,3-a]quinoxaline derivatives as DNA intercalators and Topoisomerase II inhibitors. El-Adl K; El-Helby AA; Sakr H; Elwan A Bioorg Chem; 2020 Dec; 105():104399. PubMed ID: 33113414 [TBL] [Abstract][Full Text] [Related]
16. Identification of new inhibitors of Mdm2-p53 interaction via pharmacophore and structure-based virtual screening. Atatreh N; Ghattas MA; Bardaweel SK; Rawashdeh SA; Sorkhy MA Drug Des Devel Ther; 2018; 12():3741-3752. PubMed ID: 30464405 [TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of some novel 1,2,3-triazole hybrids of myrrhanone B isolated from Commiphora mukul gum resin: Identification of potent antiproliferative leads active against prostate cancer cells (PC-3). Madasu C; Karri S; Sangaraju R; Sistla R; Uppuluri MV Eur J Med Chem; 2020 Feb; 188():111974. PubMed ID: 31883489 [TBL] [Abstract][Full Text] [Related]
18. Spirooxindole-derived morpholine-fused-1,2,3-triazoles: Design, synthesis, cytotoxicity and apoptosis inducing studies. Senwar KR; Sharma P; Reddy TS; Jeengar MK; Nayak VL; Naidu VG; Kamal A; Shankaraiah N Eur J Med Chem; 2015 Sep; 102():413-24. PubMed ID: 26301558 [TBL] [Abstract][Full Text] [Related]
19. Cytotoxicity, molecular modeling, cell cycle arrest, and apoptotic induction induced by novel tetrahydro-[1,2,4]triazolo[3,4-a]isoquinoline chalcones. Mohamed MF; Hassaneen HM; Abdelhamid IA Eur J Med Chem; 2018 Jan; 143():532-541. PubMed ID: 29207336 [TBL] [Abstract][Full Text] [Related]
20. Design, synthesis and in vitro and in vivo antitumour activity of 3-benzylideneindolin-2-one derivatives, a novel class of small-molecule inhibitors of the MDM2-p53 interaction. Zheng GH; Shen JJ; Zhan YC; Yi H; Xue ST; Wang Z; Ji XY; Li ZR Eur J Med Chem; 2014 Jun; 81():277-88. PubMed ID: 24852275 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]