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4. Neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab compared with neoadjuvant chemotherapy alone in patients with early-stage non-small-cell lung cancer (KEYNOTE-671): a randomised, double-blind, placebo-controlled, phase 3 trial. Spicer JD; Garassino MC; Wakelee H; Liberman M; Kato T; Tsuboi M; Lee SH; Chen KN; Dooms C; Majem M; Eigendorff E; Martinengo GL; Bylicki O; Rodríguez-Abreu D; Chaft JE; Novello S; Yang J; Arunachalam A; Keller SM; Samkari A; Gao S; Lancet; 2024 Sep; 404(10459):1240-1252. PubMed ID: 39288781 [TBL] [Abstract][Full Text] [Related]
5. Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer (KEYNOTE-355): a randomised, placebo-controlled, double-blind, phase 3 clinical trial. Cortes J; Cescon DW; Rugo HS; Nowecki Z; Im SA; Yusof MM; Gallardo C; Lipatov O; Barrios CH; Holgado E; Iwata H; Masuda N; Otero MT; Gokmen E; Loi S; Guo Z; Zhao J; Aktan G; Karantza V; Schmid P; Lancet; 2020 Dec; 396(10265):1817-1828. PubMed ID: 33278935 [TBL] [Abstract][Full Text] [Related]
6. Pembrolizumab versus investigator-choice chemotherapy for metastatic triple-negative breast cancer (KEYNOTE-119): a randomised, open-label, phase 3 trial. Winer EP; Lipatov O; Im SA; Goncalves A; Muñoz-Couselo E; Lee KS; Schmid P; Tamura K; Testa L; Witzel I; Ohtani S; Turner N; Zambelli S; Harbeck N; Andre F; Dent R; Zhou X; Karantza V; Mejia J; Cortes J; Lancet Oncol; 2021 Apr; 22(4):499-511. PubMed ID: 33676601 [TBL] [Abstract][Full Text] [Related]
7. Pembrolizumab plus concurrent chemoradiotherapy versus placebo plus concurrent chemoradiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck (KEYNOTE-412): a randomised, double-blind, phase 3 trial. Machiels JP; Tao Y; Licitra L; Burtness B; Tahara M; Rischin D; Alves G; Lima IPF; Hughes BGM; Pointreau Y; Aksoy S; Laban S; Greil R; Burian M; Hetnał M; Delord JP; Mesía R; Taberna M; Waldron JN; Simon C; Grégoire V; Harrington KJ; Swaby RF; Zhang Y; Gumuscu B; Bidadi B; Siu LL; Lancet Oncol; 2024 May; 25(5):572-587. PubMed ID: 38561010 [TBL] [Abstract][Full Text] [Related]
8. Pembrolizumab with or without radiation therapy for metastatic non-small cell lung cancer: a randomized phase I/II trial. Welsh J; Menon H; Chen D; Verma V; Tang C; Altan M; Hess K; de Groot P; Nguyen QN; Varghese R; Comeaux NI; Simon G; Skoulidis F; Chang JY; Papdimitrakopoulou V; Lin SH; Heymach JV J Immunother Cancer; 2020 Oct; 8(2):. PubMed ID: 33051340 [TBL] [Abstract][Full Text] [Related]
9. Ramucirumab plus pembrolizumab in patients with previously treated advanced non-small-cell lung cancer, gastro-oesophageal cancer, or urothelial carcinomas (JVDF): a multicohort, non-randomised, open-label, phase 1a/b trial. Herbst RS; Arkenau HT; Santana-Davila R; Calvo E; Paz-Ares L; Cassier PA; Bendell J; Penel N; Krebs MG; Martin-Liberal J; Isambert N; Soriano A; Wermke M; Cultrera J; Gao L; Widau RC; Mi G; Jin J; Ferry D; Fuchs CS; Petrylak DP; Chau I Lancet Oncol; 2019 Aug; 20(8):1109-1123. PubMed ID: 31301962 [TBL] [Abstract][Full Text] [Related]
10. Pembrolizumab or placebo with chemoradiotherapy followed by pembrolizumab or placebo for newly diagnosed, high-risk, locally advanced cervical cancer (ENGOT-cx11/GOG-3047/KEYNOTE-A18): a randomised, double-blind, phase 3 clinical trial. Lorusso D; Xiang Y; Hasegawa K; Scambia G; Leiva M; Ramos-Elias P; Acevedo A; Sukhin V; Cloven N; Pereira de Santana Gomes AJ; Contreras Mejía F; Reiss A; Ayhan A; Lee JY; Saevets V; Zagouri F; Gilbert L; Sehouli J; Tharavichitkul E; Lindemann K; Lazzari R; Chang CL; Lampé R; Zhu H; Oaknin A; Christiaens M; Polterauer S; Usami T; Li K; Yamada K; Toker S; Keefe SM; Pignata S; Duska LR; Lancet; 2024 Apr; 403(10434):1341-1350. PubMed ID: 38521086 [TBL] [Abstract][Full Text] [Related]
11. Pembrolizumab or placebo with chemoradiotherapy followed by pembrolizumab or placebo for newly diagnosed, high-risk, locally advanced cervical cancer (ENGOT-cx11/GOG-3047/KEYNOTE-A18): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 trial. Lorusso D; Xiang Y; Hasegawa K; Scambia G; Leiva M; Ramos-Elias P; Acevedo A; Cvek J; Randall L; Pereira de Santana Gomes AJ; Contreras Mejía F; Helpman L; Akıllı H; Lee JY; Saevets V; Zagouri F; Gilbert L; Sehouli J; Tharavichitkul E; Lindemann K; Colombo N; Chang CL; Bednarikova M; Zhu H; Oaknin A; Christiaens M; Petru E; Usami T; Liu P; Yamada K; Toker S; Keefe SM; Pignata S; Duska LR; Lancet; 2024 Oct; 404(10460):1321-1332. PubMed ID: 39288779 [TBL] [Abstract][Full Text] [Related]
12. Standard-dose versus high-dose conformal radiotherapy with concurrent and consolidation carboplatin plus paclitaxel with or without cetuximab for patients with stage IIIA or IIIB non-small-cell lung cancer (RTOG 0617): a randomised, two-by-two factorial phase 3 study. Bradley JD; Paulus R; Komaki R; Masters G; Blumenschein G; Schild S; Bogart J; Hu C; Forster K; Magliocco A; Kavadi V; Garces YI; Narayan S; Iyengar P; Robinson C; Wynn RB; Koprowski C; Meng J; Beitler J; Gaur R; Curran W; Choy H Lancet Oncol; 2015 Feb; 16(2):187-99. PubMed ID: 25601342 [TBL] [Abstract][Full Text] [Related]
13. Pembrolizumab plus axitinib versus sunitinib monotherapy as first-line treatment of advanced renal cell carcinoma (KEYNOTE-426): extended follow-up from a randomised, open-label, phase 3 trial. Powles T; Plimack ER; Soulières D; Waddell T; Stus V; Gafanov R; Nosov D; Pouliot F; Melichar B; Vynnychenko I; Azevedo SJ; Borchiellini D; McDermott RS; Bedke J; Tamada S; Yin L; Chen M; Molife LR; Atkins MB; Rini BI Lancet Oncol; 2020 Dec; 21(12):1563-1573. PubMed ID: 33284113 [TBL] [Abstract][Full Text] [Related]
14. Pembrolizumab in patients with advanced non-small-cell lung cancer (KEYNOTE-001): 3-year results from an open-label, phase 1 study. Leighl NB; Hellmann MD; Hui R; Carcereny E; Felip E; Ahn MJ; Eder JP; Balmanoukian AS; Aggarwal C; Horn L; Patnaik A; Gubens M; Ramalingam SS; Lubiniecki GM; Zhang J; Piperdi B; Garon EB Lancet Respir Med; 2019 Apr; 7(4):347-357. PubMed ID: 30876831 [TBL] [Abstract][Full Text] [Related]
15. Health-related quality-of-life results for pembrolizumab versus chemotherapy in advanced, PD-L1-positive NSCLC (KEYNOTE-024): a multicentre, international, randomised, open-label phase 3 trial. Brahmer JR; Rodríguez-Abreu D; Robinson AG; Hui R; Csőszi T; Fülöp A; Gottfried M; Peled N; Tafreshi A; Cuffe S; O'Brien M; Rao S; Hotta K; Zhang J; Lubiniecki GM; Deitz AC; Rangwala R; Reck M Lancet Oncol; 2017 Dec; 18(12):1600-1609. PubMed ID: 29129441 [TBL] [Abstract][Full Text] [Related]
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20. Epacadostat plus pembrolizumab versus placebo plus pembrolizumab in patients with unresectable or metastatic melanoma (ECHO-301/KEYNOTE-252): a phase 3, randomised, double-blind study. Long GV; Dummer R; Hamid O; Gajewski TF; Caglevic C; Dalle S; Arance A; Carlino MS; Grob JJ; Kim TM; Demidov L; Robert C; Larkin J; Anderson JR; Maleski J; Jones M; Diede SJ; Mitchell TC Lancet Oncol; 2019 Aug; 20(8):1083-1097. PubMed ID: 31221619 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]