206 related articles for article (PubMed ID: 33096927)
1. Thermodynamic Insights by Microscale Thermophoresis into Translesion DNA Synthesis Catalyzed by DNA Polymerases Across a Lesion of Antitumor Platinum-Acridine Complex.
Hreusova M; Novakova O; Brabec V
Int J Mol Sci; 2020 Oct; 21(20):. PubMed ID: 33096927
[TBL] [Abstract][Full Text] [Related]
2. Processing and Bypass of a Site-Specific DNA Adduct of the Cytotoxic Platinum-Acridinylthiourea Conjugate by Polymerases Involved in DNA Repair: Biochemical and Thermodynamic Aspects.
Hreusova M; Brabec V; Novakova O
Int J Mol Sci; 2021 Oct; 22(19):. PubMed ID: 34639179
[TBL] [Abstract][Full Text] [Related]
3. Replacement of a thiourea with an amidine group in a monofunctional platinum-acridine antitumor agent. Effect on DNA interactions, DNA adduct recognition and repair.
Kostrhunova H; Malina J; Pickard AJ; Stepankova J; Vojtiskova M; Kasparkova J; Muchova T; Rohlfing ML; Bierbach U; Brabec V
Mol Pharm; 2011 Oct; 8(5):1941-54. PubMed ID: 21806015
[TBL] [Abstract][Full Text] [Related]
4. Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug.
Brabec V; Malina J; Margiotta N; Natile G; Kasparkova J
Chemistry; 2012 Nov; 18(48):15439-48. PubMed ID: 23065963
[TBL] [Abstract][Full Text] [Related]
5. Toward understanding the mutagenicity of an environmental carcinogen: structural insights into nucleotide incorporation preferences.
Perlow RA; Broyde S
J Mol Biol; 2002 Sep; 322(2):291-309. PubMed ID: 12217692
[TBL] [Abstract][Full Text] [Related]
6. Conformational Flexibility of the Benzyl-Guanine Adduct in a Bypass Polymerase Active Site Permits Replication: Insights from Molecular Dynamics Simulations.
Wilson KA; Wetmore SD
Chem Res Toxicol; 2017 Nov; 30(11):2013-2022. PubMed ID: 28810119
[TBL] [Abstract][Full Text] [Related]
7. The N2-ethylguanine and the O6-ethyl- and O6-methylguanine lesions in DNA: contrasting responses from the "bypass" DNA polymerase eta and the replicative DNA polymerase alpha.
Perrino FW; Blans P; Harvey S; Gelhaus SL; McGrath C; Akman SA; Jenkins GS; LaCourse WR; Fishbein JC
Chem Res Toxicol; 2003 Dec; 16(12):1616-23. PubMed ID: 14680376
[TBL] [Abstract][Full Text] [Related]
8. Adduct size limits efficient and error-free bypass across bulky N2-guanine DNA lesions by human DNA polymerase eta.
Choi JY; Guengerich FP
J Mol Biol; 2005 Sep; 352(1):72-90. PubMed ID: 16061253
[TBL] [Abstract][Full Text] [Related]
9. Specific incorporation of an artificial nucleotide opposite a mutagenic DNA adduct by a DNA polymerase.
Wyss LA; Nilforoushan A; Eichenseher F; Suter U; Blatter N; Marx A; Sturla SJ
J Am Chem Soc; 2015 Jan; 137(1):30-3. PubMed ID: 25490521
[TBL] [Abstract][Full Text] [Related]
10. Polymerization past the N2-isopropylguanine and the N6-isopropyladenine DNA lesions with the translesion synthesis DNA polymerases eta and iota and the replicative DNA polymerase alpha.
Perrino FW; Harvey S; Blans P; Gelhaus S; Lacourse WR; Fishbein JC
Chem Res Toxicol; 2005 Sep; 18(9):1451-61. PubMed ID: 16167838
[TBL] [Abstract][Full Text] [Related]
11. Translesion DNA Synthesis Across Lesions Induced by Oxidative Products of Pyrimidines: An Insight into the Mechanism by Microscale Thermophoresis.
Hrabina O; Brabec V; Novakova O
Int J Mol Sci; 2019 Oct; 20(20):. PubMed ID: 31658654
[TBL] [Abstract][Full Text] [Related]
12. Solution structural study of a DNA duplex containing the guanine-N7 adduct formed by a cytotoxic platinum-acridine hybrid agent.
Baruah H; Wright MW; Bierbach U
Biochemistry; 2005 Apr; 44(16):6059-70. PubMed ID: 15835895
[TBL] [Abstract][Full Text] [Related]
13. Miscoding properties of 6alpha- and 6beta-diastereoisomers of the N(2)-(estradiol-6-yl)-2'-deoxyguanosine DNA adduct by Y-family human DNA polymerases.
Poon K; Itoh S; Suzuki N; Laxmi YR; Yoshizawa I; Shibutani S
Biochemistry; 2008 Jun; 47(25):6695-701. PubMed ID: 18512958
[TBL] [Abstract][Full Text] [Related]
14. Unprecedented monofunctional metalation of adenine nucleobase in guanine- and thymine-containing dinucleotide sequences by a cytotoxic platinum-acridine hybrid agent.
Barry CG; Baruah H; Bierbach U
J Am Chem Soc; 2003 Aug; 125(32):9629-37. PubMed ID: 12904029
[TBL] [Abstract][Full Text] [Related]
15. Extending the understanding of mutagenicity: structural insights into primer-extension past a benzo[a]pyrene diol epoxide-DNA adduct.
Perlow RA; Broyde S
J Mol Biol; 2003 Apr; 327(4):797-818. PubMed ID: 12654264
[TBL] [Abstract][Full Text] [Related]
16. Translesion synthesis DNA polymerases promote error-free replication through the minor-groove DNA adduct 3-deaza-3-methyladenine.
Yoon JH; Roy Choudhury J; Park J; Prakash S; Prakash L
J Biol Chem; 2017 Nov; 292(45):18682-18688. PubMed ID: 28939775
[TBL] [Abstract][Full Text] [Related]
17. Thermodynamics of translesion synthesis across a major DNA adduct of antitumor oxaliplatin: differential scanning calorimetric study.
Florian J; Brabec V
Chemistry; 2012 Feb; 18(6):1634-9. PubMed ID: 22213228
[TBL] [Abstract][Full Text] [Related]
18. Enzymatic bypass and the structural basis of miscoding opposite the DNA adduct 1,N
Ghodke PP; Mali JR; Patra A; Rizzo CJ; Guengerich FP; Egli M
J Biol Chem; 2021; 296():100642. PubMed ID: 33839151
[TBL] [Abstract][Full Text] [Related]
19. Miscoding properties of 2'-deoxyinosine, a nitric oxide-derived DNA Adduct, during translesion synthesis catalyzed by human DNA polymerases.
Yasui M; Suenaga E; Koyama N; Masutani C; Hanaoka F; Gruz P; Shibutani S; Nohmi T; Hayashi M; Honma M
J Mol Biol; 2008 Apr; 377(4):1015-23. PubMed ID: 18304575
[TBL] [Abstract][Full Text] [Related]
20. Molecular Insights into the Translesion Synthesis of Benzyl-Guanine from Molecular Dynamics Simulations: Structural Evidence of Mutagenic and Nonmutagenic Replication.
Wilson KA; Wetmore SD
Biochemistry; 2017 Apr; 56(13):1841-1853. PubMed ID: 28290677
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
