These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

331 related articles for article (PubMed ID: 33101276)

  • 1. Triggering Receptor Expressed on Myeloid Cell 2 R47H Exacerbates Immune Response in Alzheimer's Disease Brain.
    Korvatska O; Kiianitsa K; Ratushny A; Matsushita M; Beeman N; Chien WM; Satoh JI; Dorschner MO; Keene CD; Bammler TK; Bird TD; Raskind WH
    Front Immunol; 2020; 11():559342. PubMed ID: 33101276
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Alzheimer's disease-associated R47H TREM2 increases, but wild-type TREM2 decreases, microglial phagocytosis of synaptosomes and neuronal loss.
    Popescu AS; Butler CA; Allendorf DH; Piers TM; Mallach A; Roewe J; Reinhardt P; Cinti A; Redaelli L; Boudesco C; Pradier L; Pocock JM; Thornton P; Brown GC
    Glia; 2023 Apr; 71(4):974-990. PubMed ID: 36480007
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression and processing analyses of wild type and p.R47H TREM2 variant in Alzheimer's disease brains.
    Ma L; Allen M; Sakae N; Ertekin-Taner N; Graff-Radford NR; Dickson DW; Younkin SG; Sevlever D
    Mol Neurodegener; 2016 Nov; 11(1):72. PubMed ID: 27887626
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages.
    Hall-Roberts H; Agarwal D; Obst J; Smith TB; Monzón-Sandoval J; Di Daniel E; Webber C; James WS; Mead E; Davis JB; Cowley SA
    Alzheimers Res Ther; 2020 Nov; 12(1):151. PubMed ID: 33198789
    [TBL] [Abstract][Full Text] [Related]  

  • 5. iPSC-derived microglia carrying the TREM2 R47H/+ mutation are proinflammatory and promote synapse loss.
    Penney J; Ralvenius WT; Loon A; Cerit O; Dileep V; Milo B; Pao PC; Woolf H; Tsai LH
    Glia; 2024 Feb; 72(2):452-469. PubMed ID: 37969043
    [TBL] [Abstract][Full Text] [Related]  

  • 6. R47H Variant of TREM2 Associated With Alzheimer Disease in a Large Late-Onset Family: Clinical, Genetic, and Neuropathological Study.
    Korvatska O; Leverenz JB; Jayadev S; McMillan P; Kurtz I; Guo X; Rumbaugh M; Matsushita M; Girirajan S; Dorschner MO; Kiianitsa K; Yu CE; Brkanac Z; Garden GA; Raskind WH; Bird TD
    JAMA Neurol; 2015 Aug; 72(8):920-7. PubMed ID: 26076170
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prior activation state shapes the microglia response to antihuman TREM2 in a mouse model of Alzheimer's disease.
    Ellwanger DC; Wang S; Brioschi S; Shao Z; Green L; Case R; Yoo D; Weishuhn D; Rathanaswami P; Bradley J; Rao S; Cha D; Luan P; Sambashivan S; Gilfillan S; Hasson SA; Foltz IN; van Lookeren Campagne M; Colonna M
    Proc Natl Acad Sci U S A; 2021 Jan; 118(3):. PubMed ID: 33446504
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer's disease.
    Cheng-Hathaway PJ; Reed-Geaghan EG; Jay TR; Casali BT; Bemiller SM; Puntambekar SS; von Saucken VE; Williams RY; Karlo JC; Moutinho M; Xu G; Ransohoff RM; Lamb BT; Landreth GE
    Mol Neurodegener; 2018 Jun; 13(1):29. PubMed ID: 29859094
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A Trem2
    Tran KM; Kawauchi S; Kramár EA; Rezaie N; Liang HY; Sakr JS; Gomez-Arboledas A; Arreola MA; Cunha CD; Phan J; Wang S; Collins S; Walker A; Shi KX; Neumann J; Filimban G; Shi Z; Milinkeviciute G; Javonillo DI; Tran K; Gantuz M; Forner S; Swarup V; Tenner AJ; LaFerla FM; Wood MA; Mortazavi A; MacGregor GR; Green KN
    Mol Neurodegener; 2023 Feb; 18(1):12. PubMed ID: 36803190
    [TBL] [Abstract][Full Text] [Related]  

  • 10. IPSC-Derived Neuronal Cultures Carrying the Alzheimer's Disease Associated
    Martins S; Müller-Schiffmann A; Erichsen L; Bohndorf M; Wruck W; Sleegers K; Van Broeckhoven C; Korth C; Adjaye J
    Int J Mol Sci; 2020 Jun; 21(12):. PubMed ID: 32630447
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TREM2-activating antibodies abrogate the negative pleiotropic effects of the Alzheimer's disease variant
    Cheng Q; Danao J; Talreja S; Wen P; Yin J; Sun N; Li CM; Chui D; Tran D; Koirala S; Chen H; Foltz IN; Wang S; Sambashivan S
    J Biol Chem; 2018 Aug; 293(32):12620-12633. PubMed ID: 29599291
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Erythromyeloid-Derived TREM2: A Major Determinant of Alzheimer's Disease Pathology in Down Syndrome.
    Raha-Chowdhury R; Henderson JW; Raha AA; Stott SRW; Vuono R; Foscarin S; Wilson L; Annus T; Fincham R; Allinson K; Devalia V; Friedland RP; Holland A; Zaman SH
    J Alzheimers Dis; 2018; 61(3):1143-1162. PubMed ID: 29278889
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of FAK/Rac1/Cdc42-GTPase signaling ameliorates impaired microglial migration response to Aβ
    Rong Z; Cheng B; Zhong L; Ye X; Li X; Jia L; Li Y; Shue F; Wang N; Cheng Y; Huang X; Liu CC; Fryer JD; Wang X; Zhang YW; Zheng H
    FASEB J; 2020 Aug; 34(8):10984-10997. PubMed ID: 32613609
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer's disease.
    Claes C; Danhash EP; Hasselmann J; Chadarevian JP; Shabestari SK; England WE; Lim TE; Hidalgo JLS; Spitale RC; Davtyan H; Blurton-Jones M
    Mol Neurodegener; 2021 Jul; 16(1):50. PubMed ID: 34301296
    [TBL] [Abstract][Full Text] [Related]  

  • 15. AD-linked R47H-
    Sayed FA; Kodama L; Fan L; Carling GK; Udeochu JC; Le D; Li Q; Zhou L; Wong MY; Horowitz R; Ye P; Mathys H; Wang M; Niu X; Mazutis L; Jiang X; Wang X; Gao F; Brendel M; Telpoukhovskaia M; Tracy TE; Frost G; Zhou Y; Li Y; Qiu Y; Cheng Z; Yu G; Hardy J; Coppola G; Wang F; DeTure MA; Zhang B; Xie L; Trajnowski JQ; Lee VMY; Gong S; Sinha SC; Dickson DW; Luo W; Gan L
    Sci Transl Med; 2021 Dec; 13(622):eabe3947. PubMed ID: 34851693
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SHIP inhibition mediates select TREM2-induced microglial functions.
    Ramakrishnan GS; Berry WL; Pacherille A; Kerr WG; Chisholm JD; Pedicone C; Humphrey MB
    Mol Immunol; 2024 Jun; 170():35-45. PubMed ID: 38613944
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Trem2 Splicing and Expression are Preserved in a Human Aβ-producing, Rat Knock-in Model of Trem2-R47H Alzheimer's Risk Variant.
    Tambini MD; D'Adamio L
    Sci Rep; 2020 Mar; 10(1):4122. PubMed ID: 32139718
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans.
    Xiang X; Piers TM; Wefers B; Zhu K; Mallach A; Brunner B; Kleinberger G; Song W; Colonna M; Herms J; Wurst W; Pocock JM; Haass C
    Mol Neurodegener; 2018 Sep; 13(1):49. PubMed ID: 30185230
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular basis for the loss-of-function effects of the Alzheimer's disease-associated R47H variant of the immune receptor TREM2.
    Sudom A; Talreja S; Danao J; Bragg E; Kegel R; Min X; Richardson J; Zhang Z; Sharkov N; Marcora E; Thibault S; Bradley J; Wood S; Lim AC; Chen H; Wang S; Foltz IN; Sambashivan S; Wang Z
    J Biol Chem; 2018 Aug; 293(32):12634-12646. PubMed ID: 29794134
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism.
    Song WM; Joshita S; Zhou Y; Ulland TK; Gilfillan S; Colonna M
    J Exp Med; 2018 Mar; 215(3):745-760. PubMed ID: 29321225
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.