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5. Oral recombinant methioninase combined with oxaliplatinum and 5-fluorouracil regressed a colon cancer growing on the peritoneal surface in a patient-derived orthotopic xenograft mouse model. Park JH; Han Q; Zhao M; Tan Y; Higuchi T; Yoon SN; Sugisawa N; Yamamoto J; Bouvet M; Clary B; Singh SR; Hoffman RM Tissue Cell; 2019 Dec; 61():109-114. PubMed ID: 31759402 [TBL] [Abstract][Full Text] [Related]
6. Oral recombinant methioninase combined with paclitaxel arrests recalcitrant ovarian clear cell carcinoma growth in a patient-derived orthotopic xenograft (PDOX) nude-mouse model. Sugisawa N; Higuchi T; Han Q; Hozumi C; Yamamoto J; Tashiro Y; Nishino H; Kawaguchi K; Bouvet M; Murata T; Unno M; Hoffman RM Cancer Chemother Pharmacol; 2021 Jul; 88(1):61-67. PubMed ID: 33768300 [TBL] [Abstract][Full Text] [Related]
7. Targeting methionine with oral recombinant methioninase (o-rMETase) arrests a patient-derived orthotopic xenograft (PDOX) model of BRAF-V600E mutant melanoma: implications for chronic clinical cancer therapy and prevention. Kawaguchi K; Han Q; Li S; Tan Y; Igarashi K; Kiyuna T; Miyake K; Miyake M; Chmielowski B; Nelson SD; Russell TA; Dry SM; Li Y; Singh AS; Eckardt MA; Unno M; Eilber FC; Hoffman RM Cell Cycle; 2018; 17(3):356-361. PubMed ID: 29187018 [TBL] [Abstract][Full Text] [Related]
8. Combining Tumor-Selective Bacterial Therapy with Salmonella typhimurium A1-R and Cancer Metabolism Targeting with Oral Recombinant Methioninase Regressed an Ewing's Sarcoma in a Patient-Derived Orthotopic Xenograft Model. Miyake K; Kiyuna T; Li S; Han Q; Tan Y; Zhao M; Oshiro H; Kawaguchi K; Higuchi T; Zhang Z; Razmjooei S; Barangi M; Wangsiricharoen S; Murakami T; Singh AS; Li Y; Nelson SD; Eilber FC; Bouvet M; Hiroshima Y; Chishima T; Matsuyama R; Singh SR; Endo I; Hoffman RM Chemotherapy; 2018; 63(5):278-283. PubMed ID: 30673664 [TBL] [Abstract][Full Text] [Related]
9. Recombinant methioninase in combination with doxorubicin (DOX) overcomes first-line DOX resistance in a patient-derived orthotopic xenograft nude-mouse model of undifferentiated spindle-cell sarcoma. Igarashi K; Kawaguchi K; Li S; Han Q; Tan Y; Murakami T; Kiyuna T; Miyake K; Miyake M; Singh AS; Eckardt MA; Nelson SD; Russell TA; Dry SM; Li Y; Yamamoto N; Hayashi K; Kimura H; Miwa S; Tsuchiya H; Singh SR; Eilber FC; Hoffman RM Cancer Lett; 2018 Mar; 417():168-173. PubMed ID: 29306021 [TBL] [Abstract][Full Text] [Related]
10. Afterword: Oral Methioninase-Answer to Cancer and Fountain of Youth? Hoffman RM; Han Q; Kawaguchi K; Li S; Tan Y Methods Mol Biol; 2019; 1866():311-322. PubMed ID: 30725426 [TBL] [Abstract][Full Text] [Related]
11. Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model. Murakami T; Li S; Han Q; Tan Y; Kiyuna T; Igarashi K; Kawaguchi K; Hwang HK; Miyake K; Singh AS; Nelson SD; Dry SM; Li Y; Hiroshima Y; Lwin TM; DeLong JC; Chishima T; Tanaka K; Bouvet M; Endo I; Eilber FC; Hoffman RM Oncotarget; 2017 May; 8(22):35630-35638. PubMed ID: 28404944 [TBL] [Abstract][Full Text] [Related]
12. Efficacy of oral recombinant methioninase combined with oxaliplatinum and 5-fluorouracil on primary colon cancer in a patient-derived orthotopic xenograft mouse model. Park JH; Zhao M; Han Q; Sun Y; Higuchi T; Sugisawa N; Yamamoto J; Singh SR; Clary B; Bouvet M; Hoffman RM Biochem Biophys Res Commun; 2019 Oct; 518(2):306-310. PubMed ID: 31421825 [TBL] [Abstract][Full Text] [Related]
13. Efficacy of recombinant methioninase in combination with cisplatin on human colon tumors in nude mice. Tan Y; Sun X; Xu M; Tan X; Sasson A; Rashidi B; Han Q; Tan X; Wang X; An Z; Sun FX; Hoffman RM Clin Cancer Res; 1999 Aug; 5(8):2157-63. PubMed ID: 10473100 [TBL] [Abstract][Full Text] [Related]
14. High Efficacy of Recombinant Methioninase on Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Cancer. Hoffman RM; Murakami T; Kawaguchi K; Igarashi K; Tan Y; Li S; Han Q Methods Mol Biol; 2019; 1866():149-161. PubMed ID: 30725414 [TBL] [Abstract][Full Text] [Related]
15. Targeting altered cancer methionine metabolism with recombinant methioninase (rMETase) overcomes partial gemcitabine-resistance and regresses a patient-derived orthotopic xenograft (PDOX) nude mouse model of pancreatic cancer. Kawaguchi K; Miyake K; Han Q; Li S; Tan Y; Igarashi K; Lwin TM; Higuchi T; Kiyuna T; Miyake M; Oshiro H; Bouvet M; Unno M; Hoffman RM Cell Cycle; 2018; 17(7):868-873. PubMed ID: 29623758 [TBL] [Abstract][Full Text] [Related]
16. Oral-recombinant Methioninase Lowers the Effective Dose and Eliminates Toxicity of Cisplatinum for Primary Osteosarcoma of the Mammary Gland in a Patient-derived Orthotopic Xenograft Mouse Model. Masaki N; Han Q; Wu NF; Samonte C; Wu J; Hozumi C; Obara K; Kubota Y; Aoki Y; Miyazaki J; Hoffman RM In Vivo; 2022; 36(6):2598-2603. PubMed ID: 36309364 [TBL] [Abstract][Full Text] [Related]
17. Metabolic targeting with recombinant methioninase combined with palbociclib regresses a doxorubicin-resistant dedifferentiated liposarcoma. Igarashi K; Kawaguchi K; Kiyuna T; Miyake K; Miyaki M; Yamamoto N; Hayashi K; Kimura H; Miwa S; Higuchi T; Singh AS; Chmielowski B; Nelson SD; Russell TA; Eckardt MA; Dry SM; Li Y; Singh SR; Chawla SP; Eilber FC; Tsuchiya H; Hoffman RM Biochem Biophys Res Commun; 2018 Dec; 506(4):912-917. PubMed ID: 30392912 [TBL] [Abstract][Full Text] [Related]
18. Oral-recombinant Methioninase Converts an Osteosarcoma from Methotrexate-resistant to -sensitive in a Patient-derived Orthotopic-xenograft (PDOX) Mouse Model. Aoki Y; Tome Y; Han Q; Yamamoto J; Hamada K; Masaki N; Kubota Y; Bouvet M; Nishida K; Hoffman RM Anticancer Res; 2022 Feb; 42(2):731-737. PubMed ID: 35093871 [TBL] [Abstract][Full Text] [Related]