BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 33122192)

  • 1. A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms.
    Stefano JE; Lord DM; Zhou Y; Jaworski J; Hopke J; Travaline T; Zhang N; Wong K; Lennon A; He T; Bric-Furlong E; Cherrie C; Magnay T; Remy E; Brondyk W; Qiu H; Radošević K
    J Biol Chem; 2020 Dec; 295(52):18379-18389. PubMed ID: 33122192
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of CD73 AMP hydrolysis by a therapeutic antibody with a dual, non-competitive mechanism of action.
    Geoghegan JC; Diedrich G; Lu X; Rosenthal K; Sachsenmeier KF; Wu H; Dall'Acqua WF; Damschroder MM
    MAbs; 2016; 8(3):454-67. PubMed ID: 26854859
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Small-molecule CD73 inhibitors for the immunotherapy of cancer: a patent and literature review (2017-present).
    Nocentini A; Capasso C; Supuran CT
    Expert Opin Ther Pat; 2021 Oct; 31(10):867-876. PubMed ID: 33909515
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structure of a soluble form of human CD73 with ecto-5'-nucleotidase activity.
    Heuts DP; Weissenborn MJ; Olkhov RV; Shaw AM; Gummadova J; Levy C; Scrutton NS
    Chembiochem; 2012 Nov; 13(16):2384-91. PubMed ID: 22997138
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Anti-human CD73 monoclonal antibody inhibits metastasis formation in human breast cancer by inducing clustering and internalization of CD73 expressed on the surface of cancer cells.
    Terp MG; Olesen KA; Arnspang EC; Lund RR; Lagerholm BC; Ditzel HJ; Leth-Larsen R
    J Immunol; 2013 Oct; 191(8):4165-73. PubMed ID: 24043904
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The first CD73-instructed supramolecular hydrogel.
    Wu D; Du X; Shi J; Zhou J; Zhou N; Xu B
    J Colloid Interface Sci; 2015 Jun; 447():269-72. PubMed ID: 25524006
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes.
    Bhattarai S; Pippel J; Scaletti E; Idris R; Freundlieb M; Rolshoven G; Renn C; Lee SY; Abdelrahman A; Zimmermann H; El-Tayeb A; Müller CE; Sträter N
    J Med Chem; 2020 Mar; 63(6):2941-2957. PubMed ID: 32045236
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural and functional characterization of engineered bifunctional fusion proteins of CD39 and CD73 ectonucleotidases.
    Zhong EH; Ledderose C; De Andrade Mello P; Enjyoji K; Lunderberg JM; Junger W; Robson SC
    Am J Physiol Cell Physiol; 2021 Jan; 320(1):C15-C29. PubMed ID: 33052071
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The SH-3 and SH-4 antibodies recognize distinct epitopes on CD73 from human mesenchymal stem cells.
    Barry F; Boynton R; Murphy M; Haynesworth S; Zaia J
    Biochem Biophys Res Commun; 2001 Nov; 289(2):519-24. PubMed ID: 11716504
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting Metabolism of Extracellular Nucleotides via Inhibition of Ectonucleotidases CD73 and CD39.
    Jeffrey JL; Lawson KV; Powers JP
    J Med Chem; 2020 Nov; 63(22):13444-13465. PubMed ID: 32786396
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting two distinct epitopes on human CD73 with a bispecific antibody improves anticancer activity.
    Gammelgaard OL; Terp MG; Renn C; Labrijn AF; Hamaker O; Nielsen AY; Vever H; Hansen SW; Gjerstorff MF; Müller CE; Parren PW; Ditzel HJ
    J Immunother Cancer; 2022 Sep; 10(9):. PubMed ID: 36096528
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CD73 Promotes Resistance to HER2/ErbB2 Antibody Therapy.
    Turcotte M; Allard D; Mittal D; Bareche Y; Buisseret L; José V; Pommey S; Delisle V; Loi S; Joensuu H; Kellokumpu-Lehtinen PL; Sotiriou C; Smyth MJ; Stagg J
    Cancer Res; 2017 Oct; 77(20):5652-5663. PubMed ID: 28855210
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CD73 as a potential opportunity for cancer immunotherapy.
    Ghalamfarsa G; Kazemi MH; Raoofi Mohseni S; Masjedi A; Hojjat-Farsangi M; Azizi G; Yousefi M; Jadidi-Niaragh F
    Expert Opin Ther Targets; 2019 Feb; 23(2):127-142. PubMed ID: 30556751
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of Potent and Selective Methylenephosphonic Acid CD73 Inhibitors.
    Sharif EU; Kalisiak J; Lawson KV; Miles DH; Newcomb E; Lindsey EA; Rosen BR; Debien LPP; Chen A; Zhao X; Young SW; Walker NP; Sträter N; Scaletti ER; Jin L; Xu G; Leleti MR; Powers JP
    J Med Chem; 2021 Jan; 64(1):845-860. PubMed ID: 33399453
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody-Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function.
    Jin R; Liu L; Xing Y; Meng T; Ma L; Pei J; Cong Y; Zhang X; Ren Z; Wang X; Shen J; Yu K
    Mol Cancer Ther; 2020 Nov; 19(11):2340-2352. PubMed ID: 32943546
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis.
    Stagg J; Divisekera U; McLaughlin N; Sharkey J; Pommey S; Denoyer D; Dwyer KM; Smyth MJ
    Proc Natl Acad Sci U S A; 2010 Jan; 107(4):1547-52. PubMed ID: 20080644
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ectonucleotidases CD39 and CD73 on OvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity.
    Häusler SF; Montalbán del Barrio I; Strohschein J; Chandran PA; Engel JB; Hönig A; Ossadnik M; Horn E; Fischer B; Krockenberger M; Heuer S; Seida AA; Junker M; Kneitz H; Kloor D; Klotz KN; Dietl J; Wischhusen J
    Cancer Immunol Immunother; 2011 Oct; 60(10):1405-18. PubMed ID: 21638125
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ecto-enzyme and signaling functions of lymphocyte CD73.
    Resta R; Yamashita Y; Thompson LF
    Immunol Rev; 1998 Feb; 161():95-109. PubMed ID: 9553767
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Enhancement of colorectal tumor targeting using a novel biparatopic monoclonal antibody against carcinoembryonic antigen in experimental radioimmunoguided surgery.
    Kim JC; Roh SA; Koo KH; Ryu JH; Hong HK; Oh SJ; Ryu JS; Kim HJ; Bodmer WF
    Int J Cancer; 2002 Feb; 97(4):542-7. PubMed ID: 11802220
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The ectonucleotidases CD39 and CD73: Novel checkpoint inhibitor targets.
    Allard B; Longhi MS; Robson SC; Stagg J
    Immunol Rev; 2017 Mar; 276(1):121-144. PubMed ID: 28258700
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.