BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 33124982)

  • 1. A sulfur-aromatic gate latch is essential for opening of the Orai1 channel pore.
    Yeung PS; Ing CE; Yamashita M; Pomès R; Prakriya M
    Elife; 2020 Oct; 9():. PubMed ID: 33124982
    [TBL] [Abstract][Full Text] [Related]  

  • 2. STIM1 activates CRAC channels through rotation of the pore helix to open a hydrophobic gate.
    Yamashita M; Yeung PS; Ing CE; McNally BA; Pomès R; Prakriya M
    Nat Commun; 2017 Feb; 8():14512. PubMed ID: 28220789
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CRAC channel opening is determined by a series of Orai1 gating checkpoints in the transmembrane and cytosolic regions.
    Tiffner A; Schober R; Höglinger C; Bonhenry D; Pandey S; Lunz V; Sallinger M; Frischauf I; Fahrner M; Lindinger S; Maltan L; Berlansky S; Stadlbauer M; Schindl R; Ettrich R; Romanin C; Derler I
    J Biol Chem; 2021; 296():100224. PubMed ID: 33361160
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pore properties of Orai1 calcium channel dimers and their activation by the STIM1 ER calcium sensor.
    Cai X; Nwokonko RM; Loktionova NA; Abdulqadir R; Baraniak JH; Wang Y; Trebak M; Zhou Y; Gill DL
    J Biol Chem; 2018 Aug; 293(33):12962-12974. PubMed ID: 29954946
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The basic residues in the Orai1 channel inner pore promote opening of the outer hydrophobic gate.
    Yamashita M; Ing CE; Yeung PS; Maneshi MM; Pomès R; Prakriya M
    J Gen Physiol; 2020 Jan; 152(1):. PubMed ID: 31816637
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ca
    Bhardwaj R; Augustynek BS; Ercan-Herbst E; Kandasamy P; Seedorf M; Peinelt C; Hediger MA
    Cell Physiol Biochem; 2020 Mar; 54(2):252-270. PubMed ID: 32176842
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Twisting gating residues in the Orai pore.
    Bonhenry D; Schober R; Schindl R
    Cell Calcium; 2021 Jan; 93():102323. PubMed ID: 33316586
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The STIM1-binding site nexus remotely controls Orai1 channel gating.
    Zhou Y; Cai X; Loktionova NA; Wang X; Nwokonko RM; Wang X; Wang Y; Rothberg BS; Trebak M; Gill DL
    Nat Commun; 2016 Dec; 7():13725. PubMed ID: 27929067
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 2-Aminoethoxydiphenyl Borate Potentiates CRAC Current by Directly Dilating the Pore of Open Orai1.
    Xu X; Ali S; Li Y; Yu H; Zhang M; Lu J; Xu T
    Sci Rep; 2016 Jul; 6():29304. PubMed ID: 27373367
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mapping the functional anatomy of Orai1 transmembrane domains for CRAC channel gating.
    Yeung PS; Yamashita M; Ing CE; Pomès R; Freymann DM; Prakriya M
    Proc Natl Acad Sci U S A; 2018 May; 115(22):E5193-E5202. PubMed ID: 29760086
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Conformational Changes in the Orai1 C-Terminus Evoked by STIM1 Binding.
    Tirado-Lee L; Yamashita M; Prakriya M
    PLoS One; 2015; 10(6):e0128622. PubMed ID: 26035642
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ORAI1 channel gating and selectivity is differentially altered by natural mutations in the first or third transmembrane domain.
    Bulla M; Gyimesi G; Kim JH; Bhardwaj R; Hediger MA; Frieden M; Demaurex N
    J Physiol; 2019 Jan; 597(2):561-582. PubMed ID: 30382595
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Functional Analysis of Orai1 Concatemers Supports a Hexameric Stoichiometry for the CRAC Channel.
    Yen M; Lokteva LA; Lewis RS
    Biophys J; 2016 Nov; 111(9):1897-1907. PubMed ID: 27806271
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular mechanisms of STIM/Orai communication.
    Derler I; Jardin I; Romanin C
    Am J Physiol Cell Physiol; 2016 Apr; 310(8):C643-62. PubMed ID: 26825122
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription.
    Frischauf I; Litviňuková M; Schober R; Zayats V; Svobodová B; Bonhenry D; Lunz V; Cappello S; Tociu L; Reha D; Stallinger A; Hochreiter A; Pammer T; Butorac C; Muik M; Groschner K; Bogeski I; Ettrich RH; Romanin C; Schindl R
    Sci Signal; 2017 Nov; 10(507):. PubMed ID: 29184031
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CRAC channels and disease - From human CRAC channelopathies and animal models to novel drugs.
    Feske S
    Cell Calcium; 2019 Jun; 80():112-116. PubMed ID: 31009822
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cooperative Binding of Stromal Interaction Molecule 1 (STIM1) to the N and C Termini of Calcium Release-activated Calcium Modulator 1 (Orai1).
    Palty R; Isacoff EY
    J Biol Chem; 2016 Jan; 291(1):334-41. PubMed ID: 26546674
    [TBL] [Abstract][Full Text] [Related]  

  • 18. STIM1-Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy.
    Navarro-Borelly L; Somasundaram A; Yamashita M; Ren D; Miller RJ; Prakriya M
    J Physiol; 2008 Nov; 586(22):5383-401. PubMed ID: 18832420
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural and Mechanistic Insights of CRAC Channel as a Drug Target in Autoimmune Disorder.
    Bhuvaneshwari S; Sankaranarayanan K
    Curr Drug Targets; 2020; 21(1):55-75. PubMed ID: 31556856
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ORAI1 Mutations with Distinct Channel Gating Defects in Tubular Aggregate Myopathy.
    Böhm J; Bulla M; Urquhart JE; Malfatti E; Williams SG; O'Sullivan J; Szlauer A; Koch C; Baranello G; Mora M; Ripolone M; Violano R; Moggio M; Kingston H; Dawson T; DeGoede CG; Nixon J; Boland A; Deleuze JF; Romero N; Newman WG; Demaurex N; Laporte J
    Hum Mutat; 2017 Apr; 38(4):426-438. PubMed ID: 28058752
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.