BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 33126762)

  • 1. Identification of Iminium Intermediates Generation in the Metabolism of Tepotinib Using LC-MS/MS: In Silico and Practical Approaches to Bioactivation Pathway Elucidation.
    Abdelhameed AS; Attwa MW; Kadi AA
    Molecules; 2020 Oct; 25(21):. PubMed ID: 33126762
    [TBL] [Abstract][Full Text] [Related]  

  • 2.
    Alsubi TA; Attwa MW; Bakheit AH; Darwish HW; Abuelizz HA; Kadi AA
    RSC Adv; 2020 Jun; 10(38):22668-22683. PubMed ID: 35514564
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Investigation of Fenebrutinib Metabolism and Bioactivation Using MS
    Alsibaee AM; Aljohar HI; Attwa MW; Abdelhameed AS; Kadi AA
    Molecules; 2023 May; 28(10):. PubMed ID: 37241965
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reactive intermediates formation and bioactivation pathways of spebrutinib revealed by LC-MS/MS:
    Alsibaee AM; Aljohar HI; Attwa MW; Abdelhameed AS; Kadi AA
    Heliyon; 2023 Jun; 9(6):e17058. PubMed ID: 37484253
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phase I metabolic profiling and unexpected reactive metabolites in human liver microsome incubations of X-376 using LC-MS/MS: bioactivation pathway elucidation and
    Attwa MW; Kadi AA; Abdelhameed AS
    RSC Adv; 2020 Jan; 10(9):5412-5427. PubMed ID: 35498318
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Piperazine ring toxicity in three novel anti-breast cancer drugs: an in silico and in vitro metabolic bioactivation approach using olaparib as a case study.
    Alsubi TA; Attwa MW; Darwish HW; Abuelizz HA; Kadi AA
    Naunyn Schmiedebergs Arch Pharmacol; 2023 Jul; 396(7):1435-1450. PubMed ID: 36738368
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of Stable and Reactive Metabolites of the Anticancer Drug, Ensartinib, in Human Liver Microsomes Using LC-MS/MS: An in silico and Practical Bioactivation Approach.
    Abdelhameed AS; Attwa MW; Kadi AA
    Drug Des Devel Ther; 2020; 14():5259-5273. PubMed ID: 33299299
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification and characterization of
    Al-Shakliah NS; Attwa MW; AlRabiah H; Kadi AA
    Anal Methods; 2021 Jan; 13(3):399-410. PubMed ID: 33410830
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of reactive intermediate formation and bioactivation pathways in Abemaciclib metabolism by LC-MS/MS:
    Kadi AA; Darwish HW; Abuelizz HA; Alsubi TA; Attwa MW
    R Soc Open Sci; 2019 Jan; 6(1):181714. PubMed ID: 30800400
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification and characterization of
    Al-Shakliah NS; Attwa MW; Kadi AA; AlRabiah H
    RSC Adv; 2020 Apr; 10(28):16231-16244. PubMed ID: 35498820
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Detection and characterization of olmutinib reactive metabolites by LC-MS/MS: Elucidation of bioactivation pathways.
    Attwa MW; Kadi AA; Abdelhameed AS
    J Sep Sci; 2020 Feb; 43(4):708-718. PubMed ID: 31788977
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Profiling of
    Al-Shakliah NS; Kadi AA; Aljohar HI; AlRabiah H; Attwa MW
    RSC Adv; 2022 Jul; 12(32):20991-21003. PubMed ID: 35919181
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ion Trap LC/MS reveals the generation of reactive intermediates in acalabrutinib metabolism: phase I metabolic profiling and bioactivation pathways elucidation.
    Alsibaee AM; Aljohar HI; Attwa MW; Abdelhameed AS; Kadi AA
    RSC Adv; 2024 May; 14(23):16170-16193. PubMed ID: 38769961
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sapitinib: reactive intermediates and bioactivation pathways characterized by LC-MS/MS.
    Attwa MW; Kadi AA
    RSC Adv; 2019 Oct; 9(57):32995-33006. PubMed ID: 35529145
    [TBL] [Abstract][Full Text] [Related]  

  • 15. LC-ESI-MS/MS reveals the formation of reactive intermediates in brigatinib metabolism: elucidation of bioactivation pathways.
    Kadi AA; Attwa MW; Darwish HW
    RSC Adv; 2018 Jan; 8(3):1182-1190. PubMed ID: 35540908
    [TBL] [Abstract][Full Text] [Related]  

  • 16. High resolution mass spectrometry-based methodologies for identification of Etravirine bioactivation to reactive metabolites: In vitro and in vivo approaches.
    Godinho ALA; Martins IL; Nunes J; Charneira C; Grilo J; Silva DM; Pereira SA; Soto K; Oliveira MC; Marques MM; Jacob CC; Antunes AMM
    Eur J Pharm Sci; 2018 Jul; 119():70-82. PubMed ID: 29592839
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reactive intermediates and bioactivation pathways characterization of avitinib by LC-MS/MS: In vitro metabolic investigation.
    Attwa MW; Kadi AA; Abdelhameed AS
    J Pharm Biomed Anal; 2019 Feb; 164():659-667. PubMed ID: 30472584
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolic Stability Assessment of New PARP Inhibitor Talazoparib Using Validated LC-MS/MS Methodology: In silico Metabolic Vulnerability and Toxicity Studies.
    Attwa MW; Kadi AA; Abdelhameed AS; Alhazmi HA
    Drug Des Devel Ther; 2020; 14():783-793. PubMed ID: 32158196
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of reactive intermediates formation in dacomitinib metabolism and bioactivation pathways elucidation by LC-MS/MS:
    Attwa MW; Kadi AA; Abdelhameed AS
    RSC Adv; 2018 Nov; 8(68):38733-38744. PubMed ID: 35558335
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reactive intermediates in naquotinib metabolism identified by liquid chromatography-tandem mass spectrometry: phase I metabolic profiling.
    Attwa MW; Kadi AA; AlRabiah H; Darwish HW
    RSC Adv; 2019 Mar; 9(18):10211-10225. PubMed ID: 35520926
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.